JORGE ELIAS KALIL FILHO

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Departamento de Clínica Médica, Faculdade de Medicina - Docente
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/19 - Laboratório de Histocompatibilidade e Imunidade Celular, Hospital das Clínicas, Faculdade de Medicina - Líder

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Autor: GIAVINA-BIANCHI, Pedro ×

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Agora exibindo 1 - 10 de 79
  • bookPart
    Imunobiológicos
    (2022) AGONDI, Rosana Câmara; GIAVINA-BIANCHI, Pedro; KALIL, Jorge
  • article 20 Citação(ões) na Scopus
    Drug-induced anaphylaxis: is it an epidemic?
    (2018) GIAVINA-BIANCHI, Pedro; AUN, Marcelo V.; KALIL, Jorge
    Purpose of reviewThe present review addresses the epidemiology, analyzes the current data and promotes global awareness of drug-induced anaphylaxis.Recent findingsAnaphylaxis is a medical emergency that may cause death! In the last decade, studies have shown an increasing incidence and prevalence of anaphylaxis.SummaryDrug-induced anaphylaxis fatalities have increased, and this syndrome remains underdiagnosed and undertreated.
  • conferenceObject
    Inhaled corticoids in asthmatic patients: effect on body mass index and spirometry
    (2018) PACHECO, Rosilane dos Reis; ANDRADE, Mayra Coutinho; PEDROSO, Natalia Falci; TAKEJIMA, Priscila; AUN, Marcelo V.; KALIL FILHO, Jorge Elias; GIAVINA-BIANCHI, Pedro; AGONDI, Rosana C.
  • article 3 Citação(ões) na Scopus
    Inter- and intra-patient heterogeneity of PD-L1 expression in metastatic melanomas: A retrospective study
    (2021) GIAVINA-BIANCHI, Mara; SOTTO, Mirian Nacagamo; GIAVINA-BIANCHI, Pedro; MUNHOZ, Rodrigo; NETO, Cyro Festa; KALIL, Jorge
  • conferenceObject
    Frequency Of Anti-inflammatory Related Cutaneous Manifestation In Patients With Aspirin-exacerbated Respiratory Disease (AERD)
    (2018) ANDRADE, Mayra Coutinho; PACHECO, Rosilane dos Reis; ALMEIDA, Mila; TAKEJIMA, Priscila; KALIL FILHO, Jorge Elias; GIAVINA-BIANCHI, Pedro; AGONDI, Rosana C.
  • conferenceObject
    Esophagogastroduodenal Mucosal Behavior after Bronchial Challenge with House Dust Mites in Allergic Asthmatic Patients
    (2015) AGONDI, Rosana C.; NAVARRO-RODRIGUEZ, Tomas; BARBUTI, Ricardo; BISACCIONI, Carla; AUN, Marcelo Vivolo; KALIL, Jorge; GIAVINA-BIANCHI, Pedro
  • conferenceObject
    AERD: PERSPECTIVE OF THE USE OF LICENSED MONOCLONALS FOR TREATMENT BASED ON THEIR PHENOTYPES
    (2019) DIAS, Gabriella M. F. S.; ASSIS, Joao Paulo de; CASTRO, Raisa Borges; KALIL, Jorge; GIAVINA-BIANCHI, Pedro; AGONDI, Rosana C.
  • article 25 Citação(ões) na Scopus
    Anaphylaxis to quinolones in mastocytosis: Hypothesis on the mechanism
    (2019) GIAVINA-BIANCHI, Pedro; GONCALVES, Danilo Gois; ZANANDREA, Andressa; CASTRO, Raisa Borges de; GARRO, Laila Sabino; KALIL, Jorge; CASTELLS, Mariana
  • article 0 Citação(ões) na Scopus
    Hypersensitivity to dipyrone in aspirin-exacerbated respiratory disease patients is associated with urticaria
    (2020) AGONDI, Rosana Camara; DIAS, Gabriella Melo Fontes Silva; ASSIS, Joao Paulo de; PACHECO, Rosilane; KALIL, Jorge; GIAVINA-BIANCHI, Pedro
    Objective: To phenotype patients with aspirin-exacerbated respiratory disease (AERD) according to the presence of atopy, urticaria and level of peripheral eosinophils. Methods: This study included adult asthmatic patients with AERD followed up at a tertiary hospital. They were classified according to atopy and/or urticaria, assessing clinical and laboratorial differences among the groups in order to identify possible aggravating factors of the disease. Results: We included 73 patients, 78.1% being female with a mean age of 54.0 years. Severe asthma was observed in 68.5% and respiratory exacerbation with dipyrone in 67.1% of these patients. They had median total serum IgE of 191.6 IU/mL, mean peripheral eosinophils of 718.5 cells/mm(3), and 50.7% were atopic. Urticaria was observed in 32.9% of them, and exacerbations were more often triggered by dipyrone (p = .016). Atopic patients were younger than nonatopic patients (p = .023), and had, on average, higher total serum IgE levels (p = .022). We observed a good correlation between asthma severity and peripheral eosinophils count (r(2) = 026; p = .021). Conclusions: In this study, severe asthma was highly prevalent in AERD patients. Likewise, urticaria was quite prevalent and its presence was associated with dipyrone induced hypersensitivity reaction. Atopy was found in half of the patients, with no association with asthma severity. Patients with higher levels of peripheral eosinophils had more severe asthma. Dypirone hypersensitivity may be a marker for concomitant respiratory and cutaneous hypersensitivity reactions.
  • bookPart
    Terapia monoclonal nas doenças alérgicas
    (2021) AGONDI, Rosana Câmara; GIAVINA-BIANCHI, Pedro; KALIL FILHO, Jorge Elias