LETICIA BARBOSA KAWANO DOURADO
Projetos de Pesquisa
Unidades Organizacionais
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
conferenceObject High Resolution Computer Tomography Analysis Of A Cohort Of Mixed Connective Tissue Disease (mctd) Patients: 10 Years Of Follow-Up(2013) KAWANO-DOURADO, L.; DIAS, O. M.; KAY, F.; GRIPP, T.; GOMES, P.; CALEIRO, M.; KAIRALLA, R.; CARVALHO, C. R. R.conferenceObject Evaluation and correlations of the extension of pulmonary cysts in lymphangioleiomyomatosis(2013) ARAUJO, Mariana Sponholz; FREITAS, Carolina Salim Goncalves; BALDI, Bruno Guedes; TELES, Gustavo Borges da Silva; PIMENTA, Suzana Pinheiro; PEREIRA, Daniel Antunes Silva; DIAS, Olivia Meira; COSTA, Andre Nathan; KAWANO-DOURADO, Leticia; KAWASSAKI, Alexandre; KAIRALLA, Ronaldo Adib; CARVALHO, Carlos Roberto RibeiroconferenceObject 10-Year Follow-Up Of Pulmonary Function In Mixed Connective Tissue Disease(2013) KAWANO-DOURADO, L.; DIAS, O. M.; KAY, F. U.; GRIPP, T. E. H.; GOMES, P. S.; CALEIRO, M. C.; FULLER, R.; KAIRALLA, R. A.; CARVALHO, C. R. R.article 9 Citação(ões) na Scopus Environmental triggers of autoimmunity in anti-synthetase syndrome: the lungs under the spot light(2013) KAWANO-DOURADO, L.; COSTA, A. N.; CARVALHO, C. R. R.; KAIRALLA, R. A.The prevalence of interstitial lung involvement in anti-synthetase syndrome (anti-SS) may be as high as 70% and is a major contributor to morbidity and mortality. Histidyl-tRNA synthetase (Jo-1) is the most common autoantigenic target among the aminoacyl-tRNA A synthetases. We report two well documented anti-SS cases where it was observed significant exposure to a known inhaled offending antigen, development of a lymphocytic interstitial lung disease (ILD) and negative auto-antibodies, interpreted at first as hypersensitivity pneumonitis. Only after 14 and 30 months, respectively, the development of systemic symptoms compatible with anti-SS and anti-Jo-1 was observed. A growing body of evidence suggests that the lungs are the environment in which Jo-1 autoimmunity may be initiated and propagated. The description of the clinical and laboratorial evolution of these patients together with accumulated evidence of biological plausibility support the hypothesis that anti-SS can follow an episode of lung inflammation secondary to inhaled antigen exposure.conferenceObject Features Of A Brazilian Cohort Of Patients With Lung-Dominant Connective Tissue Disease (ld-CTd)(2013) PEREIRA, D. A. S.; DIAS, O. M.; ALMEIDA, G. E.; ARAUJO, M. S.; KAWANO-DOURADO, L.; KAIRALLA, R. A.; CARVALHO, C. R. R.; BALDI, B. G.- Usual interstitial pneumonia: a pattern or a disease? A reflection upon the topic(2013) KAWANO-DOURADO, Leticia; KAIRALLA, Ronaldo Adib
conferenceObject Pulmonary Involvement In Mixed Connective Tissue Disease: Slow Progression After 10 Years Of Follow-Up(2013) KAWANO-DOURADO, Leticia; DIAS, Olivia M.; KAY, Fernando U.; GRIPP, Thais E. H.; GOMES, Paula S.; FULLER, Ricardo; BALDI, Bruno G.; KAIRALLA, Ronaldo A.; CARVALHO, Carlos R. R.; CALEIRO, M. Teresa C.