ROSANA CAMARA AGONDI
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/60 - Laboratório de Imunologia Clínica e Alergia, Hospital das Clínicas, Faculdade de Medicina
LIM/19 - Laboratório de Histocompatibilidade e Imunidade Celular, Hospital das Clínicas, Faculdade de Medicina
LIM/60 - Laboratório de Imunologia Clínica e Alergia, Hospital das Clínicas, Faculdade de Medicina
LIM/19 - Laboratório de Histocompatibilidade e Imunidade Celular, Hospital das Clínicas, Faculdade de Medicina
17 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 17
- Hypersensitivity to dipyrone in aspirin-exacerbated respiratory disease patients is associated with urticaria(2020) AGONDI, Rosana Camara; DIAS, Gabriella Melo Fontes Silva; ASSIS, Joao Paulo de; PACHECO, Rosilane; KALIL, Jorge; GIAVINA-BIANCHI, PedroObjective: To phenotype patients with aspirin-exacerbated respiratory disease (AERD) according to the presence of atopy, urticaria and level of peripheral eosinophils. Methods: This study included adult asthmatic patients with AERD followed up at a tertiary hospital. They were classified according to atopy and/or urticaria, assessing clinical and laboratorial differences among the groups in order to identify possible aggravating factors of the disease. Results: We included 73 patients, 78.1% being female with a mean age of 54.0 years. Severe asthma was observed in 68.5% and respiratory exacerbation with dipyrone in 67.1% of these patients. They had median total serum IgE of 191.6 IU/mL, mean peripheral eosinophils of 718.5 cells/mm(3), and 50.7% were atopic. Urticaria was observed in 32.9% of them, and exacerbations were more often triggered by dipyrone (p = .016). Atopic patients were younger than nonatopic patients (p = .023), and had, on average, higher total serum IgE levels (p = .022). We observed a good correlation between asthma severity and peripheral eosinophils count (r(2) = 026; p = .021). Conclusions: In this study, severe asthma was highly prevalent in AERD patients. Likewise, urticaria was quite prevalent and its presence was associated with dipyrone induced hypersensitivity reaction. Atopy was found in half of the patients, with no association with asthma severity. Patients with higher levels of peripheral eosinophils had more severe asthma. Dypirone hypersensitivity may be a marker for concomitant respiratory and cutaneous hypersensitivity reactions.
conferenceObject Biomarkers in patients with refractory chronic spontaneous urticaria(2020) PEREZ, I. L.; GOMES, L. S.; PEREIRA, G. F.; ARAUJO, A. M.; MAMEDE, L. Q.; SOUZA, A. B.; MOTTA, A. A.; KALIL, J.; AGONDI, R. C.conferenceObject Correlation between total serum IgE levels and sensibilization to aeroallergens(2020) BIALOWAS, D.; PACHANI, M. A. D. S.; ZANETTI, F. A.; GIAVINA-BIANCHI JUNIOR, P. F.; KALIL, J.; AGONDI, R. C.conferenceObject Vasculitis in patients with chronic urticaria or autoimmune diseases(2020) FRANCO, G. R.; PRADO, A. I. F.; MAMEDE, L. Q.; GIAVINA-BIANCHI, M.; KALIL, J.; MOTTA, A. A.; BARROS, M. T.; AGONDI, R. C.conferenceObject Influence of emotional stress on clinical presentation of chronic urticaria patient(2020) ARAUJO, A. M. F. E. Sousa; COSENTINO, J. B. M.; PEREZ, I. L.; GOMES, L. S.; MAMEDE, L. D. Q.; PEREIRA, G. D. F.; SOUSA, A. B. D.; MOTTA, A. A.; KALIL, J.; AGONDI, R. C.conferenceObject Are N-ERD really a non atopic disease? Comparative between the phenotype allergic and nonallergic in N-ERD in a Brazilian cohort(2020) DIAS, G. M. F. S.; KALIL, J.; GIAVINA-BIANCHI, P.; AGONDI, R. C.conferenceObject Inhaled corticosteroid use and its implication in peripheral eosinophil level(2020) PEREIRA, G. D. F.; FRANCO, P. D. A.; GOMES, L. S.; MAMEDE, L. D. Q.; PEREZ, I. L.; ARAUJO, A. M. F. E. S.; BIANCHI, P. G.; AGONDI, R. C.- Debate on drugs that may aggravate COVID-19(2020) GIAVINA-BIANCHI, Pedro; AUN, Marcelo Vivolo; AGONDI, Rosana C. Amara; KALIL, Jorge
conferenceObject Presence of angioedema in patients with chronic urticaria and montelukast response(2020) ARAUJO, A. M. F. E. S.; PEREZ, I. L.; GOMES, L. S.; MAMEDE, L. D. Q.; PEREIRA, G. D. F.; SOUZA, A. B. De; MOTTA, A. A.; KALIL, J.; AGONDI, R. C.conferenceObject Eosinophilia in asthmatic patients and its relationship with Aspirin-Exacerbated Respiratory Disease(2020) CUNHA, La Is; DIAS, Gabriella; GIAVINA-BIANCHI, Pedro; KALIL, Jorge; AGONDI, Rosana