THIAGO MACHADO NOGUEIRA
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/30 - Laboratório de Investigação em Cirurgia Pediát, Hospital das Clínicas, Faculdade de Medicina
LIM/30 - Laboratório de Investigação em Cirurgia Pediát, Hospital das Clínicas, Faculdade de Medicina
3 resultados
Resultados de Busca
Agora exibindo 1 - 3 de 3
- Radiographic Characteristics of Adrenal Masses Preceding the Diagnosis of Adrenocortical Cancer(2015) NOGUEIRA, T. M.; LIROV, R.; CAOILI, E. M.; LERARIO, A. M.; MILLER, B. S.; FRAGOSO, M. C. B. V.; DUNNICK, N. R.; HAMMER, G. D.; ELSE, T.Incidentally discovered adrenal masses are common and the clinical evaluation and surveillance aims to diagnose hormone excess and malignancy. Adrenocortical cancer (ACC) is a very rare malignancy. This study aims to define the imaging characteristics of adrenal tumors preceding the diagnosis of ACC. Patients with prior (> 5 months) adrenal tumors (< 6 cm) subsequently diagnosed with ACC were identified in a large registry at a tertiary referral center. Retrospective chart and image review for patient characteristics and initial, interval, and diagnostic imaging characteristics (size, homogeneity, borders, density, growth rate, etc.) was conducted. Twenty patients with a diagnosis of ACC and a prior adrenal tumor were identified among 422 patients with ACC. Of these, 17 patients were initially imaged with CT and 3 with MR. Only 2 of the 20 patients had initial imaging characteristics suggestive of a benign lesion. Of initial tumors, 25 % were < 2 cm in size. Surveillance led to the diagnosis of ACC within 24 months in 50 % of patients. The growth pattern was variable with some lesions showing long-term stability (up to 8 years) in size. In conclusion, antecedent lesions in patients with a diagnosis of ACC are often indeterminate by imaging criteria and can be small. Surveillance over 2 years detected only 50 % of ACCs. Current practice and guidelines are insufficient in diagnosing ACCs. Given the rarity of ACC, the increased risk and health care costs of additional evaluation may not be warranted.
conferenceObject A Comparative Study of Pre- and Postoperative Quantification of Upper Eyelid Retraction in Graves Orbitopathy Using Margin Reflex Distance and Digital Eyelid Image Processing Methods(2014) NOGUEIRA, Thiago Machado; GONCALVES, Allan Pieroni; GONCALVES, Ana Carolina Arato; SILVA, Luzia Diegues; MONTEIRO, Mario Luiz RibeiroconferenceObject Radiographic Characteristics of Incidentalomas in Patients Later Diagnosed with Adrenocortical Cancer(2014) NOGUEIRA, Thiago Machado; LIROV, Roy; LERARIO, Antonio M.; HAMMER, Gary D.; FRAGOSO, Maria Candida B. V.; CAOILI, Elaine M.; ELSE, Tobias