SERGIO CARLOS NAHAS

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Lattes
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Departamento de Gastroenterologia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico

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  • article 57 Citação(ões) na Scopus
    Transient Ischemic Rectitis as a Potential Complication after Prostatic Artery Embolization: Case Report and Review of the Literature
    (2013) MOREIRA, Airton Mota; MARQUES, Carlos Frederico Sparapan; ANTUNES, Alberto Azoubel; NAHAS, Caio Sergio Rizkallah; NAHAS, Sergio Carlos; ARIZA, Miguel Angel de Gregorio; CARNEVALE, Francisco Cesar
    Prostatic artery embolization (PAE) is an alternative treatment for benign prostatic hyperplasia. Complications are primarily related to non-target embolization. We report a case of ischemic rectitis in a 76-year-old man with significant lower urinary tract symptoms due to benign prostatic hyperplasia, probably related to nontarget embolization. Magnetic resonance imaging revealed an 85.5-g prostate and urodynamic studies confirmed Inferior vesical obstruction. PAE was performed bilaterally. During the first 3 days of follow-up, a small amount of blood mixed in the stool was observed. Colonoscopy identified rectal ulcers at day 4, which had then disappeared by day 16 post PAE without treatment. PAE is a safe, effective procedure with a low complication rate, but interventionalists should be aware of the risk of rectal nontarget embolization.
  • article 108 Citação(ões) na Scopus
    Characteristics of Early-Onset vs Late-Onset Colorectal Cancer A Review
    (2021) ZABOROWSKI, Alexandra M.; ABDILE, Ahmed; ADAMINA, Michel; AIGNER, Felix; D'ALLENS, Laura; ALLMER, Caterina; ALVAREZ, Andrea; ANULA, Rocio; ANDRIC, Mihailo; ATALLAH, Sam; BACH, Simon; FAES, Seraina; FAIZ, Omar; FLEMING, Fergal; FOPPA, Caterina; FOWLER, George; FRASSON, Matteo; FIGUEIREDO, Nuno; FORGAN, Tim; FRIZELLE, Frank; KRONBERGER, Irmgard; SCHNEIDER, Martin; GADAEV, Shamil; GELLONA, Jose; GLYN, Tamara; GONG, Jianping; GORAN, Barisic; GREENWOOD, Emma; GUREN, Marianne G.; GUILLON, Stephanie; GUTLIC, Ida; HAHNLOSER, Dieter; SEISHIMA, Ryo; KROON, Hidde Maarten; HAMPEL, Heather; HANLY, Ann; HASEGAWA, Hirotoshi; IVERSEN, Lene Hjerrild; HILL, Andrew; HILL, James; HOCH, Jiri; HOFFMEISTER, Michael; HOMPES, Roel; SEKULIC, Aleksandar; HURTADO, Luis; BALA, Miklosh; IAQUINANDI, Fabiano; IMBRASAITE, Ugne; ISLAM, Rumana; JAFARI, Mehrenah Dorna; KANEMITSU, Yukihide; KARACHUN, Aleksei; KARIMUDDIN, Ahmer A.; KELLER, Deborah S.; SEPPALA, Toni; KELLY, Justin; KENNELLY, Rory; KRYZAUSKAS, Marius; KHRYKOV, Gleb; KURAL, Said; KUSTERS, Miranda; LAKKIS, Zaher; LANKOV, Timur; LARSON, Dave; LAZAR, Gyorgy; SHEAHAN, Kieran; LEE, Kai-Yin; LEE, Suk Hwan; LEFEVRE, Jeremie H.; BARUSSAUD, Marie; LEPISTO, Anna; LIEU, Christopher; LOI, Lynette; LYNCH, Craig; MAILLOU-MARTINAUD, Helene; MAROLI, Annalisa; SHINE, Rebecca; MARTIN, Sean; MARTLING, Anna; MATZEL, Klaus E.; MAYOL, Julio; BAUSYS, Augustinas; MCDERMOTT, Frank; MEURETTE, Guillaume; MILLAN, Monica; MITTEREGGER, Martin; MOISEENKO, Andrei; SHLOMINA, Alexandra; MONSON, John R. T.; MORARASU, Stefan; MORITANI, Konosuke; MOSLEIN, Gabriela; MUNINI, Martino; BEBINGTON, Brendan; NAHAS, Caio; NAHAS, Sergio; NEGOI, Ionut; NOVIKOVA, Anastasia; SICA, Guiseppe S.; OCARES, Misael; OKABAYASHI, Koji; OLKINA, Alexandra; ONATE-OCANA, Luis; OTERO, Jaime; OZEN, Cihan; BEGGS, Andrew; PACE, Ugo; JULIAO, Guilherme Pagin Sao; PANAIOTTI, Lidiia; SINGNOMKLAO, Tongplaew; PANIS, Yves; PAPAMICHAEL, Demetris; PARK, Jason; PATEL, Swati; URIBURU, Juan Carlos Patron; PERA, Miguel; PEREZ, Rodrigo O.; BELLOLIO, Felipe; PETROV, Alexei; PFEFFER, Frank; BEVAN, Vicki; PHANG, P. Terry; POSKUS, Tomas; PRINGLE, Heather; PROUD, David; RAGUZ, Ivana; RAMA, Nuno; RASHEED, Shahnawaz; RAVAL, Manoj J.; BENNETT, Melissa-Rose; REGA, Daniela; KOCIAN, Peter; REISSFELDER, Christoph; MENESES, Juan Carlos Reyes; RIS, Frederic; RISS, Stefan; RODRIGUEZ-ZENTNER, Homero; ROXBURGH, Campbell S.; SAKLANI, Avanish; SALIDO, Andrea Jimenez; SAMMOUR, Tarik; BERDINSKIKH, Anton; SIRAGUSA, Leandro; SARASTE, Deborah; SMART, Neil; SOLIS, Alejandro; SPINELLI, Antonino; STAIGER, Roxane D.; STAMOS, Michael J.; STEELE, Scott; SUNDERLAND, Michael; TAN, Ker-Kan; TANIS, Pieter J.; KOH, Cherry; BIONDO, Sebastiano; TEKKIS, Paris; TEKLAY, Biniam; TENGKU, Sabrina; JIMENEZ-TOSCANO, Marta; TSARKOV, Petr; TURINA, Matthias; ULRICH, Alexis; VAILATI, Bruna B.; HARTEN, Meike van; KOK, Neils; VERHOEF, Cornelis; BISLENGHI, Gabriele; WARRIER, Satish; WEXNER, Steve; WILT, Hans de; WEINBERG, Benjamin A.; WELLS, Cameron; WOLTHUIS, Albert; XYNOS, Evangelos; YOU, Nancy; KNIGHT, Katrina A.; ZAKHARENKO, Alexander; ZEBALLOS, Justino; BLUDAU, Marc; WINTER, Des C.; BOUTALL, Adam; BROUWER, Nelleke; BROWN, Carl; BRUNS, Christiane; BUCHANAN, Daniel D.; BUCHWALD, Pamela; KNOL, Joep; BURGER, Jacobus W. A.; BURLOV, Nikita; CAMPANELLI, Michela; CAPDEPONT, Maylis; CARVELLO, Michele; CHEW, Hwee-Hoon; CHRISTOFORIDIS, Dimitri; CLARK, David; CLIMENT, Marta; COLOGNE, Kyle G.; KONTOVOUNISIOS, Christos; CONTRERAS, Tomas; CRONER, Roland; DANIELS, Ian R.; DAPRI, Giovanni; DAVIES, Justin; DELRIO, Paolo; DENOST, Quentin; DEUTSCH, Michael; DIAS, Andre; D'HOORE, Andre; KORNER, Hartwig; DROZDOV, Evgeniy; DUEK, Daniel; DUNLOP, Malcolm; DZIKI, Adam; EDMUNDSON, Aleksandra; EFETOV, Sergey; EL-HUSSUNA, Alaa; ELLIOT, Brodie; EMILE, Sameh; ESPIN, Eloy; KRIVOKAPIC, Zoran; EVANS, Martyn
    IMPORTANCE The incidence of early-onset colorectal cancer (younger than 50 years) is rising globally, the reasons for which are unclear. It appears to represent a unique disease process with different clinical, pathological, and molecular characteristics compared with late-onset colorectal cancer. Data on oncological outcomes are limited, and sensitivity to conventional neoadjuvant and adjuvant therapy regimens appear to be unknown. The purpose of this review is to summarize the available literature on early-onset colorectal cancer. OBSERVATIONS Within the next decade, it is estimated that 1 in 10 colon cancers and 1 in 4 rectal cancers will be diagnosed in adults younger than 50 years. Potential risk factors include aWesternized diet, obesity, antibiotic usage, and alterations in the gut microbiome. Although genetic predisposition plays a role, most cases are sporadic. The full spectrum of germline and somatic sequence variations implicated remains unknown. Younger patients typically present with descending colonic or rectal cancer, advanced disease stage, and unfavorable histopathological features. Despite being more likely to receive neoadjuvant and adjuvant therapy, patients with early-onset disease demonstrate comparable oncological outcomes with their older counterparts. CONCLUSIONS AND RELEVANCE The clinicopathological features, underlying molecular profiles, and drivers of early-onset colorectal cancer differ from those of late-onset disease. Standardized, age-specific preventive, screening, diagnostic, and therapeutic strategies are required to optimize outcomes.