JOSE GALLUCCI NETO
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/27 - Laboratório de Neurociências, Hospital das Clínicas, Faculdade de Medicina
LIM/27 - Laboratório de Neurociências, Hospital das Clínicas, Faculdade de Medicina
4 resultados
Resultados de Busca
Agora exibindo 1 - 4 de 4
- Use of Magnetic Seizure Therapy for Treatment-Resistant Depression: A Case Series(2022) CRETAZ, Eric; BELLINI, Helena; GALLUCCI-NETO, Jose; CARNEIRO, Adriana Munhoz; SANTOS, Leonardo Afonso dos; MIRANDA, Cristiane Siqueira; BRUNONI, Andre Russowski
- Magnetic Waves vs. Electric Shocks: A Non-Inferiority Study of Magnetic Seizure Therapy and Electroconvulsive Therapy in Treatment-Resistant Depression(2023) BELLINI, Helena; CRETAZ, Eric; CARNEIRO, Adriana Munhoz; SILVA, Pedro Henrique Rodrigues da; SANTOS, Leonardo Afonso dos; GALLUCCI-NETO, Jose; BRUNONI, Andre RussowskyTreatment-resistant depression (TRD), characterized by the failure to achieve symptomatic remission despite multiple pharmacotherapeutic treatments, poses a significant challenge for clinicians. Electroconvulsive therapy (ECT) is an effective but limited option due to its cognitive side effects. In this context, magnetic seizure therapy (MST) has emerged as a promising alternative, offering comparable antidepressant efficacy with better cognitive outcomes. However, the clinical outcomes and cognitive effects of MST require further investigation. This double-blinded, randomized, non-inferiority study aims to compare the efficacy, tolerability, cognitive adverse effects, and neurophysiological biomarkers of MST with bilateral ECT (BT ECT) in patients with TRD. This study will employ multimodal nuclear magnetic resonance imaging (MRI) and serum neurotrophic markers to gain insight into the neurobiological basis of seizure therapy. Additionally, neurophysiological biomarkers will be evaluated as secondary outcomes to predict the antidepressant and cognitive effects of both techniques. The study design, recruitment methods, ethical considerations, eligibility criteria, interventions, and blinding procedures are described. The expected outcomes will advance the field by offering a potential alternative to ECT with improved cognitive outcomes and a better understanding of the underlying pathophysiology of depression and antidepressant therapies.
- Electroconvulsive therapy practice during the COVID-19 pandemic(2020) BELLINI, Helena; CRETAZ, Eric; RIGONATTI, Luiz Felipe; CONTO, Carla Dominique Rodrigues De; MELZER-RIBEIRO, Debora Luciana; BUSATTO-FILHO, Geraldo; BRUNONI, Andre Russowsky; GALLUCCI-NETO, Jose
- Images in Clinical Electroconvulsive Therapy Portable 1-Channel Electroencephalogram Device as Adjunctive Seizure Monitoring(2021) GALLUCCI-NETO, Jose; BELLINI, Helena; CRETAZ, Eric