ALBERTO AZOUBEL ANTUNES
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cirurgia, Faculdade de Medicina - Docente
LIM/55 - Laboratório de Urologia, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/55 - Laboratório de Urologia, Hospital das Clínicas, Faculdade de Medicina - Líder
19 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 19
conferenceObject LONG-TERM EVALUATION OF TRANSURETHRAL INCISION OF THE PROSTATE FOR TREATMENT OF BENIGN PROSTATE HYPERPLASIA: ANALYSIS OF 75 CASES WITH A MEAN 8-YEAR FOLLOW-UP PERIOD(2015) CORDEIRO, Paulo; BARONE, Hugo; YOSHINAGA, Eduardo Muracca; NAKANO, Elcio; NAHAS, William C.; SROUGI, Miguel; ANTUNES, Alberto A.- Interactions between Lower Urinary Tract Symptoms and Cardiovascular Risk Factors Determine Distinct Patterns of Erectile Dysfunction: A Latent Class Analysis(2013) BARBOSA, Joao A. B. A.; MURACCA, Eduardo; NAKANO, Elcio; ASSALIN, Adriana R.; CORDEIRO, Paulo; PARANHOS, Mario; CURY, Jose E.; SROUGI, Miguel; ANTUNES, Alberto A.Purpose: An epidemiological association between lower urinary tract symptoms and erectile dysfunction is well established. However, interactions among multiple risk factors and the role of each in pathological mechanisms are not fully elucidated Materials and Methods: We enrolled 898 men undergoing prostate cancer screening for evaluation with the International Prostate Symptom Score (I-PSS) and simplified International Index of Erectile Function-5 (IIEF-5) questionnaires. Age, race, hypertension, diabetes, dyslipidemia, metabolic syndrome, cardiovascular disease, serum hormones and anthropometric parameters were also evaluated. Risk factors for erectile dysfunction were identified by logistic regression. The 333 men with at least mild to moderate erectile dysfunction (IIEF 16 or less) were included in a latent class model to identify relationships across erectile dysfunction risk factors. Results: Age, hypertension, diabetes, lower urinary tract symptoms and cardiovascular event were independent predictors of erectile dysfunction (p < 0.05). We identified 3 latent classes of patients with erectile dysfunction (R-2 entropy = 0.82). Latent class 1 had younger men at low cardiovascular risk and a moderate/high prevalence of lower urinary tract symptoms. Latent class 2 had the oldest patients at moderate cardiovascular risk with an increased prevalence of lower urinary tract symptoms. Latent class 3 had men of intermediate age with the highest prevalence of cardiovascular risk factors and lower urinary tract symptoms. Erectile dysfunction severity and lower urinary tract symptoms increased from latent class 1 to 3. Conclusions: Risk factor interactions determined different severities of lower urinary tract symptoms and erectile dysfunction. The effect of lower urinary tract symptoms and cardiovascular risk outweighed that of age. While in the youngest patients lower urinary tract symptoms acted as a single risk factor for erectile dysfunction, the contribution of vascular disease resulted in significantly more severe dysfunction. Applying a risk factor interaction model to prospective trials could reveal distinct classes of drug responses and help define optimal treatment strategies for specific groups.
conferenceObject EXPRESSION PROFILE OF CD105 IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA (BPH): A NEW ANGIOGENIC MARKER(2013) BIOLO, Karlo; KIRIHARA, Ricardo; REIS, Sabrina T.; VIANA, Nayara I.; SAJOVIC, Paulo; ARAUJO, Luiz Henrique; LEITE, Katia R.; SROUGI, Miguel; ANTUNES, Alberto A.conferenceObject LOW-VOLUME PROSTATE IN BENIGN PROSTATIC HYPERPLASIA (BPH): A RISK FACTOR FOR SYMPTOMATIC BLADDER DIVERTICULA REQUIRING SURGICAL TREATMENT(2015) YOSHINAGA, Eduardo Muracca; NAKANO, Elcio; MARCHINI, Giovanni S.; OYAMA, Renato Hajime; CORDEIRO, Paulo; NAHAS, William C.; SROUGI, Miguel; ANTUNES, Alberto A.conferenceObject UNDER-EXPRESSION OF MICRORNA-155 MAY INHIBIT PROSTATE GROWTH THROUGH SMAD-2 PATHWAY IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA(2012) ANTUNES, Alberto A.; REIS, Sabrina; NAKANO, Elcio; BIOLO, Karlo; PARANHOS, Mario; CORDEIRO, Paulo; FREIRE, Geraldo Campos; LEITE, Katia; SROUGI, MiguelconferenceObject CAN WE PREDICT WHICH PATIENTS WILL PRESENT RESOLUTION OF DETRUSOROVERACTIVITY (DO) AFTER TRANSURETHRAL RESECTION OF THE PROSTATE (TURP)?(2015) ISCAIFE, Alexandre; REIS, Sabrina T.; ALBERTINI, Aline; NUNES, Marco A.; LUCON, Antonio M.; NAHAS, Willian C.; SROUGI, Miguel; ANTUNES, Alberto A.conferenceObject ROLE OF MICRORNAS IN REGULATING TISSUE INFLAMMATION IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA: PRELIMINARY RESULTS(2013) OLIVEIRA, Fabio; SAGAE, Vitor; REIS, Sabrina T.; VIANA, Nayara I.; LEITE, Katia R.; SROUGI, Miguel; ANTUNES, Alberto A.conferenceObject THE ROLE OF MICRORNA-126 AND SPRED1 IN BENIGN PROSTATIC HYPERPLASIA(2012) ANTUNES, Alberto A.; REIS, Sabrina; NAKANO, Elcio; BIOLO, Karlo; PARANHOS, Mario; CORDEIRO, Paulo; FREIRE, Geraldo Campos; LEITE, Katia; SROUGI, MiguelconferenceObject THE PAINFUL PELVIC SYMPTOMS IN AGING MEN. THE RESULTS OF POPULATION-BASED SAMPLE OF MEN(2016) NAKANO, Elcio; CONTI, Paulo Sajovic de; YOSHINAGA, Eduardo Muracca; NAHAS, William C.; SROUGI, Miguel; ANTUNES, AlbertoconferenceObject ROLE OF PHYSICAL ACTIVITY IN THE PREVENTION OF BPH THROUGH INHIBITION OF PROSTATIC IGF1/AKT PROLIFERATIVE AXIS: AN EXPERIMENTAL STUDY IN RATS.(2015) FONSECA, Fernando Froes; OLIVEIRA, Andre M.; REIS, Sabrina T.; LEITE, Katia R.; NAHAS, William C.; SROUGI, Miguel; ANTUNES, Alberto A.