CARLOS VICENTE SERRANO JUNIOR

(Fonte: Lattes)
Índice h a partir de 2011
15
Lattes
ORCID
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cardio-Pneumologia, Faculdade de Medicina - Docente
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina

Filtros

Limpar filtros

Configurações

search.filters.applied.f.dateIssued: 2021 ×

Resultados de Busca

Agora exibindo 1 - 8 de 8
  • bookPart
    Interconsulta em cardiologia
    (2021) JúNIOR, Renério Fráguas; SOUZA, Bruno Pinatti Ferreira; ANDREI, Anna Maria; ANDRADE, Milena Gross de; SERRANO JR., Carlos Vicente; WAJNGARTEN, Mauricio
  • conferenceObject
    Two-year Follow-up Of Patients With Chronic Ischemic Heart Disease In A Specialized Center In Brazil
    (2021) PINESI, Henrique Trombini; MOREIRA, Eduardo M.; BOLTA, Paula M.; MARTINS, Eduardo B.; PITTA, Fabio G.; REZENDE, Paulo C.; LIMA, Eduardo G.; HUEB, Whady; GARZILLO, Cibele L.; SERRANO, Carlos V.
  • article 0 Citação(ões) na Scopus
    Effect of diabetic kidney disease on therapeutic strategies for coronary artery disease: ten year follow-up
    (2021) BATISTA, Daniel Valente; HUEB, Whady; LIMA, Eduardo Gomes; REZENDE, Paulo Cury; GARZILLO, Cibele Larrosa; GARCIA, Rosa Maria Rahmi; LINHARES FILHO, Jaime Paula Pessoa; MARTINS, Eduardo Bello; SERRANO JUNIOR, Carlos Vicente; RAMIRES, Jose Antonio Franchini; KALIL FILHO, Roberto
    Background: The best treatment for coronary artery disease (CAD) in patients with type 2 diabetes (DM2) and chronic kidney disease is unknown. Methods: This retrospective study included MASS registry patients with DM2 and multivessel CAD, stratified by kidney function. Primary endpoint was combined of mortality, myocardial infarction, or additional revascularization. Results: Median follow-up was 9.5 years. Primary endpoint occurrences among strata 1 and 2 were 53.4% and 40.7%, respectively (P=.020). Mortality rates were 37.4% and 24.6% in strata 1 and 2, respectively (P<.001). We observed a lower rate of major adverse cardiovascular events (MACE) (P=.027 for stratum 1 and P<.001 for stratum 2) and additional revascularization (P=.001 for stratum 1 and P<.001 for stratum 2) for those in the surgical group. In a multivariate analysis, eGFR was an independent predictor of MACE (P=.034) and mortality (P=.020). Conclusions: Among subjects with DM2 and CAD the presence of lower eGFR rate was associated with higher rates of MACE and mortality, irrespective of treatment choice. CABG was associated with lower rates of MACE in both renal function strata. eGFR was an independent predictor of MACE and mortality in a 10-year follow-up.
  • conferenceObject
    The Inflammatory Response to Percutaneous Coronary Intervention is Related to Myocardial Injury in Patients with Chronic Ischemic Heart Disease
    (2021) FRISSO, Priscilla T.; MATTOS, Fernando R.; PINESI, Henrique Trombini; LEMOS, James A. De; PESARO, Antonio E.; RACHED, Fabiana H.; FRANKEN, Marcelo; CAIXETA, Adriano M.; LEMOS NETO, Pedro A.; CHAGAS, Antonio C.; SERRANO JR., Carlos V.
  • conferenceObject
    THE EVOLUTION OF RENAL FUNCTION IS NOT IMPACTED BY THE THERAPEUTIC MODALITY OF CORONARY ARTERY DISEASE IN DIABETIC PATIENTS. MASS REGISTRY 10-YEAR FOLLOW-UP
    (2021) BATISTA, Daniel Valente; LIMA, Eduardo; HUEB, Whady; LINHARES FILHO, Jaime; MARTINS, Eduardo; REZENDE, Paulo; RAMIRES, Jose; GARZILLO, Cibele; KALIL-FILHO, Roberto; SERRANO, Carlos
  • conferenceObject
    Diabetes and Chronic Kidney Disease: Prevalence, Associated Factors and Influence on Optimal Medical Therapy in Patients with Coronary Artery Disease
    (2021) MOREIRA, Eduardo M.; PINESI, Henrique Trombini; BOLTA, Paula; MARTINS, Eduardo; RACHED, Fabiana H.; PITTA, Fabio G.; FAVARATO, Desiderio; LIMA, Eduardo G.; GARZILLO, Cibele L.; SEGRE, Carlos A.; SERRANO, Carlos V.
  • article 4 Citação(ões) na Scopus
    Phospholipid transfer to high-density lipoprotein (HDL) upon triglyceride lipolysis is directly correlated with HDL-cholesterol levels and is not associated with cardiovascular risk
    (2021) MA, Feng; DARABI, Maryam; LHOMME, Marie; TUBEUF, Emilie; CANICIO, Aurelie; BRERAULT, Jean; MEDADJE, Narcisse; RACHED, Fabiana; LEBRETON, Sandrine; FRISDAL, Eric; BRITES, Fernando; SERRANO, Carlos; SANTOS, Raul; GAUTIER, Emmanuel; HUBY, Thierry; KHOURY, Petra El; CARRIE, Alain; ABIFADEL, Marianne; BRUCKERT, Eric; GUERIN, Maryse; COUVERT, Philippe; GIRAL, Philippe; LESNIK, Philippe; GOFF, Wilfried Le; GUILLAS, Isabelle; KONTUSH, Anatol
    Background and aims: While low concentrations of high-density lipoprotein-cholesterol (HDL-C) represent a wellestablished cardiovascular risk factor, extremely high HDL-C is paradoxically associated with elevated cardiovascular risk, resulting in the U-shape relationship with cardiovascular disease. Free cholesterol transfer to HDL upon lipolysis of triglyceride-rich lipoproteins (TGRL) was recently reported to underlie this relationship, linking HDL-C to triglyceride metabolism and atherosclerosis. In addition to free cholesterol, other surface components of TGRL, primarily phospholipids, are transferred to HDL during lipolysis. It remains indeterminate as to whether such transfer is linked to HDL-C and cardiovascular disease. Methods and results: When TGRL was labelled with fluorescent phospholipid 1,1?-dioctadecyl-3,3,3?,3?-tetramethylindocarbocyanine perchlorate (DiI), time- and dose-dependent transfer of DiI to HDL was observed upon incubations with lipoprotein lipase (LPL). The capacity of HDL to acquire DiI was decreased by -36% (p<0.001) in low HDL-C patients with acute myocardial infarction (n = 22) and by -95% (p<0.001) in low HDL-C subjects with Tangier disease (n = 7), unchanged in low HDL-C patients with Type 2 diabetes (n = 17) and in subjects with high HDL-C (n = 20), and elevated in subjects with extremely high HDL-C (+11%, p<0.05) relative to healthy normolipidemic controls. Across all the populations combined, HDL capacity to acquire DiI was directly correlated with HDL-C (r = 0.58, p<0.001). No relationship of HDL capacity to acquire DiI with both overall and cardiovascular mortality obtained from epidemiological studies for the mean HDL-C levels observed in the studied populations was obtained. Conclusions: These data indicate that the capacity of HDL to acquire phospholipid from TGRL upon LPL-mediated lipolysis is proportional to HDL-C and does not reflect cardiovascular risk in subjects widely differing in HDL-C levels.
  • conferenceObject
    The Challenge of Treating a Previously Surgical Revascularized Patient With Acute ST-Elevation Myocardial Infarction (STEMI) and Coronary- Subclavian Steal Syndrome
    (2021) PINESI, Henrique Trombini; MARINS, Pedro H.; BALZAN, Hadrien F.; HABRUM, Fabio Cetinic; MATUCK, Bruna R.; MEDEIROS, Marina A. de; PITTA, Fabio G.; LIMA, Eduardo G.; GARZILLO, Cibele L.; SERRANO, Carlos V.