CLAUDIA GOLDENSTEIN SCHAINBERG

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LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 10 de 38
  • conferenceObject
    Worse Mental Health In Employed Adult Patients With Juvenile Idiopathic Arthritis (JIA): More Than Just A Job
    (2013) AIKAWA, Nadia E.; GORDO, J. M. S.; KRIEGER, R.; PAULA, L. E.; GOLDENSTEIN-SCHAINBERG, Claudia
  • bookPart
    Vasculites na Infância
    (2018) PEREIRA, Rosa Maria Rodrigues; ASSAD, Ana Paula Luppino; GOLDENSTEIN-SCHAINBERG, Cláudia; AIKAWA, Nádia Emi
  • conferenceObject
    Behcet's Disease Activity: An Important Factor For Immunogenicity Of Unadjuvanted Influenza A/H1N1 Vaccine
    (2013) PRADO, Leandro L.; SAAD, Carla G. S.; MORAES, Julio C. B.; RIBEIRO, Ana Cristina Medeiros; AIKAWA, Nadia E.; SILVA, Clovis A.; SCHAINBERG, Claudia G.; SAMPAIO-BARROS, Percival D.; PRECIOSO, Alexander R.; ISHIDA, Maria A.; BONFA, Eloisa; GONCALVES, Celio
  • bookPart
    Artrite Idiopática Juvenil
    (2018) GOLDENSTEIN-SCHAINBERG, Cláudia; ASSAD, Ana Paula Luppino; AIKAWA, Nádia Emi; PEREIRA, Rosa Maria Rodrigues
  • conferenceObject
    EARLY SACROILIITIS AND PROGRESSION TO ANKYLOSING SPONDYLITIS IS ASSOCIATED TO POSITIVE HLA-B27 IN JUVENILE SPONDYLOARTHRITIS
    (2015) PEREZ, M. O.; AIKAWA, N. E.; CARRASCO, S.; SAAD, C. G.; SAMPAIO-BARROS, P. D.; GONCALVES, C. R.; MORAES, J. C. B.; GOLDENSTEIN-SCHAINBERG, C.
  • bookPart
    Lúpus eritematoso sistêmico juvenil
    (2021) AIKAWA, Nádia Emi; ASSAD, Ana Paula Luppino; SCHAINBERG, Cláudia Goldenstein; PEREIRA, Rosa Maria Rodrigues
  • bookPart
    Febre Reumática: Visão da Reumatologia
    (2016) SCHAINBERG, Cláudia Goldenstein; ASSAD, Ana Paula Luppino; AIKAWA, Nádia Emi; PEREIRA, Rosa Maria Rodrigues
  • article 1 Citação(ões) na Scopus
    Bone erosions associated with systemic bone loss on HR-pQCT in women with longstanding polyarticular juvenile idiopathic arthritis
    (2023) RIBEIRO, Surian Clarisse C. R.; SALES, Lucas P.; FERNANDES, Alan L.; PEREZ, Mariana O.; TAKAYAMA, Liliam; CAPARBO, Valeria F.; ASSAD, Ana Paula L.; AIWAKA, Nadia E.; GOLDENSTEIN-SCHAINBERG, Claudia; BORBA, Eduardo F.; DOMICIANO, Diogo S.; FIGUEIREDO, Camille P.; PEREIRA, Rosa M. R.
    Objectives: To analyze longstanding polyarticular juvenile idiopathic arthritis (pJIA) for possible associations between localized bone damage (erosions), and systemic bone loss. Besides, to compare the systemic bone mass of pJIA with healthy controls. Methods: Thirty-four pJIA women and 99 healthy controls (HC) were included. Radius and tibia of all subjects were scanned by HR-pQCT. Volumetric bone mineral density (vBMD), bone microarchitecture, and -finite element parameters were analyzed. Patients underwent HR-pQCT of 2nd and 3rd metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints of the dominant hand, for bone erosions quantification. Results: The mean age of patients was 31.5 +/- 7.4yrs with a mean disease duration of 21.7 +/- 9.2yrs. Bone erosions were detectable in 79% of patients. The number of bone erosions was positively correlated with cortical porosity (Ct.Po) at tibia (r = 0.575, p = 0.001), and radius (r = 0.423, p = 0.018); and negatively correlated with cortical vBMD at tibia (r=-0.420, p = 0.015). In a logistic regression analysis, adjusted for anti-CCP, the presence of bone erosions was independently associated with Ct.Po at radius (p = 0.018) and cortical vBMD at tibia (p = 0.020). Moreover, cortical and trabecular vBMD, trabecular number, and mu-finite element parameters were decreased in patients compared to HC (p < 0.05). Conclusion: Bone erosions in longstanding pJIA women were associated with decreased cortical bone parameters, and these patients showed systemic bone impairment at peripheral sites compared with healthy controls.
  • bookPart
    Esclerose Sistêmica Juvenil e Esclerodermia Localizada Juvenil
    (2018) ASSAD, Ana Paula Luppino; AIKAWA, Nádia Emi; GOLDENSTEIN-SCHAINBERG, Cláudia; PEREIRA, Rosa Maria Rodrigues
  • article 2 Citação(ões) na Scopus
    Hepatitis C virus antibodies in high risk juvenile onset systemic lupus erythematosus
    (2016) AIKAWA, Nadia E.; NASCIMENTO, Ana P.; HAYATA, Andre L. S.; BONFA, Eloisa; GOLDENSTEIN-SCHAINBERG, Claudia
    Objective: To evaluate the prevalence of hepatitis C virus (HCV) infection in high risk juvenile systemic lupus erythematosus (JSLE). Study design: Forty low income JSLE patients (6M:34F; mean age 19 +/- 4.4 yrs; mean disease duration 6 +/- 3.2 yrs) were studied. Twenty healthy children and adolescents matched for social economical level were included as controls. Anti-HCV tests were performed using a third generation microparticle enzyme immunoassay. Inclusion criterion was low social economical level. Results: The frequencies of anti-HCV antibody were low and comparable between JSLE and control group (2.5% vs. 0, p = 1.0). JSLE patients had significantly more risk factors for HCV infection compared to the control group, including immunosuppressive treatment (90% vs. 0, p < 0.0001), hospitalization (50% vs. 12.5%, p = 0.0006) and invasive procedures (47.5% vs. 12.5%, p = 0.001). Conclusions: The observed low frequency of anti-HCV antibodies in high risk JSLE suggests that this virus does not seem to have a relevant role in the pathogenesis of this disease.