CLAUDIA GOLDENSTEIN SCHAINBERG

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LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina

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  • conferenceObject
    Worse Mental Health In Employed Adult Patients With Juvenile Idiopathic Arthritis (JIA): More Than Just A Job
    (2013) AIKAWA, Nadia E.; GORDO, J. M. S.; KRIEGER, R.; PAULA, L. E.; GOLDENSTEIN-SCHAINBERG, Claudia
  • conferenceObject
    Behcet's Disease Activity: An Important Factor For Immunogenicity Of Unadjuvanted Influenza A/H1N1 Vaccine
    (2013) PRADO, Leandro L.; SAAD, Carla G. S.; MORAES, Julio C. B.; RIBEIRO, Ana Cristina Medeiros; AIKAWA, Nadia E.; SILVA, Clovis A.; SCHAINBERG, Claudia G.; SAMPAIO-BARROS, Percival D.; PRECIOSO, Alexander R.; ISHIDA, Maria A.; BONFA, Eloisa; GONCALVES, Celio
  • conferenceObject
    POSITIVE EFFECTS OF ANTI-MELANOCYTE STIMULATING HORMONE IN MURINE PRISTANE-INDUCED LUPUS
    (2013) PEIXOTO, T. V.; MELLO, S. B.; BOTTE, D. A.; CARRASCO, S.; VENDRAMINNI, M. B.; GOLDENSTEIN-SCHAINBERG, C.
  • conferenceObject
    EFFECTIVENESS OF LONG-TERM USE OF MINIMALIST FOOTWEAR ON PAIN AND FUNCTION IN KNEE OSTEOARTHRITIS
    (2013) GOLDENSTEIN-SCHAINBERG, Claudia; FULLER, Ricardo; MATIAS, Alessandra; YOKOTA, Mariane; BUTUGAN, Marco; TROMBINI-SOUZA, Francis; SACCO, Isabel
  • conferenceObject
    SPINAL LESIONS DUE TO TOPHACEOUS GOUT - A DIFFERENTIAL DIAGNOSIS NOT RELATED TO SYMPTOMS
    (2013) MELLO, F. M.; GOLDENSTEIN-SCHAINBERG, C.; FULLER, R.; HALPERN, A. S.
  • article 9 Citação(ões) na Scopus
    Increased prevalence of simple renal cysts in patients with gout
    (2013) HASEGAWA, Eduardo Massato; FULLER, Ricardo; CHAMMAS, Maria Cristina; MELLO, Filipe Martins de; GOLDENSTEIN-SCHAINBERG, Claudia
    The aim of this study was to determine the prevalence of simple renal cysts in gout patients and evaluate associated risk factors for its development. Hundred and forty-six patients followed at our outpatient Gout Unit and 47 sex- and age-matched healthy kidney donors who had undergone routine renal ultrasonography, using a static gray scale and real-time B-mode units with a 3.5- or 5.0-MHz transducer, were evaluated for the presence of renal cysts. Demographic and clinical characteristics of gout patients were evaluated considering possible risk factors for the occurrence of simple renal cysts such as age, male gender, hypertension, and renal impairment. The prevalence of simple renal cyst was 26.0 % in gout patients and 10.6 % in control group (P = 0.045). Gout patients with simple renal cysts presented less renal lithiasis than those without this complication (5.2 vs 25.9 %; P = 0.003) in spite of an overall higher frequency of renal stones in gout patients compared to control group (20.5 vs. 6.3 %, P = 0.025). The presence of simple renal cyst in gout was not associated with previously reported factors such as age (P = 0.296), male predominance (P = 0.688), hypertension (P = 0.314), and renal impairment (P = 254). Moreover, no association with disease duration (P = 0.843) or tophi (P = 0.616) was observed. In conclusion, gout patients have an increased prevalence of simple renal cysts associated with a lower occurrence of nephrolithiasis. Whether renal cysts have any protective effect in the development of nephrolithiasis in gout remains to be determined.
  • conferenceObject
    Cross-Cultural Adaptation, Validation and Reliability Of The Brazilian Version Of The Psoriatic Arthritis Screening Evaluation Tool
    (2013) RANZA, Roberto; SCHAINBERG, Claudia G.; CARNEIRO, Sueli; MARTINS, Gladys; RODRIGUES, Jose Joaquim; CARNEIRO, Jamille; ROMITI, Ricardo; BARROS, Thiago B. M.; SAMPAIO, Ana Luiza; PEDREIRA, Amanda; COSTA, Carolina Z.; PINTO, Rogerio M. C.; HUSNI, M. Elaine; QURESHI, Abrar A.
  • article 27 Citação(ões) na Scopus
    Effective seroconversion and safety following the pandemic influenza vaccination (anti-H1N1) in patients with juvenile idiopathic arthritis
    (2013) AIKAWA, N. E.; CAMPOS, L. M. A.; GOLDENSTEIN-SCHAINBERG, C.; SAAD, C. G. S.; RIBEIRO, A. C.; BUENO, C.; PRECIOSO, A. R.; TIMENETSKY, MdoC; SILVA, C. A. A.; BONFA, E.
    Objectives: To assess the vaccine response in juvenile idiopathic arthritis (JIA) as an extension of previous observation of immunogenicity and safety of a non-adjuvanted influenza A H1N1/2009 vaccine in a large population of juvenile rheumatic diseases. Moreover, to assess the possible influence of demographic data, disease subtypes, disease activity, and treatment on immunogenicity and the potential deleterious effect of the vaccine in the disease itself, particularly in the number of arthritis and inflammatory markers. Methods: A total of 95 patients with JIA and 91 healthy controls were evaluated before and 21 days after vaccination, and serology for anti-H1N1 was performed by haemagglutination inhibition assay (HIA). Patient and physician visual analogue scales (VAS), Childhood Health Assessment Questionnaire (CHAQ), number of active joints, acute phase reactants, and treatments were evaluated before and after vaccination. Adverse events were also reported. Results: JIA patients and controls were comparable regarding mean current age (14.9 +/- 3.2 vs. 14.6 +/- 3.7 years, p = 0.182). After vaccination, the seroconversion rate was significantly lower in JIA patients compared to controls (83.2% vs. 95.6%, p = 0.008), particularly in the polyarticular subtype (80% vs. 95.6%, p = 0.0098). Of note, JIA subtypes, number of active joints, acute phase reactants, CHAQ, patient and physician VAS, and use of disease-modifying anti-rheumatic drugs (DMARDs)/immunosuppressive drugs were similar between seroconverted and non-seroconverted patients (p > 0.05). Regarding vaccine safety, no deterioration was observed in the number of active joints and acute phase reactants during the study period. Conclusion: Influenza A H1N1/2009 vaccination in JIA induces a lower but effective protective antibody response probably independent of disease parameters and treatment with an adequate disease safety profile.
  • conferenceObject
    COLVa2 a Biomarker of Vasculopathy in Scleroderma?
    (2013) MORAIS, J.; MARTIN, P.; CAMARGO, I. C.; KATAYAMA, M. L.; CARRASCO, S.; GOLDEINSTEIN-SCHAINBERG, C.; PARRAS, E. R.; BARRENCE, F.; VELOSA, A. P.; CAPELOZZI, V. L.; TEODORA, W. R.
  • conferenceObject
    ABILITY OF COLLAGEN TYPE V IN IN VITRO DIFFERENTIATION OF RABBIT ADIPOSE TISSUE-DERIVED STEM CELLS INTO CHONDROCYTE-LIKE PHENOTYPE
    (2013) GOLDENSTEIN-SCHAINBERG, Claudia; FULLER, Ricardo; VELOSA, Paula; CARRASCO, Solange; CAPELOZZI, Vera; YOSHINARI, Natalino; TEODORO, Walcy; CRUZ, Isabele