JYMENEZ DE MORAIS
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conferenceObject INFLUENCE OF ALPHA 2 DO COLLAGEN V OVEREXPRESSION IN PHYSIOPHATOLOGY OF FIBROSIS SYSTEMIC SCLEROSIS PATIENTS(2014) MORAIS, J.; MARTIN, P.; VELOSA, A. P. P.; ANDRADE, P. C.; CRUZ, I. B.; MIRACCA, E. C.; FAC, F. A. C. Barrence; CARRASCO, S.; GOLDEINSTEIN-SCHAINBERG, C.; NAGAI, M. A.; PARRA, E. R.; CAPELOZZI, V. L.; TEODORO, W. R.conferenceObject ALTERED COLLAGEN FIBERS DEPOSITION IN SYNOVIAL JOINTS OF DIABETIC RATS' MODEL INDUCED BY STREPTOZOTOCIN(2014) GOLDENSTEIN-SCHAINBERG, C.; PARRA, E.; TEODORO, W. R.; CAPELOZZI, V. L.; ATAYDE, S. A.; MORAIS, J.; CATANOZI, S.; VELOSA, A. P.; ANDRADE, P. C.conferenceObject ALPHA2 (V) CHAIN AND COLVA2 INDUCES THE FIBRILLOGENESIS PROCESS IN DISTORTEDLUNG FRAMEWORK OF SYSTEMIC SCLEROSIS(2014) ANDRADE, P. C.; VELOSA, A. P. P.; MORAIS, J.; RANGEL, M. P.; CARRASCO, S.; CHISTMANN, R. B.; PARRA, E. R.; CAPELLOZZI, V. L.; TEODORO, W. R.- Effects of Maturation and Aging on the Pressure-Bearing Region of the Plantaris Longus Tendon of the Bullfrog (Lithobates catesbeianus)(2014) ZOREL, Valdenilson Jose; MORAIS, Jymenez De; ARO, Andrea Aparecida de; GOMES, Laurecir; ESQUISATTO, Marcelo Augusto MarrettoThe plantaris longus tendon (PLT) in bullfrog develops a fibrocartilage-like tissue in the area that is functionally subject to compressive forces. The aim of this study was to analyze the modifications of the pressure-bearing region in bullfrog PLT with different ages (7, 180, and 1,080 days after the end of metamorphosis) using histomorphometric, ultrastructural and biochemical methods. Weak basophilia and cells with a fibroblastic phenotype were observed in the compression region at 7 days of age. On the other hand, a large area of intense tissue basophilia associated with a chondroblast-like cell population was noted at the other ages. Collagen fibers exhibited a three-dimensional network-like arrangement at all ages. The number of connective tissue cells increased between 7 and 180 days of age and was reduced in older animals. The 180-day-old animals presented a well-developed pericellular matrix rich in proteoglycans. The mean diameter of collagen fibrils increased from 7 to 180 days and was the same at 1,080 days. Glycosaminoglycan content was higher in 7-day-old animals. A higher amount of hydroxyproline was observed at 180 and 1,080 days. The swelling test showed a significant increase of wet weight in 7-day-old animals. In conclusion, the alterations that occur in the pressure-bearing of bullfrog PLT are the result of physiological alterations of the animal with the maturation and aging. Microsc. Res. Tech. 77:797-805, 2014. (c) 2014 Wiley Periodicals, Inc.