RENATA DE FREITAS SAITO

(Fonte: Lattes)
Índice h a partir de 2011
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Lattes
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Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina
LIM/24 - Laboratório de Oncologia Experimental, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 3 de 3
  • article 21 Citação(ões) na Scopus
    Emerging targets for combination therapy in melanomas
    (2015) SAITO, Renata de Freitas; TORTELLI JR., Tharcisio Citrangulo; JACOMASSI, Mayara D'Auria; OTAKE, Andreia Hanada; CHAMMAS, Roger
    Cutaneous melanomas are often difficult to treat when diagnosed in advanced stages. Melanoma cells adapt to survive in extreme environmental conditions and are among the tumors with larger genomic instability. Here we discuss some intrinsic and extrinsic mechanisms of resistance of melanoma cells to both conventional and target therapies, such as autophagy, adaptation to endoplasmic reticulum stress, metabolic reprogramming, mechanisms of tumor repopulation and the role of extracellular vesicles in this later phenomenon. These biological processes are potentially targetable and thus provide a platform for research and discovery of new drugs for combination therapy to manage melanoma patient treatment.
  • bookPart
    O metabolismo da célula tumoral
    (2015) SAITO, Renata de Freitas; COLQUHOUN, Alison; CHAMMAS, Roger
  • bookPart
    Introdução ao câncer
    (2015) DIAZ, Ema Elissen Flores; SAITO, Renata de Freitas; CHAMMAS, Roger