MAURICIO DENER CORDEIRO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/55 - Laboratório de Urologia, Hospital das Clínicas, Faculdade de Medicina
LIM/55 - Laboratório de Urologia, Hospital das Clínicas, Faculdade de Medicina
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- Current concepts in multiparametric magnetic resonance imaging for active surveillance of prostate cancer(2018) CAVALCANTE, Alexandre; VIANA, Publio Cesar C.; GUGLIELMETTI, Giuliano B.; PONTES, Jose; NONEMACHER, Henrique; CORDEIRO, Mauricio D.; BEZERRA, Regis Otaviano F.; COELHO, Rafael F.; NAHAS, William Carlos
- Holmium Laser Resection of Large Bladder Tumors: Technique Description, Feasibility, and Histopathological Quality Analysis(2022) ISCAIFE, Alexandre; RIBEIRO FILHO, Leopoldo Alves; PEREIRA, Maikon Willian Aparecido; GALLUCCI, Fabio Pescarmona; CHADE, Daher; MURTA, Claudio Bovolenta; CORDEIRO, Mauricio Dener; CARDILI, Leonardo; SARKIS, Alvaro Sadeki; SROUGI, Miguel; NAHAS, William C.BACKGROUND The HoLERBT (Holmium Laser En-bloc Resection of Bladder Tumors) has emerged as an alternative to classical TURBT (Transurethral Resection of Bladder Tumor). Recent randomized trial and meta-analysis corroborate with the benefits in pathological analysis, perioperative and longterm oncological outcomes.(1-3) However, the treatment of large tumors and the technique of extraction from the bladder is a problem to be overcome.(1,4) OBJECTIVE To describe the laser resection of bladder tumors and demonstrate the feasibility of this procedure even for large tumors throughout a series of cases. It is also discussed the quality of the histopathological analysis. METHODS A series of 8 cases randomized selected to be the pilot for a trial comparing TURBT and HoLERBT in large tumors (>3 cm) in progress was analyzed (Brazilian Registry of Clinical Trials number RBR-67npwrk). The perioperative data and 1-year outcomes were assessed and the quality of histopathological analysis after morcellation was evaluated in terms of histopathology, grade, and stage. The entire procedure of one case is shown in a step-by-step video. RESULTS The mean follow-up was 12.6 months. The mean age was 59.6 (42-85) years, and the mean tumor size was 4.7 (4-8) cm. All the resections were En-bloc. There were 2 cases of NMIBC, 4 cases of MIBC, 1 paraganglioma, and 1 adenocarcinoma. The histopathological analysis confirmed the presence of detrusor muscle layer and accurate diagnosis and staging in all cases (100%). There were no perioperative Clavien-Dindo > 1 complications, no blood transfusion, and no bladder perforations. The histopathology analysis reveals excellent quality without artifacts of fulguration. CONCLUSION The holmium laser resection followed by morcellation of large bladder tumors is a feasible procedure. No complications occurred in our series of cases and all cases provided excellent material for histopathological analysis. (C) 2022 Elsevier Inc.
- Robot-assisted laparoscopic radical prostatectomy with early retrograde release of the neurovascular bundle and endopelvic fascia sparing(2017) ALBUQUERQUE, George Augusto Monteiro Lins de; GUGLIELMETTI, Giuliano Betoni; CORDEIRO, Mauricio Dener; NAHAS, William Carlos; COELHO, Rafael FerreiraIntroduction: Robotic-assisted radical prostatectomy (RAP) is the dominant minimally invasive surgical treatment for patients with localized prostate cancer. The introduction of robotic assistance has the potential to improve surgical outcomes and reduce the steep learning curve associated with conventional laparoscopic radical prostatectomy. The purpose of this video is to demonstrate the early retrograde release of the neurovascular bundle without open the endopelvic fascia during RAP. Materials and Methods: A 51-year old male, presenting histological diagnosis of prostate adenocarcinoma, Gleason 6 (3+3), in 4 cores of 12, with an initial PSA=3.41ng/dl and the digital rectal examination demonstrating a prostate with hardened nodule in the right lobe of the prostate base (clinical stage T2a). Surgical treatment with the robot-assisted technique was offered as initial therapeutic option and the critical technical point was the early retrograde release of the neurovascular bundle with endopelvic fascia preservation, during radical prostatectomy. Results: The operative time was of 89 minutes, blood loss was 100ml. No drain was left in the peritoneal cavity. The patient was discharged within 24 hours. There were no intraoperative or immediate postoperative complications. The pathological evaluation revealed prostate adenocarcinoma, Gleason 6, with free surgical margins and seminal vesicles free of neoplastic involvement (pathologic stage T2a). At 3-month-follow-up, the patient lies with undetectable PSA, continent and potent. Conclusion: This is a feasible technique combining the benefits of retrograde release of the neurovascular bundle, the preservation of the pubo-prostatic collar and the preservation of the antero-lateral cavernous nerves.
- Impact of COVID-19 on a urology residency program(2021) DANILOVIC, Alexandre; TORRICELLI, Fabio Cesar Miranda; ANJOS, Gabriel dos; CORDEIRO, Mauricio Dener; MACHADO, Marcos Giannetti; SROUGI, Miguel; NAHAS, William C.