FRANCISCO CARLOS DA COSTA DARRIEUX

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Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico

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  • article 15 Citação(ões) na Scopus
    European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: What is the best practice?
    (2018) DAGRES, Nikolaos; CHAO, Tze-Fan; FENELON, Guilherme; AGUINAGA, Luis; BENHAYON, Daniel; BENJAMIN, Emelia J.; BUNCH, T. Jared; CHEN, Lin Yee; CHEN, Shih-Ann; DARRIEUX, Francisco; PAOLA, Angelo de; FAUCHIER, Laurent; GOETTE, Andreas; KALMAN, Jonathan; KALRA, Lalit; KIM, Young-Hoon; LANE, Deirdre A.; LIP, Gregory Y. H.; LUBITZ, Steven A.; MARQUEZ, Manlio F.; POTPARA, Tatjana; POZZER, Domingo Luis; RUSKIN, Jeremy N.; SAVELIEVA, Irina; TEO, Wee Siong; TSE, Hung-Fat; VERMA, Atul; ZHANG, Shu; CHUNG, Mina K.
  • article 157 Citação(ões) na Scopus
    2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy: Executive summary
    (2019) TOWBIN, Jeffrey A.; MCKENNA, William J.; ABRAMS, Dominic J.; ACKERMAN, Michael J.; CALKINS, Hugh; DARRIEUX, Francisco C. C.; DAUBERT, James P.; CHILLOU, Christian de; DEPASQUALE, Eugene C.; DESAI, Milind Y.; III, N. A. Mark Estes; HUA, Wei; INDIK, Julia H.; INGLES, Jodie; JAMES, Cynthia A.; JOHN, Roy M.; JUDGE, Daniel P.; KEEGAN, Roberto; KRAHN, Andrew D.; LINK, Mark S.; MARCUS, Frank I.; MCLEOD, Christopher J.; MESTRONI, Luisa; PRIORI, Silvia G.; SAFFITZ, Jeffrey E.; SANATANI, Shubhayan; SHIMIZU, Wataru; TINTELEN, J. Peter van; WILDE, Arthur A. M.; ZAREBA, Wojciech
    Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a broad spectrum of genetic, systemic, infectious, and inflammatory disorders. This designation includes, but is not limited to, arrhythmogenic right/left ventricular cardiomyopathy, cardiac amyloidosis, sarcoidosis, Chagas disease, and left ventricular noncompaction. The ACM phenotype overlaps with other cardiomyopathies, particularly dilated cardiomyopathy with arrhythmia presentation that may be associated with ventricular dilatation and/or impaired systolic function. This expert consensus statement provides the clinician with guidance on evaluation and management of ACM and includes clinically relevant information on genetics and disease mechanisms. PICO questions were utilized to evaluate contemporary evidence and provide clinical guidance related to exercise in arrhythmogenic right ventricular cardiomyopathy. Recommendations were developed and approved by an expert writing group, after a systematic literature search with evidence tables, and discussion of their own clinical experience, to present the current knowledge in the field. Each recommendation is presented using the Class of Recommendation and Level of Evidence system formulated by the American College of Cardiology and the American Heart Association and is accompanied by references and explanatory text to provide essential context. The ongoing recognition of the genetic basis of ACM provides the opportunity to examine the diverse triggers and potential common pathway for the development of disease and arrhythmia.
  • article 23 Citação(ões) na Scopus
    European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases
    (2022) WILDE, Arthur A. M.; SEMSARIAN, Christopher; MARQUEZ, Manlio F.; SHAMLOO, Alireza Sepehri; ACKERMAN, Michael J.; ASHLEY, Euan A.; EDUARDO, Back Sternick; BARAJAS-MARTINEZ, Hector; BEHR, Elijah R.; BEZZINA, Connie R.; BRECKPOT, Jeroen; CHARRON, Philippe; CHOCKALINGAM, Priya; CROTTI, Lia; GOLLOB, Michael H.; LUBITZ, Steven; MAKITA, Naomasa; OHNO, Seiko; ORTIZ-GENGA, Martin; SACILOTTO, Luciana; SCHULZE-BAHR, Eric; SHIMIZU, Wataru; SOTOODEHNIA, Nona; TADROS, Rafik; WARE, James S.; WINLAW, David S.; KAUFMAN, Elizabeth S.; AIBA, Takeshi; BOLLMANN, Andreas; CHOI, Jong-Il; DALAL, Aarti; DARRIEUX, Francisco; GIUDICESSI, John; GUERCHICOFF, Mariana; HONG, Kui; KRAHN, Andrew D.; INTYRE, Ciorsti Mac; MACKALL, Judith A.; MONT, Lluis; NAPOLITANO, Carlo; JUAN, Pablo Ochoa; PEICHL, Petr; PEREIRA, Alexandre C.; SCHWARTZ, Peter J.; SKINNER, Jon; STELLBRINK, Christoph; TFELT-HANSEN, Jacob; DENEKE, Thomas
  • article 77 Citação(ões) na Scopus
    European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases
    (2022) WILDE, Arthur A. M.; SEMSARIAN, Christopher; MARQUEZ, Manlio F.; SHAMLOO, Alireza Sepehri; ACKERMAN, Michael J.; ASHLEY, Euan A.; STERNICK, Eduardo Back; BARAJAS-MARTINEZ, Hector; BEHR, Elijah R.; BEZZINA, Connie R.; BRECKPOT, Jeroen; CHARRON, Philippe; CHOCKALINGAM, Priya; CROTTI, Lia; GOLLOB, Michael H.; LUBITZ, Steven; MAKITA, Naomasa; OHNO, Seiko; ORTIZ-GENGA, Martin; SACILOTTO, Luciana; SCHULZE-BAHR, Eric; SHIMIZU, Wataru; SOTOODEHNIA, Nona; TADROS, Rafik; WARE, James S.; WINLAW, David S.; KAUFMAN, Elizabeth S.; AIBA, Takeshi; BOLLMANN, Andreas; CHOI, Jong-Il; DALAL, Aarti; DARRIEUX, Francisco; GIUDICESSI, John; GUERCHICOFF, Mariana; HONG, Kui; KRAHN, Andrew D.; MACINTYRE, Ciorsti; MACKALL, Judith A.; MONT, Lluis; NAPOLITANO, Carlo; OCHOA, Juan Pablo; PEICHL, Petr; PEREIRA, Alexandre C.; SCHWARTZ, Peter J.; SKINNER, Jon; STELLBRINK, Christoph; TFELT-HANSEN, Jacob; DENEKE, Thomas
  • article 46 Citação(ões) na Scopus
    A Primary Prevention Clinical Risk Score Model for Patients With Brugada Syndrome (BRUGADA-RISK)
    (2021) HONARBAKHSH, Shohreh; PROVIDENCIA, Rui; GARCIA-HERNANDEZ, Jorge; MARTIN, Claire A.; HUNTER, Ross J.; LIM, Wei Y.; KIRKBY, Claire; GRAHAM, Adam J.; SHARIFZADEHGAN, Ardalan; WALDMANN, Victor; MARIJON, Eloi; MUNOZ-ESPARZA, Carmen; LACUNZA, Javier; GIMENO-BLANES, Juan Ramon; ANKOU, Benedicte; CHEVALIER, Philippe; ANTONIO, Natalia; ELVAS, Luis; CASTELLETTI, Silvia; CROTTI, Lia; SCHWARTZ, Peter; SCANAVACCA, Mauricio; DARRIEUX, Francisco; SACILOTTO, Luciana; MUELLER-LEISSE, Johanna; VELTMANN, Christian; VICENTINI, Alessandro; DEMARCHI, Andrea; CORTEZ-DIAS, Nuno; ANTONIO, Pedro Silverio; SOUSA, Joao de; ADRAGAO, Pedro; CAVACO, Diogo; COSTA, Francisco Morosco; KHOUEIRY, Ziad; BOVEDA, Serge; SOUSA, Mario Joao; JEBBERI, Zeynab; HECK, Patrick; MEHTA, Sarju; CONTE, Giulio; OZKARTAL, Tardu; AURICCHIO, Angelo; LOWE, Martin D.; SCHILLING, Richard J.; PRIETO-MERINO, David; LAMBIASE, Pier D.
    OBJECTIVES The goal of this study was to develop a risk score model for patients with Brugada syndrome (BrS). BACKGROUND Risk stratification in BrS is a significant challenge due to the low event rates and conflicting evidence. METHODS A multicenter international cohort of patients with BrS and no previous cardiac arrest was used to evaluate the role of 16 proposed clinical or electrocardiogram (ECG) markers in predicting ventricular arrhythmias (VAs)/sudden cardiac death (SCD) during follow-up. Predictive markers were incorporated into a risk score model, and this model was validated by using out-of-sample cross-validation. RESULTS A total of 1,110 patients with BrS from 16 centers in 8 countries were included (mean age 51.8 +/- 13.6 years; 71.8% male). Median follow-up was 5.33 years; 114 patients had VA/SCD (10.3%) with an annual event rate of 1.5%. Of the 16 proposed risk factors, probable arrhythmia-related syncope (hazard ratio [HR]: 3.71; p < 0.001), spontaneous type 1 ECG (HR: 3.80; p < 0.001), early repolarization (HR: 3.42; p < 0.001), and a type 1 Brugada ECG pattern in peripheral leads (HR: 2.33; p < 0.001) were associated with a higher risk of VA/SCD. A risk score model incorporating these factors revealed a sensitivity of 71.2% (95% confidence interval: 61.5% to 84.6%) and a specificity of 80.2% (95% confidence interval: 75.7% to 82.3%) in predicting VA/SCD at 5 years. Calibration plots showed a mean prediction error of 1.2%. The model was effectively validated by using out-of-sample cross-validation according to country. CONCLUSIONS This multicenter study identified 4 risk factors for VA/SCD in a primary prevention BrS population. A risk score model was generated to quantify risk of VA/SCD in BrS and inform implantable cardioverter-defibrillator prescription. (C) 2021 The Authors.
  • article 436 Citação(ões) na Scopus
    2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy
    (2019) TOWBIN, Jeffrey A.; MCKENNA, William J.; ABRAMS, Dominic J.; ACKERMAN, Michael J.; CALKINS, Hugh; DARRIEUX, Francisco C. C.; DAUBERT, James P.; CHILLOU, Christian de; DEPASQUALE, Eugene C.; DESAI, Milind Y.; III, N. A. Mark Estes; HUA, Wei; INDIK, Julia H.; INGLES, Jodie; JAMES, Cynthia A.; JOHN, Roy M.; JUDGE, Daniel P.; KEEGAN, Roberto; KRAHN, Andrew D.; LINK, Mark S.; MARCUS, Frank I.; MCLEOD, Christopher J.; MESTRONI, Luisa; PRIORI, Silvia G.; SAFFITZ, Jeffrey E.; SANATANI, Shubhayan; SHIMIZU, Wataru; TINTELEN, J. Peter van; WILDE, Arthur A. M.; ZAREBA, Wojciech
    Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a broad spectrum of genetic, systemic, infectious, and inflammatory disorders. This designation includes, but is not limited to, arrhythmogenic right/left ventricular cardiomyopathy, cardiac amyloidosis, sarcoidosis, Chagas disease, and left ventricular noncompaction. The ACM phenotype overlaps with other cardiomyopathies, particularly dilated cardiomyopathy with arrhythmia presentation that may be associated with ventricular dilatation and/or impaired systolic function. This expert consensus statement provides the clinician with guidance on evaluation and management of ACM and includes clinically relevant information on genetics and disease mechanisms. PICO questions were utilized to evaluate contemporary evidence and provide clinical guidance related to exercise in arrhythmogenic right ventricular cardiomyopathy. Recommendations were developed and approved by an expert writing group, after a systematic literature search with evidence tables, and discussion of their own clinical experience, to present the current knowledge in the field. Each recommendation is presented using the Class of Recommendation and Level of Evidence system formulated by the American College of Cardiology and the American Heart Association and is accompanied by references and explanatory text to provide essential context. The ongoing recognition of the genetic basis of ACM provides the opportunity to examine the diverse triggers and potential common pathway for the development of disease and arrhythmia.
  • article 70 Citação(ões) na Scopus
    European Heart RhythmAssociation (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on arrhythmias and cognitive function: what is the best practice?
    (2018) DAGRES, Nikolaos; CHAO, Tze-Fan; FENELON, Guilherme; AGUINAGA, Luis; BENHAYON, Daniel; BENJAMIN, Emelia J.; BUNCH, T. Jared; CHEN, Lin Yee; CHEN, Shih-Ann; DARRIEUX, Francisco; PAOLA, Angelo de; FAUCHIER, Laurent; GOETTE, Andreas; KALMAN, Jonathan; KALRA, Lalit; KIM, Young-Hoon; LANE, Deirdre A.; LIP, Gregory Y. H.; LUBITZ, Steven A.; MARQUEZ, Manlio F.; POTPARA, Tatjana; POZZER, Domingo Luis; RUSKIN, Jeremy N.; SAVELIEVA, Irina; TEO, Wee Siong; TSE, Hung-Fat; VERMA, Atul; ZHANG, Shu; CHUNG, Mina K.; BAUTISTA-VARGAS, William-Fernando; CHIANG, Chern-En; CUESTA, Alejandro; DAN, Gheorghe-Andrei; FRANKEL, David S.; GUO, Yutao; HATALA, Robert; LEE, Young Soo; MURAKAWA, Yuji; PELLEGRINI, Cara N.; PINHO, Claudio; MILAN, David J.; MORIN, Daniel P.; NADALIN, Elenir; NTAIOS, George; PRABHU, Mukund A.; PROIETTI, Marco; RIVARD, Lena; VALENTINO, Mariana; SHANTSILA, Alena