PEDRO FRANCISCO GIAVINA-BIANCHI JUNIOR
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Clínica Médica, Faculdade de Medicina - Docente
LIM/60 - Laboratório de Imunologia Clínica e Alergia, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/60 - Laboratório de Imunologia Clínica e Alergia, Hospital das Clínicas, Faculdade de Medicina - Líder
18 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 18
- Drug-induced anaphylaxis: is it an epidemic?(2018) GIAVINA-BIANCHI, Pedro; AUN, Marcelo V.; KALIL, JorgePurpose of reviewThe present review addresses the epidemiology, analyzes the current data and promotes global awareness of drug-induced anaphylaxis.Recent findingsAnaphylaxis is a medical emergency that may cause death! In the last decade, studies have shown an increasing incidence and prevalence of anaphylaxis.SummaryDrug-induced anaphylaxis fatalities have increased, and this syndrome remains underdiagnosed and undertreated.
conferenceObject Inhaled corticoids in asthmatic patients: effect on body mass index and spirometry(2018) PACHECO, Rosilane dos Reis; ANDRADE, Mayra Coutinho; PEDROSO, Natalia Falci; TAKEJIMA, Priscila; AUN, Marcelo V.; KALIL FILHO, Jorge Elias; GIAVINA-BIANCHI, Pedro; AGONDI, Rosana C.conferenceObject Frequency Of Anti-inflammatory Related Cutaneous Manifestation In Patients With Aspirin-exacerbated Respiratory Disease (AERD)(2018) ANDRADE, Mayra Coutinho; PACHECO, Rosilane dos Reis; ALMEIDA, Mila; TAKEJIMA, Priscila; KALIL FILHO, Jorge Elias; GIAVINA-BIANCHI, Pedro; AGONDI, Rosana C.conferenceObject Case report of severe anaphylaxis induced by morphine and tramadol(2018) BRUGNOLLI, R. M.; PEREIRA, A. R. F.; KALIL, J.; MOTTA, A. A.; V, M. Aun; GIAVINA-BIANCHI, P.- Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions(2018) GARRO, Laila S.; V, Marcelo Aun; SOARES, Iracy Silvia C.; RIBEIRO, Marisa R.; MOTTA, Antonio A.; KALIL, Jorge; CASTELLS, Mariana C.; CARMONA, Maria Jose C.; GIAVINA-BIANCHI, PedroOBJECTIVE: To assess the incidence of intra-operative immediate hypersensitivity reactions and anaphylaxis. METHODS: A cross-sectional observational study was conducted at the Department of Anesthesiology, University of Sao Paulo School of Medicine, Hospital das Clinicas, Sao Paulo, Brazil, from January to December 2010. We developed a specific questionnaire to be completed by anesthesiologists. This tool included questions about hypersensitivity reactions during anesthesia and provided treatments. We included patients with clinical signs compatible with immediate hypersensitivity reactions. Hhypersensitivity reactions were categorized according to severity (grades I-V). American Society of Anesthesiologists physical status classification (ASA 1-6) was analyzed and associated with the severity of hypersensitivity reactions. RESULTS: In 2010, 21,464 surgeries were performed under general anesthesia. Anesthesiologists answered questionnaires on 5,414 procedures (25.2%). Sixty cases of intra-operative hypersensitivity reactions were reported. The majority patients (45, 75%) had hypersensitivity reactions grade I reactions (incidence of 27.9:10,000). Fifteen patients (25%) had grade II, III or IV reactions (intra-operative anaphylaxis) (incidence of 7:10,000). No patients had grade V reactions. Thirty patients (50%) were classified as ASA 1. The frequency of cardiovascular shock was higher in patients classified as ASA 3 than in patients classified as ASA 1 or ASA 2. Epinephrine was administered in 20% of patients with grade III hypersensitivity reactions and in 50% of patients with grade II hypersensitivity reactions. CONCLUSIONS: The majority of patients had hypersensitivity reactions grade I reactions; however, the incidence of intra-operative anaphylaxis was higher than that previously reported in the literature. Patients with ASA 3 had more severe anaphylaxis; however, the use of epinephrine was not prescribed in all of these cases. Allergists and anesthesiologists should implement preventive measures to reduce the occurrence of anaphylaxis.
- Intravenous Immunoglobulin May Be Beneficial as an Add-on Therapy in DRESS(2018) GIAVINA-BIANCHI, Pedro; HUANG, Shih-Wen
- Brazilian Guidelines for Hereditary Angioedema Management-2017 Update Part 1: Definition, Classification and Diagnosis(2018) GIAVINA-BIANCHI, Pedro; ARRUDA, Luisa Karla; AUN, Marcelo V.; CAMPOS, Regis A.; CHONG-NETO, Herberto J.; CONSTANTINO-SILVA, Rosemeire N.; FERNANDES, Fatima R.; FERRARO, Maria F.; FERRIANI, Mariana P. L.; FRANCA, Alfeu T.; FUSARO, Gustavo; GARCIA, Juliana F. B.; KOMNINAKIS, Shirley; MAIA, Luana S. M.; MANSOUR, Eli; MORENO, Adriana S.; MOTTA, Antonio A.; PESQUERO, Joao B.; PORTILHO, Nathalia; ROSARIO, Nelson A.; SERPA, Faradiba S.; SOLE, Dirceu; TAKEJIMA, Priscila; TOLEDO, Eliana; VALLE, Solange O. R.; VERONEZ, Camila L.; GRUMACH, Anete S.Hereditary angioedema is an autosomal dominant disease characterized by recurrent angioedema attacks with the involvement of multiple organs. The disease is unknown to many health professionals and is therefore underdiagnosed. Patients who are not adequately diagnosed and treated have an estimated mortality rate ranging from 25% to 40% due to asphyxiation by laryngeal angioedema. Intestinal angioedema is another important and incapacitating presentation that may be the main or only manifestation during an attack. In this article, a group of experts from the ""Associacao Brasileira de Alergia e Imunologia (ASBAI)'' and the ""Grupo de Estudos Brasileiro em Angioedema Hereditario (GEBRAEH)'' has updated the Brazilian guidelines for the diagnosis and treatment of hereditary angioedema.
- Improving the Management of Hereditary Angioedema(2018) GIAVINA-BIANCHI, Pedro; KALIL, Jorge
- Use of pdC1-INH concentrate for long-term prophylaxis during pregnancy in hereditary angioedema with normal C1-INH(2018) GARCIA, Juliana F. B.; TAKEJIMA, Priscila; VERONEZ, Camila Lopes; AUN, Marcelo V.; MOTTA, Antonio A.; KALIL, Jorge; PESQUERO, Joao Bosco; GIAVINA-BIANCHI, Pedro
conferenceObject Midazolam is a major cause of intraoperative immediate hypersensitivity reactions(2018) D'ONOFRIO, Ana Carolina; BORALLI, Cristiane Fernandes; PORTILHO, Nathalia Coelho; GARRO, Laila Sabino; RIBEIRO, Marisa Rosimeire; MAGALHAES, Manoela Crespo De; CAMPOS, Lucila; MOTTA, Antonio Abilio; KALIL FILHO, Jorge Elias; GIAVINA-BIANCHI, Pedro; AUN, Marcelo V.