VITOR MANOEL SILVA DOS REIS

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Departamento de Dermatologia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/56 - Laboratório de Investigação em Dermatologia e Imunodeficiências, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 10 de 24
  • conferenceObject
    Amicrobial pustulosis of the folds: Report of case successfully treated with doxycycline
    (2017) AMED FILHO, Abes; WU, Isabelle; LEE, Desiree Ji Re; ORLANDI, Renata; REIS, Vitor; ARNONE, Marcelo
  • article 8 Citação(ões) na Scopus
    Psoriasiform mucositis on the gingival and palatal mucosae treated with retinoic-acid mouthwash
    (2013) REIS, Vitor; ARTICO, Gabriela; SEO, Juliana; BRUNO, Ingrid; HIROTA, Silvio K.; LEMOS JR., Celso; MARTINS, Marilia; MIGLIARI, Dante
  • article 13 Citação(ões) na Scopus
    Tungiasis under dermoscopy: in vivo and ex vivo examination of the cutaneous infestation due to Tunga penetrans
    (2013) CRIADO, Paulo Ricardo; LANDMAN, Gilles; REIS, Vitor Manoel Silva dos; BELDA JUNIOR, Walter
    The female flea Tunga penetrans is responsible for a cutaneous parasitosis known as Tungiasis. We report the clinical case of a 12 year-old Caucasian boy who sought treatment in a dermatological private office due to a painful lesion in the plantar area and whose dermoscopic examination, without skin contact, allowed the visualization of parasite's movement inside the skin. The diagnosis of tungiasis is clinical, but it can be aided by in vivo and ex vivo dermoscopic examination of the lesion.
  • article 30 Citação(ões) na Scopus
    Evaluation of D-dimer serum levels among patients with chronic urticaria, psoriasis and urticarial vasculitis
    (2013) CRIADO, Paulo Ricardo; ANTINORI, Lidi Che Leon; MARUTA, Celina Wakisaka; REIS, Vitor Manoel Silva dos
    BACKGROUND: It has been demonstrated that neutrophils, eosinophils and monocytes, under appropriated stimulus, may express tissue factor and therefore, activate the extrinsic pathway of coagulation. We performed a transversal and case-control study of patients with chronic urticaria and patients with psoriasis, in our outpatient clinic to evaluate the production of D-dimer. OBJECTIVE: To evaluate D-dimer serum levels in patients with chronic urticaria and its possible correlation with disease activity. PATIENTS AND METHODS: The study was conducted from October 2010 until March 2011. We selected 37 consecutive patients from our Allergy Unit and Psoriasis Unit, and divided them into three groups for statistical analysis: (i) 12 patients with active chronic urticaria (CU); (ii) 10 patients with chronic urticaria under remission and (iii) 15 patients with psoriasis (a disease with skin inflammatory infiltrate constituted by neutrophils, lymphocytes and monocytes). Another five patients with urticarial vasculitis were allocated in our study, but not included in statistical analysis. The serum levels of D-dimer were measured by Enzyme Linked Fluorescent Assay (ELFA), and the result units were given in ng/ml FEU. RESULTS: Patients with active chronic urticaria had the highest serum levels of D-dimer (p<0.01), when compared to patients with CU under remission and the control group (patients with psoriasis). CONCLUSIONS: Patients with active chronic urticaria have higher serum levels of D-dimer, when compared to patients with chronic urticaria under remission and patients with psoriasis. We found elevated serum levels of D-dimer among patients with urticarial vasculitis.
  • article 4 Citação(ões) na Scopus
    Evolução histórica dos Anais Brasileiros de Dermatologia
    (2012) COSTA, Izelda Maria Carvalho; VALLARELLI, Andrelou Fralete Ayres; BONAMIGO, Renan Rangel; REIS, Vitor Manoel da Silva
    In this special edition in celebration of the centennial of the Brazilian Society of Dermatology, the authors take a retrospective look at printed Brazilian dermatology from the very beginning onward, showing evidence of descriptive dermatology with rich discussions, illustrations and advertisements of medications much used at the time, such as bismuth for the treatment of syphilis, before the discovery of penicillin. This retrospective covers up to the current days, when publications in the Brazilian Annals of Dermatology have reached the modern era in electronics, science and layout as well.
  • article 1 Citação(ões) na Scopus
    Experience in management of porphyria cutanea tarda in a tertiary referral Brazilian hospital from 2002 to 2017
    (2019) ARTEAGA, Julia Elisa Cabezas; VIEIRA, Fatima Mendonca Jorge; REIS, Vitor Manoel Silva dos
    Background Porphyria cutanea tarda (PCT) is the most common porphyria worldwide. The known acquired precipitating factors that induce PCT include alcoholism, hepatitis C virus infection, human immunodeficiency virus infection, and estrogen intake. Hereditary hemochromatosis is considered an inherited risk factor. The aim of this study was to describe and analyze precipitating factors and family history, with emphasis on PCT management. Methods A retrospective study of 87 patients with PCT was conducted between January 2002 and December 2017. Results A male predominance of 1.8 : 1 was found. The median age at diagnosis was 49 years (range 18-71). Family history of PCT was observed in 19.5% of patients. Two or more acquired precipitating factors were present in 42.5%. Patients were treated with antimalarial monotherapy (72.4%), antimalarial combined with phlebotomy (22.9%), and only with phlebotomy (4.6%). Acquired precipitating factors and inherited factors were not associated with treatment group. There was a difference in 24 h-UP normalization rate between treatment groups; combined therapy takes longer than antimalarial monotherapy, 38 months versus 15 months, respectively (CI 95%, 6.5-63.5 vs. 12.9-17) (log-rank test, P = 0.004). Conclusion Precipitating factors did not seem to be associated with treatment choice; however, all acquired and inherited precipitating factors should be investigated, and the choice between phlebotomy and/or antimalarials should be individualized. All dermatologists treating PCT patients should observe transferrin saturation and ferritin levels to search for underlying hereditary hemochromatosis.
  • article 13 Citação(ões) na Scopus
    Evaluation of the profile of inflammatory cytokines, through immunohistochemistry, in the skin of patients with allergic contact dermatitis to nickel in the acute and chronic phases
    (2018) SILVESTRE, Marilene Chaves; REIS, Vitor Manoel Silva dos
    BACKGROUND: Allergic contact dermatitis to ion nickel (Ni+2) is an inflammatory dermatosis, common in industrialized countries. It involves the activation of nickel-specific T-cells, followed by proliferation and induction of a mixed profile of both proinflammatory and regulatory cytokines, suggesting that several T-cell subtypes (helper - Th and cytotoxic - Tc) are involved. A broader understanding of the cytokine profile may lead to new therapeutic approaches. OBJECTIVES: This study aimed to analyze the cytokines TNF-alpha, INIF-gamma, IL-2, IL-4, IL-10, IL-13, IL-17 and IL-23 using the inununohistochemistry technique in order to try to identify their prevalence in chronic and acute eczema of patients with allergic contact dermatitis to Ni+2. METHODS: We performed an immunohistochemical study for eight cytokines in 20 patients with Ni+2 allergic contact dermatitis, biopsied at the site of chronic eczema, triggered by the patient's daily contact with Ni+2, and at the site of acute eczema caused by nickel sulfate, 48 hours after applying the contact test. RESULTS: The stained samples showed positive results for the eight cytokines studied. TNF-alpha, IFN-gamma, IL-4, IL-13 and IL-17 had a higher prevalence in chronic eczema, IL-2 and IL-23 in acute eczema, and IL-10 presented a similar prevalence in both acute and chronic eczema. However, these prevalences were statistically significant only for IL-4 and IL-13. STUDY LIMITATIONS: Small sample size. CONCLUSIONS: In chronic and acute eczema, we observed the presence of a mixed cytokine profile of the T cell subtypes (Th/Tc), suggesting that the responses are expressed at the same time.
  • article 29 Citação(ões) na Scopus
    Chronic urticaria in adults: state-of-the-art in the new millennium
    (2015) CRIADO, Paulo Ricardo; MARUTA, Celina Wakisaka; CRIADO, Roberta Facchini Jardim; REIS, Vitor Manoel Silva dos
    Chronic urticaria has been explored in several investigative aspects in the new millennium, either as to its pathogenesis, its stand as an autoimmune or auto-reactive disease, the correlation with HLA-linked genetic factors, especially with class II or its interrelation with the coagulation and fibrinolysis systems. New second-generation antihistamines, which act as good symptomatic drugs, emerged and were commercialized over the last decade. Old and new drugs that may interfere with the pathophysiology of the disease, such as cyclosporine and omalizumab have been developed and used as treatments. The purpose of this article is to describe the current state of knowledge on aspects of chronic urticaria such as, pathophysiology, diagnosis and the current therapeutic approach proposed in the literature.
  • article 11 Citação(ões) na Scopus
    Dermatomyositis: analysis of 109 patients surveyed at the Hospital das Clinicas (HCFMUSP), Sao Paulo, Brazil
    (2014) ORTIGOSA, Luciena Cegatto Martins; REIS, Vitor Manuel Silva dos
    BACKGROUND: Dermatomyositis affects striated muscles, skin and other organs. OBJECTIVE: To characterize the disease from January 1992 to December 2002, assessing its classification, cutaneous and systemic manifestations, and also laboratory results, therapeutic and prognostic findings compared to those in the literature. METHODS: Data were obtained from medical records of 109 patients who were classified into five groups: 23 juvenile dermatomyositis; 59 primary idiopathic dermatomyositis; 6 amyopathic dermatomyositis; 7 dermatomyositis associated with neoplasms and 14 dermatomyositis associated with other connective tissue diseases. RESULTS: Sixty patients were classified as ""definite"" diagnosis; 33 as ""possible""; four as ""probable"" and 12 and as amyopathic. The average age at diagnosis was 36 years. Cutaneous manifestations occurred in all patients; the most frequent symptom was loss of proximal muscle strength; the most common pulmonary disorder was interstitial lung disease, and gastritis was the most prevalent digestive manifestation. Tumors were documented in 6.42% of cases. Lactate dehydrogenase was the muscle enzyme most frequently elevated in the majority of cases. Skin biopsies were performed in 68 patients; muscle biopsies in 53; and electroneuromyographies in 58 patients. The most commonly used treatment was corticotherapy and the mortality rate was 14.7%. CONCLUSION: in this sample, the disease appeared in younger individuals, was more frequent in women and the association with cancer was small.
  • article 28 Citação(ões) na Scopus
    Immunopathology of allergic contact dermatitis
    (2011) MARTINS, Luis Eduardo Agner Machado; REIS, Vitor Manoel Silva dos
    Allergic contact dermatitis is the consequence of an immune reaction mediated by T cells against low molecular weight chemicals known as haptens. It is a common condition that occurs in all races and age groups and affects the quality of life of those who present it. The immunological mechanism of this disease has been reviewed in recent decades with significant advance in its understanding. The metabolism and pathway of the haptens as well as the activation and mechanism of action of the cells responsible for both the immune reaction and its completion are discussed in this article.