CLARICE TANAKA
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, Faculdade de Medicina - Docente
LIM/54 - Laboratório de Bacteriologia, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/54 - Laboratório de Bacteriologia, Hospital das Clínicas, Faculdade de Medicina - Líder
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
- Impact of Transcranial Direct Current Stimulation in Pain, Fatigue, and Health Quality of Life of Patients with Idiopathic Inflammatory Myopathies: A Randomized, Double-Blind, Sham-Controlled Crossover Clinical Trial(2024) MISSE, Rafael Giovani; SANTOS, Alexandre Moura dos; BORGES, Isabela Bruna Pires; GRECCO, Marcus Vinicius; FARIA, Marlise Sitima Mendes Simoes; SILVA, Lorenza Rosa Silverio da; CORREIA, Bruna Lindoso; KIM, Ana Woo Sook; TANAKA, Clarice; GREVE, Julia Maria D'Andrea; BAPTISTA, Abrahao Fontes; SHINJO, Samuel KatsuyukiObjectives. To assess the effectiveness of transcranial direct current stimulation (tDCS) for pain, fatigue, physical function, and health-related quality of life in patients with idiopathic inflammatory myopathy (IIM). Methods. This randomized, double-blind, sham-controlled, crossover clinical trial enrolled IIM patients with fatigue and pain who received tDCS (20 min, 2 mA) or sham stimulation for 10 daily sessions. Electrodes were placed according to the 10/20 EEG system. Both the groups underwent aerobic exercise training during the intervention period. The patients were evaluated for disease perception, pain, and fatigue using uni-multidimensional questionnaires and physical tests in the periods before and after the first and second interventions and after 12 weeks of follow-up. Results. After the tDCS intervention, a reduction in the general score of multidimensional pain of 32.0 (1.5-38.0) vs. 0.0 (0.0-13.4) with effect size (ES) of -0.78 was noted, and after sham intervention, a reduction of 26.0 (0.0-37.0) vs. 5.0 (0.0-19.2) with ES of -0.54 (P=0.047) was also noted. Similar results were evidenced with fatigue (22.5 (15.4-33.2) vs. 5.5 (0.0-14.6) with ES of -0.82) and sham intervention (21.0 (15.8-29.5) vs. 4.0 (4.0-17.5) with ES of -0.80 (P=0.012)). There were no differences in the domains of the fatigue and pain questionnaires. Adherence was observed in 88.8% of the patients without adverse events. Conclusion. The association of tDCS with aerobic training promoted additional effects in relation to the group subjected to placebo stimulation on general pain and fatigue scores, as well as on pain intensity, without changes in the subdomains of the pain and fatigue questionnaire. This trial is registered with NCT04678635.
- Transcranial direct current stimulation relieves the severe anxiety of a patient with COVID-19(2020) SHINJO, Samuel Katsuyuki; BRUNONI, Andre Russowsky; OKANO, Alexandre Hideki; TANAKA, Clarice; BAPTISTA, Abrahao Fontes
- Applications of Non-invasive Neuromodulation for the Management of Disorders Related to COVID-19(2020) BAPTISTA, Abrahao Fontes; BALTAR, Adriana; OKANO, Alexandre Hideki; MOREIRA, Alexandre; CAMPOS, Ana Carolina Pinheiro; FERNANDES, Ana Mercia; BRUNONI, Andre Russowsky; BADRAN, Bashar W.; TANAKA, Clarice; ANDRADE, Daniel Ciampi de; MACHADO, Daniel Gomes da Silva; MORYA, Edgard; TRUJILLO, Eduardo; SWAMI, Jaiti K.; CAMPRODON, Joan A.; MONTE-SILVA, Katia; SA, Katia Nunes; NUNES, Isadora; GOULARDINS, Juliana Barbosa; BIKSON, Marom; SUDBRACK-OLIVEIRA, Pedro; CARVALHO, Priscila de; DUARTE-MOREIRA, Rafael Jardim; PAGANO, Rosana Lima; SHINJO, Samuel Katsuyuki; ZANA, YossiBackground: Novel coronavirus disease (COVID-19) morbidity is not restricted to the respiratory system, but also affects the nervous system. Non-invasive neuromodulation may be useful in the treatment of the disorders associated with COVID-19. Objective: To describe the rationale and empirical basis of the use of non-invasive neuromodulation in the management of patients with COVID-10 and related disorders. Methods: We summarize COVID-19 pathophysiology with emphasis of direct neuroinvasiveness, neuroimmune response and inflammation, autonomic balance and neurological, musculoskeletal and neuropsychiatric sequela. This supports the development of a framework for advancing applications of non-invasive neuromodulation in the management COVID-19 and related disorders. Results: Non-invasive neuromodulation may manage disorders associated with COVID-19 through four pathways: (1) Direct infection mitigation through the stimulation of regions involved in the regulation of systemic anti-inflammatory responses and/or autonomic responses and prevention of neuroinflammation and recovery of respiration; (2) Amelioration of COVID-19 symptoms of musculoskeletal pain and systemic fatigue; (3) Augmenting cognitive and physical rehabilitation following critical illness; and (4) Treating outbreak-related mental distress including neurological and psychiatric disorders exacerbated by surrounding psychosocial stressors related to COVID-19. The selection of the appropriate techniques will depend on the identified target treatment pathway. Conclusion: COVID-19 infection results in a myriad of acute and chronic symptoms, both directly associated with respiratory distress (e.g., rehabilitation) or of yet-to-be-determined etiology (e.g., fatigue). Non-invasive neuromodulation is a toolbox of techniques that based on targeted pathways and empirical evidence (largely in non-COVID-19 patients) can be investigated in the management of patients with COVID-19.
- Noninvasive Neuromodulation Techniques in Difficult Tracheostomy Weaning of Patients With Spinal Cord Injury Report of Two Cases(2021) CARVALHO, Priscila De; GOULARDINS, Juliana Barbosa; SOUSA, Danilo Miyoji Nakamura de; BARBOSA, Cristiane Marcela da Silva; CAETANO, Thabata Cristina Candido; SANTOS, Lucas de Macedo dos; ITO, Clara Hikari; HIROTA, Adriana Sayuri; PEREIRA, Rita Pavione Rodrigues; BAPTISTA, Abrahao Fontes; TANAKA, ClariceHigh spinal cord injured patients (SCI) are susceptible to respiratory muscle impairments. Transcranial direct current stimulation (tDCS) and peripheral electrical stimulation (PES) may influence the diaphragm's central control, but until now they are not described as a therapeutic resource for difficult weaning. We present two case reports of SCI patients (P1 and P2) with long-term tracheostomy (>40 days) and hospital stay (>50 days). In association with respiratory exercise, P1 received a combined application of anodal tDCS over the supplementary motor area plus sensory PES in the thoracic-abdominal muscles, and P2 received isolated excitatory PES in the abdominal muscles, applied daily except on weekends. Maximum inspiratory/expiratory pressure, peak cough flow, diaphragm excursion, and thickening fraction were measured in the first and last days of the protocol. Both patients had improvements, with clinical impact such as cough effectiveness, decannulated after 15 applications of stimulation. Augmentation of neural respiratory drive and corticospinal excitability is suggested.
- Transcranial direct current stimulation and cough effectiveness in SCI patients: case report(2020) CARVALHO, Priscila de; HIROTA, Adriana Sayuri; SANT'ANNA, Guadalupe Nery; GOULARDINS, Juliana Barbosa; SANTOS, Lucas Macedo; CAETANO, Thabata; ITO, Clara Hikari; MOL, Caroline Gomes; RODRIGUES, Rita Pavione; BAPTISTA, Abrahao Fontes; TANAKA, Clarice
- Beyond the target area: an integrative view of tDCS-induced motor cortex modulation in patients and athletes(2019) MORYA, Edgard; MONTE-SILVA, Katia; BIKSON, Marom; ESMAEILPOUR, Zeinab; BIAZOLI JR., Claudinei Eduardo; FONSECA, Andre; BOCCI, Tommaso; FARZAN, Faranak; CHATTERJEE, Raaj; HAUSDORFF, Jeffrey M.; MACHADO, Daniel Gomes da Silva; BRUNONI, Andre Russowsky; MEZGER, Eva; MOSCALESKI, Luciane Aparecida; PEGADO, Rodrigo; SATO, Joao Ricardo; CAETANO, Marcelo Salvador; SA, Katia Nunes; TANAKA, Clarice; LI, Li Min; BAPTISTA, Abrahao Fontes; OKANO, Alexandre HidekiTranscranial Direct Current Stimulation (tDCS) is a non-invasive technique used to modulate neural tissue. Neuromodulation apparently improves cognitive functions in several neurologic diseases treatment and sports performance. In this study, we present a comprehensive, integrative review of tDCS for motor rehabilitation and motor learning in healthy individuals, athletes and multiple neurologic and neuropsychiatric conditions. We also report on neuromodulation mechanisms, main applications, current knowledge including areas such as language, embodied cognition, functional and social aspects, and future directions. We present the use and perspectives of new developments in tDCS technology, namely high-definition tDCS (HD-tDCS) which promises to overcome one of the main tDCS limitation (i.e., low focality) and its application for neurological disease, pain relief, and motor learning/rehabilitation. Finally, we provided information regarding the Transcutaneous Spinal Direct Current Stimulation (tsDCS) in clinical applications, Cerebellar tDCS (ctDCS) and its influence on motor learning, and TMS combined with electroencephalography (EEG) as a tool to evaluate tDCS effects on brain function.