LETICIA LESSA MANSUR
Projetos de Pesquisa
Unidades Organizacionais
LIM/34 - Laboratório de Ciências da Reabilitação, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- Prevalence of Cognitive Impairment Without Dementia and Dementia in Tremembe, Brazil(2016) CESAR, Karolina G.; BRUCKI, Sonia M. D.; TAKADA, Leonel T.; NASCIMENTO, Luiz F. C.; GOMES, Camila M. S.; ALMEIDA, Milena C. S.; OLIVEIRA, Maira O.; PORTO, Fabio H. G.; SENAHA, Mirna L. H.; BAHIA, Valeria S.; SILVA, Thais B. L.; IANOF, Jessica N.; SPINDOLA, Livia; SCHMIDT, Magali T.; JORGE, Mario S.; VALE, Patricia H. F.; CECCHINI, Mario A.; CASSIMIRO, Luciana; SOARES, Roger T.; GONCALVES, Marcia R.; MARTINS, Ana C. S.; DARE, Patricia; SMID, Jerusa; PORTO, Claudia S.; CARTHERY-GOULART, Maria T.; YASSUDA, Monica S.; MANSUR, Leticia L.; NITRINI, RicardoBackground:The prevalence of cognitive impairment is insufficiently determined in developing countries. The aim of this study was to ascertain the prevalence of cognitive impairment without dementia and dementia in community-dwelling elderly in Brazil.Methods:This was a single-phase cross-sectional survey of the elderly (aged 60 years and above) living in the municipality of Tremembe, Brazil. Twenty percent of the households with elderly persons were randomly selected from urban and rural areas, to obtain a homogenous representation of all socioeconomic and cultural levels.Results:We assessed 630 individuals [mean age, 71.3 y (7.99); mean years of education, 4.9 (+/- 4.54)] and found prevalence rates of 17.5% (95% confidence interval, 14.6-20.6) for dementia and 19.5% (95% confidence interval, 16.6-22.8) for cognitive impairment without dementia. These prevalence rates were influenced by age (P<0.001) and by educational level (P<0.001). There was no significant sex difference among diagnostic groups (P=0.166). The prevalence of dementia was higher in relatively younger individuals (below 70 y) when compared with other studies. Besides, dementia was associated with low socioeconomic status, stroke, previous psychiatric disorder, alcoholism, and epilepsy.Conclusions:The prevalence of dementia in this study was higher than in other studies, particularly among younger elderly.
- Performance of the Visual Analogue Scale of Happiness and of the Cornell Scale for Depression in Dementia in the Tremembé Epidemiological Study, Brazil(2014) CÉSAR, Karolina G.; BRUCKI, Sonia M.D.; TAKADA, Leonel T.; NASCIMENTO, Luiz Fernando C.; GOMES, Camila M.S.; ALMEIDA, Milena C.S.; OLIVEIRA, Maira O.; PORTO, Fábio H.G.; SENAHA, Mirna L.H.; BAHIA, Valéria S.; SILVA, Thaís Bento L.; IANOF, Jéssica N.; SPÍNDOLA, Lívia; SCHMIDT, Magali T.; JORGE, Mário S.; VALE, Patrícia H.F.; CECCHINI, Mário A.; CASSIMIRO, Luciana; SOARES, Roger T.; GONÇALVES, Márcia R.; SMID, Jerusa; PORTO, Claudia S.; CARTHERY-GOULART, Maria Teresa; YASSUDA, Mônica S.; MANSUR, Letícia L.; NITRINI, RicardoDepression is a major growing public health problem. Many population studies have found a significant relationship between depression and the presence of cognitive disorders. OBJECTIVE: To establish the correlation between the Visual Analogue Scale of Happiness and the Cornell Scale for Depression in Dementia in the population aged 60 years or over in the city of Tremembé, state of São Paulo, Brazil. METHODS: An epidemiological survey involving home visits was carried out in the city of Tremembé. The sample was randomly selected by drawing 20% of the population aged 60 years or older from each of the city's census sectors. In this single-phase study, the assessment included clinical history, physical and neurological examination, cognitive evaluation, and application of both the Cornell Scale and the Analogue Scale of Happiness for psychiatric symptoms. The presence of depressive symptoms was defined as scores greater than or equal to 8 points on the Cornell Scale. RESULTS: A total of 623 subjects were evaluated and of these 251 (40.3%) had clinically significant depressive symptoms on the Cornell Scale, with a significant association with female gender (p<0.001) and with lower education (p=0.012). One hundred and thirty-six participants (21.8%) chose the unhappiness faces, with a significant association with age (p<0.001), female gender (p=0.020) and low socioeconomic status (p=0.012). Although there was a statistically significant association on the correlation test, the correlation was not high (rho=0.47). CONCLUSION: The prevalence of depressive symptoms was high in this sample and the Visual Analogue Scale of Happiness and Cornell Scale for Depression in Dementia should not be used as similar alternatives for evaluating the presence of depressive symptoms, at least in populations with low educational level.
- Prevalence of cognitive impairment in tremembe, Brazil(2015) CESAR, K. G.; BRUCKI, S. M. D.; TAKADA, L. T.; OLIVEIRA, M. O.; PORTO, F. H. G.; SENAHA, M. L. H.; BAHIA, V. S.; SILVA, T. B. L.; CECCHINI, M. A.; CASSIMIRO, L.; SMID, J.; PORTO, C. S.; CARTHERY-GOULART, M. T.; YASSUDA, M. S.; MANSUR, L. L.; NITRINI, R.
- Dementia in Latin America: Paving the way toward a regional action plan(2021) PARRA, Mario Alfredo; BAEZ, Sandra; SEDENO, Lucas; CAMPO, Cecilia Gonzalez; SANTAMARIA-GARCIA, Hernando; APRAHAMIAN, Ivan; BERTOLUCCI, Paulo H. F.; BUSTIN, Julian; BICALHO, Maria Aparecida Camargos; CANO-GUTIERREZ, Carlos; CARAMELLI, Paulo; CHAVES, Marcia L. F.; COGRAM, Patricia; BEBER, Barbara Costa; COURT, Felipe A.; SOUZA, Leonardo Cruz de; CUSTODIO, Nilton; DAMIAN, Andres; CRUZ, Myriam de la; RODRIGUEZ, Roberta Diehl; BRUCKI, Sonia Maria Dozzi; FAJERSZTAJN, Lais; FARIAS, Gonzalo A.; FELICE, Fernanda G. De; FERRARI, Raffaele; OLIVEIRA, Fabricio Ferreira de; FERREIRA, Sergio T.; FERRETTI, Ceres; BALTHAZAR, Marcio Luiz Figueredo; FROTA, Norberto Anizio Ferreira; FUENTES, Patricio; GARCIA, Adolfo M.; GARCIA, Patricia J.; PORTO, Fabio Henrique de Gobbi; PENAILILLO, Lissette Duque; ENGLER, Henry Willy; MAIER, Irene; MATA, Ignacio F.; GONZALEZ-BILLAULT, Christian; LOPEZ, Oscar L.; MORELLI, Laura; NITRINI, Ricardo; QUIROZ, Yakeel T.; BARRAGAN, Alejandra Guerrero; HUEPE, David; PIO, Fabricio Joao; SUEMOTO, Claudia Kimie; KOCHHANN, Renata; KOCHEN, Silvia; KUMFOR, Fiona; LANATA, Serggio; MILLER, Bruce; MANSUR, Leticia Lessa; HOSOGI, Mirna Lie; LILLO, Patricia; GUERRA, Jorge Llibre; LIRA, David; LOPERA, Francisco; COMAS, Adelina; AVILA-FUNES, Jose Alberto; SOSA, Ana Luisa; RAMOS, Claudia; RESENDE, Elisa de Paula Franca; SNYDER, Heather M.; TARNANAS, Ioannis; YOKOYAMA, Jenifer; LLIBRE, Juan; CARDONA, Juan Felipe; POSSIN, Kate; KOSIK, Kenneth S.; MONTESINOS, Rosa; MOGUILNER, Sebastian; SOLIS, Patricia Cristina Lourdes; FERRETTI-REBUSTINI, Renata Eloah de Lucena; RAMIREZ, Jeronimo Martin; MATALLANA, Diana; MBAKILE-MAHLANZA, Lingani; TON, Alyne Mendonca Marques; TAVARES, Ronnielly Melo; MIOTTO, Eliane C.; MUNIZ-TERRERA, Graciela; MUNOZ-NEVAREZ, Luis Arnoldo; OROZCO, David; OLIVEIRA, Maira Okada de; PIGUET, Olivier; CAIPA, Maritza Pintado; ESCUDERO, Stefanie Danielle Pina; SCHILLING, Lucas Porcello; PALMEIRA, Andre Luiz Rodrigues; YASSUDA, Monica Sanches; SANTACRUZ-ESCUDERO, Jose Manuel; SERAFIM, Rodrigo Bernardo; SMID, Jerusa; SLACHEVSKY, Andrea; SERRANO, Cecilia; SOTO-ANARI, Marcio; TAKADA, Leonel Tadao; GRINBERG, Lea Tenenholz; TEIXEIRA, Antonio Lucio; BARBOSA, Maira Tonidandel; TREPEL, Dominic; IBANEZ, AgustinAcross Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC-CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence-based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.
- Primary progressive aphasia: Classification of variants in 100 consecutive Brazilian cases(2013) SENAHA, Mirna Lie Hosogi; CARAMELLI, Paulo; BRUCKI, Sonia M.D.; SMID, Jerusa; TAKADA, Leonel T.; PORTO, Claudia S.; CÉSAR, Karolina G.; MATIOLI, Maria Niures P.; SOARES, Roger T.; MANSUR, Letícia L.; NITRINI, RicardoABSTRACT Primary progressive aphasia (PPA) is a neurodegenerative clinical syndrome characterized primarily by progressive language impairment. Recently, consensus diagnostic criteria were published for the diagnosis and classification of variants of PPA. The currently recognized variants are nonfluent/agrammatic (PPA-G), logopenic (PPA-L) and semantic (PPA-S). Objective: To analyze the demographic data and the clinical classification of 100 PPA cases. Methods: Data from 100 PPA patients who were consecutively evaluated between 1999 and 2012 were analyzed. The patients underwent neurological, cognitive and language evaluation. The cases were classified according to the proposed variants, using predominantly the guidelines proposed in the consensus diagnostic criteria from 2011. Results: The sample consisted of 57 women and 43 men, aged at onset 67.2±8.1 years (range of between 53 and 83 years). Thirty-five patients presented PPA-S, 29 PPA-G and 16 PPA-L. It was not possible to classify 20% of the cases into any one of the proposed variants. Conclusion: It was possible to classify 80% of the sample into one of the three PPA variants proposed. Perhaps the consensus classification requires some adjustments to accommodate cases that do not fit into any of the variants and to avoid overlap where cases fit more than one variant. Nonetheless, the established current guidelines are a useful tool to address the classification and diagnosis of PPA and are also of great value in standardizing terminologies to improve consistency across studies from different research centers.