DECIO MION JUNIOR
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- Guidelines on the management of arterial hypertension and related comorbidities in Latin America(2017) BARBOS, Eduardo; COCA, Antonio; LOPEZ-JARAMILLO, Patricio; RAMIREZ, Agustin J.; SANCHEZ, Ramiro A.; ZANCHETTI, Alberto; BURLANDO, Guillermo; GONZALEZ, Claudio; PISKORZ, Daniel; RAMIREZ, Agustin J.; SANCHEZ, Ramiro A.; SIMSOLO, Rosa; VOTO, Liliana; WAISSMAN, Gabriel Dario; ALESSI, Alexandre; AMODEO, Celso; BRANDAO, Andrea Araujo; BAIOCCHI, Sergio; BARBOSA, Eduardo; BARRETO FILHO, Jose Augusto; BORTOLOTTO, Luiz Aparecido; JARDIM, Paulo Cesar Brandao Veiga; BRASIL, David; MIRANDA, Roberto Dischinger; FRITSCH, Mario; KALIL, Marcio; MACHADO, Carlos Alberto; FEITOSA, Audes Magalhaes; MALACHIAS, Marcus Vinicius Bolivar; MALTA, Deborah; MION JR., Decio; MOREIRA FILHO, Osni; MORENO, Heitor; GOMES, Marco Mota; NOBRE, Fernando; NOGUEIRA, Armando; OIGMAN, Wille; PASSARELLI JR., Oswaldo; RIBEIRO, Jose Marcio; POVOA, Rui Manoel Santos; SCHMID, Helena; BARROSO, Weimar Kunz Sebba; JARDIM, Thiago Veiga; VILELA-MARTIN, Jose Fernando; COBOS, Leonardo; LANAS, Fernando; MOYA, Raul Villar; MENDOZA, Jose Luis Accini; GARCIA-ORTIZ, Luis Hernando; LOPEZ-JARAMILLO, Patricio; MOLINA, Dora Ines; SANCHEZ, Gregorio; URINA-TRIANA, Miguel; MORALES-SALINAS, Alberto; LARA, Joffre; WYSS, Fernando Stuardo; ALCOCER, Luis; CAAMANO, Angel Gonzalez; PARRA-CARRILLO, Jose Z.; ORTELLADO, Jose; MONCLOA, Alfonso Bryce; SANTISTEBAN, Segundo Senclen; DIAZ, Margarita E.; HERNANDEZ, Rafael Hernandez; LOPEZ, Jesus; MACHADO, Livia T.; PONTE-NEGRETTI, Carlos
- Can blood pressure decrease after maximal exercise test predict the blood pressure lowering effect of aerobic training in treated hypertensive men?(2023) AZEVEDO, Luan Morais; BRITO, Leandro Campos de; PECANHA, Tiago; FECCHIO, Rafael Yokoyama; REZENDE, Rafael Andrade; SILVA, Giovanio Vieira da; PIO-ABREU, Andrea; MION JUNIOR, Decio; HALLIWILL, John Robert; FORJAZ, Claudia Lucia de MoraesThe acute decrease in blood pressure (BP) observed after a session of exercise (called post-exercise hypotension) has been proposed as a tool to predict the chronic reduction in BP induced by aerobic training. Therefore, this study investigated whether post-exercise hypotension observed after a maximal exercise test is associated to the BP-lowering effect of aerobic training in treated hypertensives. Thirty hypertensive men (50 & PLUSMN; 8 years) who were under consistent anti-hypertensive treatment underwent a maximal exercise test (15 watts/min until exhaustion), and post-exercise hypotension was determined by the difference between BP measured before and at 30 min after the test. Subsequently, the patients underwent 10 weeks of aerobic training (3 times/week, 45 min/session at moderate intensity), and the BP-lowering effect of training was assessed by the difference in BP measured before and after the training period. Pearson correlations were employed to evaluate the associations. Post-maximal exercise test hypotension was observed for systolic and mean BPs (-8 & PLUSMN; 6 and -2 & PLUSMN; 4 mmHg, all P < 0.05). Aerobic training reduced clinic systolic/diastolic BPs (-5 & PLUSMN; 6/-2 & PLUSMN; 3 mmHg, both P < 0.05) as well as awake and 24 h mean BPs (-2 & PLUSMN; 6 and -2 & PLUSMN; 5 mmHg, all P < 0.05). No significant correlation was detected between post-exercise hypotension and the BP-lowering effect of training either for clinic or ambulatory BPs (r values ranging from 0.00 to 0.32, all p > 0.05). Post-exercise hypotension assessed 30 min after a maximal exercise test cannot be used to predict the BP-lowering effect of aerobic training in treated hypertensive men.
- Morning versus Evening Aerobic Training Effects on Blood Pressure in Treated Hypertension(2019) BRITO, Leandro C.; PECANHA, Tiago; FECCHIO, Rafael Y.; REZENDE, Rafael A.; SOUSA, Patricia; SILVA-JUNIOR, Natan Da; ABREU, Andrea; SILVA, Giovanio; MION-JUNIOR, Decio; HALLIWILL, John R.; FORJAZ, Claudia L. M.Introduction: The acute blood pressure (BP) decrease is greater after evening than morning exercise, suggesting that evening training (ET) may have a greater hypotensive effect. Objective: This study aimed to compare the hypotensive effect of aerobic training performed in the morning versus evening in treated hypertensives. Methods: Fifty treated hypertensive men were randomly allocated to three groups: morning training (MT), ET, and control (C). Training groups cycled for 45 min at moderate intensity (progressing from the heart rate of the anaerobic threshold to 10% below the heart rate of the respiratory compensation point), while C stretched for 30 min. Interventions were conducted 3 times per week for 10 wk. Clinic and ambulatory BP and hemodynamic and autonomic mechanisms were evaluated before and after the interventions. Clinic assessments were performed in the morning (7: 00-9: 00 AM) and evening (6: 00-8: 00 PM). Between-within ANOVA was used (P <= 0.05). Results: Only ET decreased clinic systolic BP differently from C and MT (morning assessment -5 +/- 6 mm Hg and evening assessment -8 +/- 7 mmHg, P G 0.05). Only ET reduced 24 h and asleep diastolic BP differently from C and MT (-3 +/- 5 and -3 +/- 4 mm Hg, respectively, P G 0.05). Systemic vascular resistance decreased from C only in ET (P = 0.03). Vasomotor sympathetic modulation decreased (P = 0.001) and baroreflex sensitivity (P G 0.02) increased from C in both training groups with greater changes in ET than MT. Conclusions: In treated hypertensive men, aerobic training performed in the evening decreased clinic and ambulatory BP due to reductions in systemic vascular resistance and vasomotor sympathetic modulation. Aerobic training conducted at both times of day increases baroreflex sensitivity, but with greater after ET.
- Effects of ACEi and ARB on post-exercise hypotension induced by exercises conducted at different times of day in hypertensive men(2020) BRITO, Leandro C.; AZEVEDO, Luan; PECANHA, Tiago; FECCHIO, Rafael Yokoyama; REZENDE, Rafael Andrade; SILVA, Giovanio Vieira da; PIO-ABREU, Andrea; MION, Decio; HALLIWILL, John R.; FORJAZ, Claudia L. M.Background Post-exercise hypotension (PEH) is greater after evening than morning exercise, but antihypertensive drugs may affect the evening potentiation of PEH. Objective: To compare morning and evening PEH in hypertensives receiving angiotensin-converting enzyme inhibitors (ACEi) or angiotensin II receptor blockers (ARB). Methods Hypertensive men receiving ACEi (n = 14) or ARB (n = 15) underwent, in a random order, two maximal exercise tests (cycle ergometer, 15 watts/min until exhaustion) with one conducted in the morning (7 and 9 a.m.) and the other in the evening (8 and 10 p.m.). Auscultatory blood pressure (BP) was assessed in triplicate before and 30 min after the exercises. Changes in BP (post-exercise - pre-exercise) were compared between the groups and the sessions using a two-way mixed ANOVA and consideringPResults In the ARB group, systolic BP decrease was greater after the evening than the morning exercise, while in the ACEi group, it was not different after the exercises conducted at the different times of the day. Additionally, after the evening exercise, systolic BP decrease was lower in the ACEi than the ARB group (ARB = -11 +/- 8 vs -6 +/- 6 and ACEi = -6 +/- 7 vs. -8 +/- 5 mmHg, evening vs. morning, respectively, P for interaction = 0.014). Conclusions ACEi, but not ARB use, blunts the greater PEH that occurs after exercise conducted in the evening than in the morning.