EDSON ABDALA
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Moléstias Infecciosas e Parasitárias, Faculdade de Medicina - Docente
LIM/37 - Laboratório de Transplante e Cirurgia de Fígado, Hospital das Clínicas, Faculdade de Medicina
LIM/47 - Laboratório de Hepatologia por Vírus, Hospital das Clínicas, Faculdade de Medicina
LIM/37 - Laboratório de Transplante e Cirurgia de Fígado, Hospital das Clínicas, Faculdade de Medicina
LIM/47 - Laboratório de Hepatologia por Vírus, Hospital das Clínicas, Faculdade de Medicina
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Resultados de Busca
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conferenceObject The Influence of Antifungal Prophylaxis in Invasive Fungal Infections in Liver Transplantation(2015) SONG, Alice T. W.; ALMEIDA JUNIOR, Joao N.; MAU, Luciana B.; FREIRE, Maristela; PROENCA, Adriana; HADDAD, Luciana; D'ALBUQUERQUE, Luiz A. C.; ABDALA, Edson- Carbapenem-Resistant Enterobacteriaceae Acquired Before Liver Transplantation: Impact on Recipient Outcomes(2017) FREIRE, Maristela Pinheiro; OSHIRO, Isabel C. V. S.; PIERROTTI, Ligia C.; BONAZZI, Patricia R.; OLIVEIRA, Larissa M. de; SONG, Alice T. W.; CAMARGO, Carlos H.; HEIJDEN, Inneke M. van der; ROSSI, Flavia; COSTA, Silvia F.; D'ALBUQUERQUE, Luiz A. C.; ABDALA, EdsonBackground. Carbapenem-resistant Enterobacteriaceae (CRE) is an emergent microorganism of infections after liver transplant (LT). The aim of this study was to analyze the risk factors for CRE acquisition and infection after LT. Methods. This was a prospective cohort study involving patients who underwent LT in the 2010 to 2014 period. Surveillance cultures for CRE were collected immediately before LT and weekly thereafter until hospital discharge. Results. We analyzed 386 patients undergoing a total of 407 LTs. Before LT, 68 (17.6%) patients tested positive for CRE, 11 (16.2%) of those patients having CRE infection, whereas 119 (30.8%) patients acquired CRE after LT. Post-LT CRE infection was identified in 59 (15.7%) patients: Klebsiella pneumoniae was isolated in 83.2%; surgical site infection was the most common type of infection (46.7%). Multivariate analysis showed that post-LT dialysis was the only risk factor for post-LT CRE acquisition. Eighty-two percent of patients who underwent 3 or more post-LT dialysis sessions and acquired CRE before LT evolved with post-LT CRE infection. Other risk factors for CRE infection were acquisition of CRE post-LT, Model for End-Stage Liver Disease score greater than 32, combined transplantation, and reoperation. Patients who acquired CRE before LT had a high risk of developing CRE infection (P < 0.001). Conclusions. Measures for minimizing that risk, including altering the antibiotic prophylaxis, should be investigated and implemented.
- Endemic Fungal Infection Recommendations for Solid-Organ Transplant Recipients and Donors(2018) ABDALA, Edson; MILLER, Rachel; PASQUALOTTO, Alessandro Comaru; MUNOZ, Patricia; COLOMBO, Arnaldo Lopes; CUENCA-ESTRELLA, Manuel
- Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America(2018) CLEMENTE, Wanessa Trindade; PIERROTTI, Ligia Camera; ABDALA, Edson; MORRIS, Michele I.; AZEVEDO, Luiz S.; LOPEZ-VELEZ, Rogelio; CUENCA-ESTRELLA, Manuel; TORRE-CISNEROS, Julian; PETERSEN, Eskild; CAMARGO, Luis Fernando A.; WRIGHT, Alissa Jade; BEECHING, Nicholas J.; VILELA, Eduardo Garcia; SANTORO-LOPES, Guilherme; LEN, Oscar; STUCCHI, Raquel S. B.; MANUEL, Oriol; FARIA, Luciana Costa; LEBLEBICIOGLU, Hakan; HUPRIKAR, Shirish; MOLINA, Israel; MOURAO, Paulo Henrique Orlandi; KOTTON, Camille N.; AGUADO, Jose MariaThe Recommendations for Management of Endemic Diseases and Travel Medicine in Solid-Organ Transplant Recipients and Donors: Latin America clinical practice guideline is intended to guide clinicians caring for solid-organ transplant (SOT) donors, candidates and recipients regarding infectious diseases (ID) issues related to this geographical region, mostly located in the tropics. These recommendations are based on both systematic reviews of relevant literature and expert opinion from both transplant ID and travel medicine specialists. The guidelines provide recommendations for risk evaluation and laboratory investigation, as well as management and prevention of infection of the most relevant endemic diseases of Latin America. This summary includes a brief description of the guideline recommendations but does not include the complete rationale and references for each recommendation, which is available in the online version of the article, published in this journal as a supplement. The supplement contains 10 reviews referring to endemic or travel diseases (eg, tuberculosis, Chagas disease [ChD], leishmaniasis, malaria, strongyloidiasis and schistosomiasis, travelers diarrhea, arboviruses, endemic fungal infections, viral hepatitis, and vaccines) and an illustrative section with maps (http://www.pmourao.com/map/). Contributors included experts from 13 countries (Brazil, Canada, Chile, Denmark, France, Italy, Peru, Spain, Switzerland, Turkey, United Kingdom, United States, and Uruguay) representing four continents (Asia, the Americas and Europe), along with scientific and medical societies.
conferenceObject Liver transplant recipients infected with Sars-CoV-2 in the early versus late postoperative period: is there a difference in outcomes?(2021) LIMA, M. R. Damasceno; WAISBERG, D.; TERRABUIO, D. R. Benedita; SONG, A.; ABDALA, E.; DUCATTI, L.; HADDAD, L. Bertocco; GOUVEIA, L. Nunes; ROCHA-SANTOS, V.; MARTINO, R. Bronze; NACIF, L. Souto; PINHEIRO, R. Soares; ARANTES, R. Macedo; ERNANI, L.; GALVAO, F. H.; LEE, Dong Won A.; MALBOUISSON, L. M.; ROCHA FILHO, J. Avancini; ANDRAUS, W.; CARNEIRO-D'ALBUQUERQUE, L. A.