RODRIGO OLIVA PEREZ
Índice h a partir de 2011
25
Projetos de Pesquisa
Unidades Organizacionais
3 resultados
Resultados de Busca
Agora exibindo 1 - 3 de 3
- Session 4: Trying to augment response with chemotherapy: a triumph of hope over experience?(2018) BATTERSBY, N. J.; PEREZ, R. O.; BAXTER, N.; MORAN, B.; BROWN, G.As part of an approach to improve tumour regression and increase the proportion of patients with complete clinical and radiological response, Dr Perez reviews the methods and evidence base for augmenting therapy and thus augmenting response rates preoperatively. Much of the data reviewed were in the context of patients undergoing a watch-and-wait approach for rectal cancer after initial treatment with chemoradiotherapy.
- Strategies to improve clinical research in surgery through international collaboration(2013) SOREIDE, Kjetil; ALDERSON, Derek; BERGENFELZ, Anders; BEYNON, John; CONNOR, Saxon; DECKELBAUM, Dan L.; DEJONG, Cornelis H.; EARNSHAW, Jonathan J.; KYAMANYWA, Patrick; PEREZ, Rodrigo O.; SAKAI, Yoshiharu; WINTER, Desmond C.More than 235 million patients undergo surgery every year worldwide, but less than 1% are enrolled in surgical clinical trials-few of which are international collaborations. Several levels of action are needed to improve this situation. International research collaborations in surgery between developed and developing countries could encourage capacity building and quality improvement, and mutually enhance care for patients with surgical disorders. Low-income and middle-income countries increasingly report much the same range of surgical diseases as do high-income countries (eg, cancer, cardiovascular disease, and the surgical sequelae of metabolic syndrome); collaboration is therefore of mutual interest. Large multinational trials that cross cultures and levels of socioeconomic development might have faster results and wider applicability than do single-country trials. Surgeons educated in research methods, and aided by research networks and trial centres, are needed to foster these international collaborations. Barriers to collaboration could be overcome by adoption of global strategies for regulation, health insurance, ethical approval, and indemnity coverage for doctors.
- The Future of Rectal Cancer Surgery: A Narrative Review of an International Symposium(2018) LACY, F. Borja de; CHADI, Sami A.; BERHO, Mariana; HEALD, Richard J.; KHAN, Jim; MORAN, Brendan; PANIS, Yves; PEREZ, Rodrigo; TEKKIS, Paris; MORTENSEN, Neil J.; LACY, Antonio M.; WEXNER, Steven D.; CHAND, ManishSurgery remains the mainstay of curative treatment for primary rectal cancer. For mid and low rectal tumors, optimal oncologic surgery requires total mesorectal excision (TME) to ensure the tumor and locoregional lymph nodes are removed. Adequacy of surgery is directly linked to survival outcomes and, in particular, local recurrence. From a technical perspective, the more distal the tumor, the more challenging the surgery and consequently, the risk for oncologically incomplete surgery is higher. TME can be performed by an open, laparoscopic, robotic or transanal approach. There is a lack of consensus on the gold standard approach with each of these options offering specific advantages. The International Symposium on the Future of Rectal Cancer Surgery was convened to discuss the current challenges and future pathways of the 4 approaches for TME. This article reviews the findings and discussion from an expert, international panel.