NANA MIURA IKARI
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
2 resultados
Resultados de Busca
Agora exibindo 1 - 2 de 2
article 5 Citação(ões) na Scopus Tratamento cirúrgico da persistência do canal arterial na população adulta(2011) JATENE, Marcelo Biscegli; ABUCHAIM, Decio Cavalet Soares; TIVERON, Marcos G.; TANAMATI, Carla; MIURA, Nana; RISO, Arlindo; AUIK, Edrnar; LOPES, Antonio Augusto; MARCIAL, Miguel BarberoObjective: To analyze 34 patients submitted to surgical treatment of patent arterial duct with age beyond 18 years old. Methods: Retrospective data collected from patient's charts with more than eighteen years old, submitted to surgical correction of patent arterial duct between 1997 and 2008 at Instituto do Coracao da Faculdade de Medicina da Universidade de Sao Paulo. Results: The mean age was 28.7 (18 a 53) years and 22 (64.7%) were female. The more prevalent symptom was dyspnea (76.5%). Left lateral thoracotomy was used in 33 (97.1%); the DA was sectioned and sutured in 25 (73.5%) cases and one patient needed cardiopulmonary bypass support. There were eight (23.5%) calcified arterial duct and 12 (35.3%) previous treatment with transcatheter devices were performed. The complication rate was 32%, with one (2.9%) permanent vocal cord palsy. Two (5.8%) patients had residual shunt less than 2mm. Transient left cord voice palsy was observed in 3 (8.8%) The procedure improves functional class (P < 0.0001) and no mortality was observed. Conclusion: In this series, the surgical treatment of patent arterial duct in adults could be done without mortality and low incidence of complications.- Holt-Oram syndrome: novel TBX5 mutation and associated anomalous right coronary artery(2011) VIANNA, Caio B.; MIURA, Nana; PEREIRA, Alexandre C.; JATENE, Marcelo B.The Holt-Oram syndrome was confirmed in an asymptomatic 36-year-old man by a novel TBX5-gene mutation (exon 8 acceptor splicing site, c.663-1G greater than A). Computed tomography showed an atrial septal defect and an anomalous right coronary artery crossing between the aorta and pulmonary arteries. Surgery corrected the septal defect and the initial segment of the anomalous vessel was unroofed and enlarged. Anomalous coronary arteries were not previously described in the Holt-Oram syndrome patients and should be added to the list of possible associated cardiac defects.