RICHARD LOUIS VOEGELS

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Departamento de Otorrinolaringologia e Oftalmologia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/32 - Laboratório de Otorrinolaringologia, Hospital das Clínicas, Faculdade de Medicina - Líder

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  • article 1776 Citação(ões) na Scopus
    European Position Paper on Rhinosinusitis and Nasal Polyps 2020
    (2020) FOKKENS, Wytske J.; LUND, Valerie J.; HOPKINS, Claire; HELLINGS, Peter W.; KERN, Robert; REITSMA, Sietze; TOPPILA-SALMI, Sanna; BERNAL-SPREKELSEN, Manuel; MULLOL, Joaquim; ALOBID, Isam; ANSELMO-LIMA, Wilma Terezinha; BEDOYA, Juan David; BEULE, Achim; BOFARES, Khaled M.; BRAVERMAN, Itzhak; BROZEK-MADRY, Eliza; BYARUHANGA, Richard; CALLEJAS, Claudio; CARRIE, Sean; HAMIZAN, Aneeza W.; MAHDJOUBI, Abdelhak; OZKAN, Muge; CAULLEY, Lisa; CHUSSI, Desderius; CORSO, Eugenio de; COSTE, Andre; HADI, Usama El; ELFAROUK, Ahmed; ELOY, Philippe H.; FARROKHI, Shokrollah; FELISATI, Giovanni; HEINICHEN, Julio V.; PERIC, Aleksandar; FERRARI, Michel D.; MESBAHI, Alireza; FISHCHUK, Roman; GRAYSON, Jessica W.; HUSAIN, Salina; PING, Tang Ing; IVASKA, Justinas; NETKOVSKI, Jane; JAKIMOVSKA, Frodita; KOSAK, Tanja Soklic; PLZAK, Jan; JOVANCEVIC, Ljiljana; KAKANDE, Emily; KAMEL, Reda; KARPISCHENKO, Sergei; KARIYAWASAM, Harsha H.; KAWAUCHI, Hideyuki; KJELDSEN, Anette; KLIMEK, Ludger; KRZESKI, Antoni; TSHIPUKANE, Dieudonne Nyenbue; PROKOPAKIS, Emmanuel; STJARNE, Par; BARSOVA, Gabriela Kopacheva; KIM, Sung Wam; LAL, Devyani; LETORT, Jose J.; OBANDO-VALVERDE, Andres; OKANO, Mitsuhiro; ONERCI, Metin; ONG, Yew Kwang; ORLANDI, Richard; PREPAGERAN, Nerayanan; BACHERT, Claus; SUTIKNO, Budi; OTORI, Nobuyoshi; OUENNOUGHY, Kheir; PSALTIS, Alkis; PUGIN, Benoit; RAFTOPULOS, Marco; STEINSVAG, Sverre; BAROODY, Fuad; JOOS, Guy F.; ROMBAUX, Philippe; RIECHELMANN, Herbert; SAHTOUT, Semia; SARAFOLEANU, Caius-Codrut; SEARYOH, Kafui; RHEE, Chae-Seo; SHI, Jianbo; SHKOUKANI, Mahdi; SHUKURYAN, Arthur K.; TANTILIPIKORN, Pongsakorn; KALOGJERA, Livije; SICAK, Marian; BUCHWALD, Christian von; SMYTH, David; SNIDVONGS, Kornkiat; THANAVIRATANANICH, Sanguansak; Thuy Tran; URBANCIC, Jure; CERVIN, Anders; VALIULIS, Arunas; AHLSTROM-EMANUELSSON, Cecilia; KNILL, Andrew; APARICIO, Carolina Vasquez de; VICHEVA, Dilyana; VIRKKULA, Paula M.; VICENTE, Gil; VOEGELS, Richard; WAGENMANN, Martin; WARDANI, Retno S.; WELGE-LUSSEN, Antje; WITTERICK, Ian; COHEN, Noam; KOCKS, Janwillem H.; ALABRI, Rashid; WRIGHT, Erin; ZABOLOTNIY, Dmytro; ZSOLT, Bella; ZWETSLOOT, Casper P.; CONSTANTINIDIS, Jannis; GABORY, Ludovic De; DESROSIERS, Martin; DIAMANT, Zuzana; DOUGLAS, Richard G.; LANDIS, Basile N.; GEVAERT, Philippe H.; ALBU, Silviu; HAFNER, Anita; HARVEY, Richard J.; LIMPENS, Jacqueline; LEBEER, Sarah; LOURENCO, Olga; ALHABASH, Saied; MATRICARDI, Paolo M.; GONCALVES, Paulo M.; MECO, Cem; O'MAHONY, Liam; PHILPOTT, Carl M.; RYAN, Dermot; SCHLOSSER, Rodney; SENIOR, Brent; SMITH, Timothy L.; TEELING, Thijs; TOMAZIC, Peter Valentin; ALEKSIC, Aleksandra; GRDINIC, Boris; WANG, De Yun; WANG, Dehui; ZHANG, Luo; AGIUS, Adrian M.; ALOULAH, Mohammad; AL-QUDAH, Mohannad; ALSALEH, Saad; BABAN, Muaid Aziz; BAUDOIN, Tomislav; LOPATIN, Andrey; GRGIC, Velimir; BALVERS, Tijmen; BATTAGLIA, Paolo
    The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undertaken in the eight years since the EPOS2012 position paper was published and addresses areas not extensively covered in EPOS2012 such as paediatric CRS and sinus surgery. EPOS2020 also involves new stakeholders, including pharmacists and patients, and addresses new target users who have become more involved in the management and treatment of rhinosinusitis since the publication of the last EPOS document, including pharmacists, nurses, specialised care givers and indeed patients themselves, who employ increasing self-management of their condition using over the counter treatments. The document provides suggestions for future research in this area and offers updated guidance for definitions and outcome measurements in research in different settings. EPOS2020 contains chapters on definitions and classification where we have defined a large number of terms and indicated preferred terms. A new classification of CRS into primary and secondary CRS and further division into localized and diffuse disease, based on anatomic distribution is proposed. There are extensive chapters on epidemiology and predisposing factors, inflammatory mechanisms, (differential) diagnosis of facial pain, allergic rhinitis, genetics, cystic fibrosis, aspirin exacerbated respiratory disease, immunodeficiencies, allergic fungal rhinosinusitis and the relationship between upper and lower airways. The chapters on paediatric acute and chronic rhinosinusitis are totally rewritten. All available evidence for the management of acute rhinosinusitis and chronic rhinosinusitis with or without nasal polyps in adults and children is systematically reviewed and integrated care pathways based on the evidence are proposed. Despite considerable increases in the amount of quality publications in recent years, a large number of practical clinical questions remain. It was agreed that the best way to address these was to conduct a Delphi exercise. The results have been integrated into the respective sections. Last but not least, advice for patients and pharmacists and a new list of research needs are included.
  • article
    Endoscopic Study of Ethmoidal Canals in Cadavers, Including a Histological Analysis of Their Contents
    (2024) FELIPPU, Alexandre Wady Debes; MORSCH, Thiago Picolli; FELIPPU, Andre Wady Debes; CASCIO, Filippo; OLIVEIRA, Claudia Regina Gomes Cardim Mendes de; FELIPPU, Alexandre; VOEGELS, Richard Louis
    Introduction The advent of the endoscope has enabled the use of the endonasal approach for a variety of diseases. Studying the ethmoidal canals is important for surgeries of the paranasal sinuses and the anterior base of the skull.Objective To investigate the ethmoidal canals and evaluate their structure, the presence of vessels and nerves, their location, and to perform an anatomopathological study of their contents.Methods We evaluated 20 cadavers (20 left and 20 right nasal cavities) through endoscopic dissection of the anterior base of the skull and exposure of the medial periorbita and dura mater; then, the ethmoidal canals were located and measured in relation to the anterior wall of the sphenoid sinus and between the ethmoidal canals, followed by removal of their content for histological analysis.Results Vessels were present in 75% of the left anterior ethmoidal canals, 70% of the left posterior ethmoidal canals, 75% of the left middle ethmoidal canals, 85% of the right anterior ethmoid canals, and 64.5% of the right posterior ethmoid canals; 50% of the right middle ethmoidal canals contained one vessel.Conclusion The ethmoidal canal does not necessarily contain an ethmoidal artery. Studies with a larger sample should be performed to quantify the correct proportion of arteries and ethmoidal canals.
  • article 711 Citação(ões) na Scopus
    International Consensus Statement on Allergy and Rhinology: Rhinosinusitis
    (2016) ORLANDI, Richard R.; KINGDOM, Todd T.; HWANG, Peter H.; SMITH, Timothy L.; ALT, Jeremiah A.; BAROODY, Fuad M.; BATRA, Pete S.; BERNAL-SPREKELSEN, Manuel; BHATTACHARYYA, Neil; CHANDRA, Rakesh K.; CHIU, Alexander; CITARDI, Martin J.; COHEN, Noam A.; DELGAUDIO, John; DESROSIERS, Martin; DHONG, Hun-Jong; DOUGLAS, Richard; FERGUSON, Berrylin; FOKKENS, Wytske J.; GEORGALAS, Christos; GOLDBERG, Andrew; GOSEPATH, Jan; HAMILOS, Daniel L.; HAN, Joseph K.; HARVEY, Richard; HELLINGS, Peter; HOPKINS, Claire; JANKOWSKI, Roger; JAVER, Amin R.; KERN, Robert; KOUNTAKIS, Stilianos; KOWALSKI, Marek L.; LANE, Andrew; LANZA, Donald C.; LEBOWITZ, Richard; LEE, Heung-Man; LIN, Sandra Y.; LUND, Valerie; LUONG, Amber; MANN, Wolf; MARPLE, Bradley F.; MCMAINS, Kevin C.; METSON, Ralph; NACLERIO, Robert; NAYAK, Jayakar V.; OTORI, Nobuyoshi; PALMER, James N.; PARIKH, Sanjay R.; PASSALI, Desiderio; PETERS, Anju; PICCIRILLO, Jay; POETKER, David M.; PSALTIS, Alkis J.; RAMADAN, Hassan H.; RAMAKRISHNAN, Vijay R.; RIECHELMANN, Herbert; ROH, Hwan-Jung; RUDMIK, Luke; SACKS, Raymond; SCHLOSSER, Rodney J.; SENIOR, Brent A.; SINDWANI, Raj; STANKIEWICZ, James A.; STEWART, Michael; TAN, Bruce K.; TOSKALA, Elina; VOEGELS, Richard; WANG, De Yun; WEITZEL, Erik K.; WISE, Sarah; WOODWORTH, Bradford A.; WORMALD, Peter-John; WRIGHT, Erin D.; ZHOU, Bing; KENNEDY, David W.
    BackgroundThe body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). MethodsEvidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. ResultsThe resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AECRS), and pediatric RS. ConclusionAs a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too often the foundation upon which these recommendations are based is comprised of lower-level evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed.
  • article 412 Citação(ões) na Scopus
    International consensus statement on allergy and rhinology: rhinosinusitis 2021
    (2021) ORLANDI, Richard R.; KINGDOM, Todd T.; SMITH, Timothy L.; BLEIER, Benjamin; DECONDE, Adam; LUONG, Amber U.; POETKER, David M.; SOLER, Zachary; WELCH, Kevin C.; WISE, Sarah K.; ADAPPA, Nithin; ALT, Jeremiah A.; ANSELMO-LIMA, Wilma Terezinha; BACHERT, Claus; BAROODY, Fuad M.; BATRA, Pete S.; BERNAL-SPREKELSEN, Manuel; BESWICK, Daniel; BHATTACHARYYA, Neil; CHANDRA, Rakesh K.; CHANG, Eugene H.; CHIU, Alexander; CHOWDHURY, Naweed; CITARDI, Martin J.; COHEN, Noam A.; CONLEY, David B.; DELGAUDIO, John; DESROSIERS, Martin; DOUGLAS, Richard; ELOY, Jean Anderson; FOKKENS, Wytske J.; GRAY, Stacey T.; GUDIS, David A.; HAMILOS, Daniel L.; HAN, Joseph K.; HARVEY, Richard; HELLINGS, Peter; HOLBROOK, Eric H.; HOPKINS, Claire; HWANG, Peter; JAVER, Amin R.; JIANG, Rong-San; KENNEDY, David; KERN, Robert; LAIDLAW, Tanya; LAL, Devyani; LANE, Andrew; LEE, Heung-Man; LEE, Jivianne T.; LEVY, Joshua M.; LIN, Sandra Y.; LUND, Valerie; MCMAINS, Kevin C.; METSON, Ralph; MULLOL, Joaquim; NACLERIO, Robert; OAKLEY, Gretchen; OTORI, Nobuyoshi; PALMER, James N.; PARIKH, Sanjay R.; PASSALI, Desiderio; PATEL, Zara; PETERS, Anju; PHILPOTT, Carl; PSALTIS, Alkis J.; RAMAKRISHNAN, Vijay R.; RAMANATHAN, Murugappan; ROH, Hwan-Jung; RUDMIK, Luke; SACKS, Raymond; SCHLOSSER, Rodney J.; SEDAGHAT, Ahmad R.; SENIOR, Brent A.; SINDWANI, Raj; SMITH, Kristine; SNIDVONGS, Kornkiat; STEWART, Michael; SUH, Jeffrey D.; TAN, Bruce K.; TURNER, Justin H.; DRUNEN, Cornelis M.; VOEGELS, Richard; WANG, De Yun; WOODWORTH, Bradford A.; WORMALD, Peter-John; WRIGHT, Erin D.; YAN, Carol; ZHANG, Luo; ZHOU, Bing
    Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR-RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR-RS-2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence-based findings of the document. Methods: ICAR-RS presents over 180 topics in the forms of evidence-based reviews with recommendations (EBRRs), evidence-based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR-RS-2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence-based management algorithm is provided. Conclusion: This ICAR-RS-2021 executive summary provides a compilation of the evidence-based recommendations for medical and surgical treatment of the most common forms of RS.
  • article 18 Citação(ões) na Scopus
    Reboot surgery for chronic rhinosinusitis with nasal polyposis: recurrence and smell kinetics
    (2022) GOMES, Sara Costa; CAVALIERE, Carlo; MASIERI, Simonetta; ZELE, Thibaut Van; GEVAERT, Philippe; HOLTAPPELS, Gabriele; ZHANG, Nan; RAMASAMY, Pathmanaban; VOEGELS, Richard Louis; BACHERT, Claus
    Objective To evaluate the time for recovery of the sense of smell in patients with CRSwNP who underwent Reboot surgery compared to patients undergoing ESS in a long-term follow-up study. Methods Data were collected retrospectively from 168 patients with severe uncontrolled CRSwNP, who underwent revision surgery, either as Extended Endoscopic Sinus Surgery (Reboot, 140 patients) or as regular Endoscopic Sinus Surgery (ESS, 28 patients) between January 1, 2014, and December 31, 2015, aiming to compare the outcome of surgeries after 2 years of follow-up. Sense of smell was scored as judged by the patient using scores 0 to 3 reflecting a percentage estimate of remaining smell. Results Smell improved similarly in the Reboot and ESS groups over the first 9 months, which was maintained over 24 months in the Reboot, but not the ESS group (p = 0.007 after 18 months, p = 0.001 after 24 months). Furthermore, polyp recurrence rates were significantly lower in the Reboot group. Conclusion Reboot surgery significantly improved olfactory function and significantly reduced nasal polyp recurrence rates over 2 years post-operatively. Therefore, Reboot should be considered for patients with uncontrolled severe CRSwNP, specifically when ESS failed, to offer long-term smell and a polyp-free status.