JANE OBA
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Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
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- Management of inflammatory bowel disease patients in the COVID-19 pandemic era: a Brazilian tertiary referral center guidance(2020) QUEIROZ, Natalia Sousa Freitas; BARROS, Luisa Leite; AZEVEDO, Matheus Freitas Cardoso de; OBA, Jane; SOBRADO, Carlos Walter; CARLOS, Alexandre de Sousa; MILANI, Luciane Reis; SIPAHI, Aytan Miranda; DAMIAO, Aderson Omar Mourao CintraThe world is fighting the COVID-19 outbreak and health workers, including inflammatory bowel diseases specialists, have been challenged to address the specific clinical issues of their patients. We hereby summarize the current literature in the management of inflammatory bowel disease (IBD) patients during the COVID-19 pandemic era that support the rearrangement of our IBD unit and the clinical advice provided to our patients.
- Gastrointestinal manifestations and nutritional therapy during COVID-19 pandemic: a practical guide for pediatricians(2020) OBA, Jane; CARVALHO, Werther Brunow de; SILVA, Clovis Artur; DELGADO, Artur FigueiredoCoronavirus disease 2019 (COVID-19) is a disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has spread globally in pandemic proportions. Accumulative evidence suggests SARS-CoV-2 can be transmitted through the digestive system, the so-called fecal-oral route of transmission, and may induce several gastrointestinal manifestations. MEDLINE (R) and Embase databases were extensively searched for major clinical manifestations of gastrointestinal involvement in children and adolescents with COVID-19 reported in medical literature, and for nutritional therapy-related data. Findings and recommendations were pragmatically described to facilitate overall pediatric approach. A total of 196 studies addressing gastrointestinal or nutritional aspects associated with the global COVID-19 pandemic were found. Of these, only 17 focused specifically on pediatric patients with regard to aforementioned gastrointestinal or nutritional aspects. Most articles were descriptive and six addressed guidelines, established protocols, or expert opinions. Children and adolescents with gastrointestinal symptoms, such as nausea, vomiting and diarrhea, should be seriously suspected of COVID-19. Gastrointestinal signs and symptoms may occur in 3% to 79% of children, adolescents and adults with COVID-19, and are more common in severe cases. These include diarrhea (2% to 50%), anorexia (40% to 50%), vomiting (4% to 67%), nausea (1% to 30%), abdominal pain (2% to 6%) and gastrointestinal bleeding (4% to 14%). Patients with inflammatory bowel disease or chronic liver disease are not at greater risk of infection by SARS-CoV-2 relative to the general population. Nutritional support plays an important role in treatment of pediatric patients, particularly those with severe or critical forms of the disease. The digestive system may be a potential route of COVID-19 transmission. Further research is needed to determine whether the fecal-oral route may be involved in viral spread. Nutritional therapy is vital to prevent malnutrition and sarcopenia in severe cases.
conferenceObject Epidemiological profile and long-term outcomes from a large PSC-IBD cohort(2020) CAON, A. E.; MARTINS, C.; CRUZ, M.; BARROS, L. Leite; AZEVEDO, M.; QUEIROZ, N.; CARLOS, A.; MILANE, L.; OBA, J.; BRAGA, M.; SIPAHI, A.; DAMIAO, A.; CANCADO, E.conferenceObject Health-related quality of life in adolescents and young adults (AYA) with inflammatory bowel disease and its correlations with demographic, clinical, laboratory and therapeutic evaluations(2020) OBA, J.; DEBONI, M.; TOMA, R.; SOBRADO, C.; AZEVEDO, M.; CARLOS, A.; BORBA, M.; DAMIAO, A.; CARRILHO, F.; SILVA, C.