RENATO LUIZ MARCHETTI
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina - Médico
15 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 15
bookPart Epilepsia e transtornos mentais relacionados(2019) MARCHETTI, Renato Luiz; GALLUCCI NETO, José; LINS, Thiago Viegas GomesbookPart A entrevista clínica psiquiátrica(2019) MARCHETTI, Renato Luiz; GALLUCCI NETO, José; CROCI, Marcos Signoretti; BRAñAS, Marcelo José Abduch AdasbookPart Consciência e atenção(2021) NOGUEIRA, Juliana Hangai Vaz Guimarães; MAZZOCO, Marina Flaborea; DIAS, Yuri Tebelskis Nunes; GALLUCCI NETO, José; MARCHETTI, Renato Luiz- Ictal SPECT in Psychogenic Nonepileptic and Epileptic Seizures(2021) GALLUCCI-NETO, Jose; BRUNONI, Andre Russowsky; ONO, Carla Rachel; FIORE, Lia Arno; CASTRO, Luiz Henrique Martins; MARCHETTI, Renato LuizBackground: Psychogenic nonepileptic seizures (PNES) are a common and debilitating problem in patients with epilepsy. They can be virtually indistinguishable from epileptic seizures, demanding video-electroencaphalogram monitoring, which is costly and not widely available, for differential diagnosis. Specific functional brain correlates of PNES have not been demonstrated so far. We hypothesized that PNES and epileptic seizures have distinct brain activation patterns, assessed by functional neuroimaging during ictal events of both conditions. Objective: Compare ictal brain activation patterns of PNES and epileptic seizures using single-photon emission computerized tomography. Methods: We prospectively assessed brain functional activation using single-photon emission computerized tomography 99mTc-ethyl cysteinate dimer in 26 patients with PNES, confirmed by trained psychiatrists in epileptology, who had their seizures induced by provocative tests compared with 22 age- and sex-matched subjects with temporal lobe epilepsy who underwent prolonged intensive video-electroencaphalogram monitoring. Results: In PNES patients compared with temporal lobe epilepsy group, we found a consistent increase in regional cerebral blood flow in the right precuneus (Brodmann area 7; P = 0.003) and right posterior cingulate cortex (Brodmann area 31; P = 0.001), as well as a decrease in regional cerebral blood flow in the right amygdala (P = 0.027). Conclusions: Activation of default mode network brain areas and temporoparietal junction may be a distinct feature of ictal PNES and could be explained by a disruption between movement prediction input and sensory outcome. Such information mismatch might be the neurobiological underpinning of dissociative episodes.
bookPart Epilepsia e crises não epilépticas psicogênicas(2015) MARCHETTI, Renato Luiz; GALLUCCI NETO, JosébookPart Transtornos mentais associados à epilepsia(2023) LINS, Thiago Viegas Gomes; CHENAUD NETO, Paulo; MARCHETTI, Renato LuizbookPart Anamnese psiquiátrica no adulto(2021) SANT, Renato Del; MARCHETTI, Renato Luiz- Immunization stress-related responses presenting as psychogenic non-epileptic seizures following HPV vaccination in Rio Branco, Brazil(2020) MARCHETTI, Renato Luiz; GALLUCCI-NETO, Jose; KURCGANT, Daniela; PROENCA, Inah Carolina Galatro Faria; VALIENGO, Leandro da Costa Lane; FIORE, Lia Arno; PINTO, Lecio Figueira; MARANHAO, Ana Goretti Kalume; OLIVEIRA, Maria Tereza da Costa; OLIVEIRA, Lucia Helena deImportance: The absence of a positive diagnosis of psychogenic non-epileptic seizures (PNES) in immunization stress-related response (ISRR) clusters may have not only a direct impact on affected patients' health but may also reduce compliance to national vaccination programs. It is therefore crucial to develop efficient diagnostic tools and a feasible proposal for proper communication and treatment of ISRR. Purpose: To explore the psychogenic nature of patients' convulsive seizures in a suspected outbreak of an ISRR cluster following human papillomavirus vaccination in Rio Branco, Brazil. Methods: Twelve patients with convulsive seizures were submitted to prolonged intensive videoelectroencephalography monitoring, brain magnetic resonance imaging, cerebrospinal fluid diagnostic testing, laboratory subsidiary examinations, and complete neurological and psychiatric evaluations. Results: Ten patients received the positive diagnosis of PNES, and two patients received the diagnosis of idiopathic generalized epilepsy. No biological association was found between the HPV vaccine and the clinical problems presented by the patients. Conclusions: Prolonged VEEG monitoring can contribute significantly to the positive diagnosis of PNES in ISRR clusters and to avoid hesitancy to vaccinate.
bookPart Sindromes mentais orgânicas(2021) PROENçA, Inah Carolina Galatro Faria; MARCHETTI, Renato Luiz- Emotional trauma and abuse in patients with psychogenic nonepileptic seizures(2011) PROENCA, Inah Carolina Galatro Faria; CASTRO, Luiz Henrique Martins; JORGE, Carmen Lisa; MARCHETTI, Renato LuizA history of childhood trauma and the presence of dissociative phenomena are considered to be the most important risk factors for psychogenic nonepileptic seizure disorder (PNESD). This case-control study investigated 20 patients with PNESD and 20 with temporal lobe epilepsy (TLE) diagnosed by video/EEG monitoring who were matched for gender and age. Patients with both conditions were not included in the study. Groups were evaluated for age at onset and at diagnosis, worst lifetime weekly seizure frequency, trauma history, and presence of dissociative phenomena. Age at onset (P = 0.007) and age at diagnosis (P < 0.001) were significantly higher in the PNESD group than the control group, as were the scores on the Dissociative Experiences Scale (P < 0.001) and Childhood Trauma Questionnaire (P = 0.014). Only the differences in scores on the Childhood Trauma Questionnaire subscales Emotional Neglect (P = 0.013) and Emotional Abuse (P = 0.014) reached statistical significance. Dissociative phenomena and a reported history of childhood trauma are more common in patients with PNESD than in those with TLE. However, only emotional neglect and abuse were associated with PNESD in this study.