FREDERICO LEON ARRABAL FERNANDES
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
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conferenceObject Dynamic hyperinflation and exercise limitation in obese asthmatics(2014) FERREIRA, Palmira G.; FREITAS, Patricia D.; SILVA, Aline G.; STELMACH, Rafael; CUKIER, Alberto; FERNANDES, Frederico L. A.; MARTINS, Milton A.; CARVALHO, Celso R. F.- Experimentation with and knowledge regarding water-pipe tobacco smoking among medical students at a major university in Brazil(2014) MARTINS, Stella Regina; PACELI, Renato Batista; BUSSACOS, Marco Antonio; FERNANDES, Frederico Leon Arrabal; PRADO, Gustavo Faibischew; LOMBARDI, Elisa Maria Siqueira; TERRA-FILHO, Mario; SANTOS, Ubiratan PaulaObjective: Water-pipe tobacco smoking is becoming increasingly more common among young people. The objective of this study was to estimate the prevalence of the use of water pipes and other forms of tobacco use, including cigarette smoking, among medical students, as well as to examine the attitudes, beliefs, and knowledge of those students regarding this issue. Methods: We administered a questionnaire to students enrolled in the University of Sao Paulo School of Medicine, in Sao Paulo, Brazil. The respondents were evaluated in their third and sixth years of medical school, between 2008 and 2013. Comparisons were drawn between the two years. Results: We evaluated 586 completed questionnaires. Overall, the prevalence of current cigarette smokers was low, with a decline among males (9.78% vs. 5.26%) and an increase among females (1.43% vs. 2.65%) in the 3rd and 6th year, respectively. All respondents believed that health professionals should advise patients to quit smoking. However, few of the medical students who smoked received physician advice to quit. Experimentation with other forms of tobacco use was more common among males (p<0.0001). Despite their knowledge of its harmful effects, students experimented with water-pipe tobacco smoking in high proportions (47.32% and 46.75% of the third- and sixth-year students, respectively). Conclusions: The prevalence of experimentation with water-pipe tobacco smoking and other forms of tobacco use is high among aspiring physicians. Our findings highlight the need for better preventive education programs at medical schools, not only to protect the health of aspiring physicians but also to help them meet the challenge posed by this new epidemic.
conferenceObject Clinical, functional and microbiological characteristics of an adult br Tian cystic fibrosis population(2014) RACHED, Samia Zahi; ATHANAZIO, Rodrigo; MAIORANO, Maria Cecilia Nieves Teixeira; FERNANDES, Frederico; CARVALHO-PINTO, Regina; CUKIER, Alberto; STELMACH, Rafael- Barriers associated with reduced physical activity in COPD patients(2014) AMORIM, Priscila Batista; STELMACH, Rafael; CARVALHO, Celso Ricardo Fernandes; FERNANDES, Frederico Leon Arrabal; CARVALHO-PINTO, Regina Maria; CUKIER, AlbertoObjective: To evaluate the ability of COPD patients to perform activities of daily living (ADL); to identify barriers that prevent these individuals from performing ADL; and to correlate those barriers with dyspnea severity, six-minute walk test (6MWT), and an ADL limitation score. Methods: In COPD patients and healthy, age-matched controls, the number of steps, the distance walked, and walking time were recorded with a triaxial accelerometer, for seven consecutive days. A questionnaire regarding perceived barriers and the London Chest Activity of Daily Living (LCADL) scale were used in order to identify the factors that prevent the performance of ADL. The severity of dyspnea was assessed with two scales, whereas submaximal exercise capacity was determined on the basis of the 6MWT. Results: We evaluated 40 COPD patients and 40 controls. In comparison with the control values, the mean walk time was significantly shorter for COPD patients (68.5 +/- 25.8 min/day vs. 105.2 +/- 49.4 min/ day; p < 0.001), as was the distance walked (3.9 +/- 1.9 km/day vs. 6.4 +/- 3.2 km/day; p < 0.001). The COPD patients also walked fewer steps/day. The most common self-reported barriers to performing ADL were lack of infrastructure, social influences, and lack of willpower. The 6MWT distance correlated with the results obtained with the accelerometer but not with the LCADL scale results. Conclusions: Patients with COPD are less active than are healthy adults of a comparable age. Physical inactivity and the barriers to performing ADL have immediate implications for clinical practice, calling for early intervention measures.
conferenceObject Quantitative Airway Wall Thickness In Severe Asthmatic Patients: An Useful Prognostic Tool But Not Predictor To Therapy(2014) ATHANAZIO, R. A.; CARVALHO-PINTO, R.; JASINOWODOLINSKI, D.; RACHED, S. Z.; MAIORANO, M. C.; FERNANDES, F. L. A.; RABE, K.; CUKIER, A.; STELMACH, R.conferenceObject A Case Of Association Of Pulmonary Actinomycosis And Chronic Cavitary Pulmonary Aspergillosis(2014) RACHED, S. Z.; MAIORANO, M. C. N. T.; ALMEIDA, G. Eler De; ATHANAZIO, R.; CARVALHO-PINTO, R.; FERNANDES, F. Leon Arrabal; STELMACH, R.; CUKIER, A.conferenceObject Mucoid Impaction Can Predict Oral Corticosteroids Response In Severe Asthmatic Patients(2014) ATHANAZIO, R. A.; CARVALHO-PINTO, R.; JASINOWODOLINSKI, D.; FERNANDES, F. L. A.; MAIORANO, M. C.; RACHED, S. Z.; RABE, K. F.; CUKIER, A.; STELMACH, R.article 0 Citação(ões) na Scopus Performance during cardiopulmonary exercise test and quality of life of long-distance elderly runners and of non-exerciser elderly(2014) CARDOSO, A.; GREVE, J. M. D.; SANTOS-SILVA, P. R.; ARRABAL, F. F. Leon; SANTOS, U. De PaulaAim. Regular physical exercises are associated to decreased morbidity and mortality, but their relationship with quality of life perception is still not well established. The aim of this paper was to compare cardiopulmonary exercise indicators of functional performance and quality of life (QOL) between a group of untrained elderly (GUE) and a group of trained elderly (GTE) in long-distance running. Methods. GUE was made up of 19 individuals with mean age of 73.5 +/- 6.4 years and GTE by 27 trained elderly with mean age of 73.1 +/- 4.3 years. All were submitted to cardiopulmonary and metabolic evaluation by expired gases analysis. Maximum physical capacity was determined on a motor-driven treadmill with continuous graded protocol and fixed slope of 1%. Quality of Life was evaluated in four domains (physical, psychological, social relations and environment) by Whoqol-Bref questionnaire (WHO) and quantified by total score for each domain. Results. At maximal oxygen intake, GUE and GTE presented: VO2max: 27.0 +/- 5.4 vs. 38.1 +/- 4.5 mL/[kg.min] (P<0.001); O-2 pulse: 11.7 +/- 3.0 vs. 15.5 +/- 2.4 mL/bpm (P<0.001); running speed: 9.7 +/- 2.5 vs. 13.8 +/- 1.7 km/h (P<0.001) and tolerance time: 9.6 +/- 2.9 vs. 14.8 +/- 4.4 mm (P<0.001). QOL measured by Whoqol-Bref questionnaire in four domains for GUE and GTE was respectively: physical: 75.6 +/- 13.6 vs. 80.6 +/- 14.2 (P=0.210), psychological: 79.2 +/- 11.3 vs. 79.2 +/- 13.8 (P=0.893), social relations: 74.6 +/- 14.3 vs. 74.7 +/- 19.1 (P=0.726), environment: 61.4 +/- 15.9 vs. 69.0 +/- 15.5 (P=0.131). Conclusion. GTE cardiopulmonary performance was better as compared to GUE, and QOL of the elderly from both groups was not associated to cardiopulmonary exercise test performance.