RENATA MOTA MAMEDE CARVALLO

(Fonte: Lattes)
Índice h a partir de 2011
10
Lattes
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Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, Faculdade de Medicina - Docente
LIM/34 - Laboratório de Ciências da Reabilitação, Hospital das Clínicas, Faculdade de Medicina

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  • article 17 Citação(ões) na Scopus
    A systematic review of mercury ototoxicity
    (2012) HOSHINO, Ana Cristina Hiromi; FERREIRA, Heloisa Pacheco; MALM, Olaf; CARVALLO, Renata Mamede; CAMARA, Volney Magalhaes
    Mercury is neurotoxic, and numerous studies have confirmed its ototoxic effect. However, the diagnosis and follow-up of mercury exposure require understanding the pathophysiology of the chemical substance. Based on a systematic literature review, this study aimed to demonstrate whether mercury is ototoxic and to analyze its mechanism of action on the peripheral and central auditory system, in order to contribute to the diagnosis and follow-up of exposure. This was a systematic review of studies published on the effects of mercury exposure on the auditory system. The full text of the studies and their methodological quality were analyzed. The review identified 108 studies published on the theme, of which 28 met the inclusion criteria. All the articles in the analysis showed that mercury exposure is ototoxic and produces peripheral and/or central damage. Acute and long-term exposure produces irreversible damage to the central auditory system. Biomarkers were unable to predict the relationship between degree of mercury poisoning and degree of lesion in the auditory system.
  • article 2 Citação(ões) na Scopus
    Peripheral hearing in Parkinson's disease: a systematic review
    (2023) LEME, Mariana S.; SANCHES, Seisse G. G.; CARVALLO, Renata M. M.
    Objective To investigate the implications of Parkinson's disease (PD) in the peripheral auditory system, a systematic survey of the scientific literature was conducted. Design Systematic review. Study sample An electronic search of the non-gray literature in the last decade was conducted using the digital databases MEDLINE (R) (PubMed interface), LILACS (R) (Virtual Health Library), Web of Science (R) (CAPES publications portal), and SciELO (R). Studies addressing peripheral auditory function as part of the range of nonmotor PD symptoms were selected for analysis. Results Pure tone audiometry data suggested that sensorineural hearing loss was more severe in the PD population than in the control groups. The effects of PD on cochlear function were evidenced by a decrease in the levels of otoacoustic emissions. Conclusions Sensorineural hearing loss and cochlear impairment are more severe in the PD population than in the control groups. Additional studies are recommended to further understand the characteristics of the peripheral auditory system in PD patients, which constitutes an emerging subject in the scientific literature.