MARIA NOTOMI SATO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Dermatologia, Faculdade de Medicina - Docente
LIM/56 - Laboratório de Investigação em Dermatologia e Imunodeficiências, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/56 - Laboratório de Investigação em Dermatologia e Imunodeficiências, Hospital das Clínicas, Faculdade de Medicina - Líder
24 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 24
conferenceObject PRECONCEPTIONAL IMMUNIZATION WITH OVA CAN INDUCE OFFSPRING IL-17 SECRETING B CELLS WITH REGULATORY POTENTIAL (B17): A POSSIBLE ROLE IN OFFSPRING ALLERGY INHIBITION.(2015) LIRA, A. A. L.; DE-OLIVEIRA, M. G.; DUARTE, A. J. S.; SATO, M. N.; VICTOR, J. R.- Effect of exercise training on Treg cell response in severe COPD individuals: a randomized and controlled trial(2022) ITO, J. T.; OLIVEIRA, L. M.; V, L. Alves; XAVIER, R. F.; SATO, M. N.; CARVALHO, C. R. F.; TIBERIO, I. F. L. C.; LOPES, F. D. T. Q. S.
conferenceObject IgG from atopic dermatitis patients induces IL-17 and IL-10 production in infant intra-thymic TCD4 and TCD8 cells(2018) SGNOTTO, F. R.; OLIVEIRA, M. G.; LIRA, A. A. L.; INOUE, A. H. S.; TITZ, T. O.; ORFALI, R. L.; BENTO-DE-SOUZA, L.; SATO, M. N.; AOKI, V.; DUARTE, A. J. S.; VICTOR, J. R.conferenceObject Atopic dermatitis in adults: Augmented circulating IgG4 and IgE antibodies against Staphylococcus aureus enterotoxin B(2013) ORFALI, R. L.; SATO, M. N.; SANTOS, V. G. Dos; TITZ, T. O.; DUARTE, A. S.; TAKAOKA, R.; AOKI, V.The aim of this study was to evaluate the profile of anti-Staphylococcus aureus enterotoxin B (SEB) antibody (Ab) response in adults with AD. We selected 38 patients diagnosed as AD (Hanifin & Rajka's criteria), aged between 18 and 65, and 26 healthy controls (HC), aged between 20 and 47 years. Severity of the disease was established according to EASI (Eczema Area and Severity Index) and patients were graded as mild (28%), moderate (58%) and severe (14%). Sera were assessed for IgG subclasses, IgA, IgM and IgE against SEB by ELISA. The humoral response in AD patients to SEB showed elevated circulating IgE and IgG4 levels (p < 0.05 and p δ 0.001, respectively), and decreased IgA and IgM levels (p < 0.05). Severity of atopic dermatitis was related with low IgG1 and IgG3 levels (p < 0.05), and high IgE antibody response (p < 0.05) to SEB. Interestingly, absence of IgE and IgG1 response to SEB was seen in some AD patients (26.3% and 18.4% respectively). In AD, the immunoglobulin-related subtype Th2 lymphocytes, such as IgE and IgG4, appear to be relevant in the response to superantigens. These results emphasize an altered pattern of Ab response to SEB in AD, which is impaired according the disease severity.conferenceObject Staphylococcus aureus enterotoxins modulate IL-22-secreting cells in adults with atopic dermatitis(2018) ORFALI, R. L.; OLIVEIRA, L. M. S.; LIMA, J. F.; CARVALHO, G. C.; RAMOS, Y. A. L.; PEREIRA, N. Z.; VIEIRA, N. P.; ZANIBONI, M. C.; SATO, M. N.; AOKI, V.- The imbalance between subpopulations of regulatory T (TREG) Cells at different stages of chronic obstructive pulmonary disease (COPD)(2023) ALVES, Luan Henrique Vasconcelos; A, Juliana Tiyaki Ito; OLIVEIRA, Luana Mendonca De; TIBERIO, Iolanda Lopes Calvo; STELMACH, Rafael; SATO, Maria Notomi; ALMEIDA, Francine Maria; LOPES, Fernanda Degobbi Tenorio Quirino dos Santos
- Mechanisms underlying the role of exercise training as part of a weight loss program on asthma control in obese asthmatics(2016) FREITAS, Patricia; FERREIRA, Palmira G.; SILVA, Aline G.; STELMACH, Rafael; CARVALHO-PINTO, Regina; FERNANDES, Frederico L. A.; MARTINS, Milton A.; MANCINI, Marcio C.; SATO, Maria N.; CARVALHO, Celso R. F.
- HIV-I INHIBITION BY IFN-I ADJUVANTS IN NEONATAL MACROPHAGES(2019) PIETROBON, Anna Julia; YOSHIKAWA, Fabio Seiti Yamada; OLIVEIRA, Luana De Mendonca; PEREIRA, Natalli Zanete; SOUZA, Tais Aparecida Matozo De; BARGIERI, Bruna Cunha De Alencar; DUARTE, Alberto Jose Da Silva; SATO, Maria Notomi
- Intracellular mechanisms of Th17/Treg differentiation in mild and moderate COPD patients(2019) LOURENCO, Juliana Dias; SILVA, Larissa Emidio De Franca; GENARO, Isabella Santos De; ITO, Juliana Tiyaki; PIETROBON, Anna Julia; SATO, Maria Notomi; GROSS, Jefferson Luiz; NEGRI, Elnara Marcia; BARBEIRO, Denise Frediani; TEODORO, Walcy Paganelli Rosolia; MIRANDA, Jurandir Tomaz De; SARAIVA-ROMANHOLO, Beatriz Mangueira; VIEIRA, Rodolfo De Paula; LOPES, Fernanda Degobbi Tenorio Quirino Dos Santos
conferenceObject Atopic dermatitis in adults: Association of impaired of CD38 and CD69 expression and eosinophilia(2014) TITZ, Tiago de Oliveira; LOLLO, Camila de; SATO, Maria Notomi; ORFALI, Raquel Leao; AOKI, Valeria; SANTOS, Vanessa Goncalves dos
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