MONICA KAYO

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Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina

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Autor e Coautores FMUSP-HC Normalizados: DEBORA LUCIANA MELZER RIBEIRO ×

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Agora exibindo 1 - 3 de 3
  • bookPart
    Tratamento da esquizofrenia
    (2021) LOUZã, Mário Rodrigues; KAYO, Monica; VIZZOTTO, Adriana Dias Barbosa; MELZER-RIBEIRO, Débora Luciana; SARNO, Elaine Scapaticio Di; OLIVEIRA, Graça Maria Ramos de; NAPOLITANO, Isabel Cristina; GOMES, Mônica Lopes; ELKIS, Helio
  • article 9 Citação(ões) na Scopus
    Efficacy of electroconvulsive therapy augmentation for partial response to clozapine: a pilot randomized ECT - sham controlled trial
    (2017) MELZER-RIBEIRO, Debora Luciana; RIGONATTI, Sergio Paulo; KAYO, Monica; AVRICHIR, Belquiz S.; RIBEIRO, Rafael Bernardon; SANTOS, Bernardo dos; FORTES, Marisa; ELKIS, Helio
    Background: Thirty percent of schizophrenia patients are treatment-resistant. Objective: This is a single-blinded sham-controlled trial to assess the efficacy of electroconvulsive therapy (ECT) as augmentation strategy in patients with clozapine-resistant schizophrenia. Methods: Twenty three subjects were randomly assigned to 12 sessions of ECT (N = 13) or placebo (Sham ECT) (N = 10). The primary outcome was improvement on psychotic symptoms as measured by the mean reduction of the PANSS positive subscale. The assessments were performed by blind raters. Results: At baseline both groups were similar, except for negative and total symptoms of the PANSS, which were higher in the Sham group. At the endpoint both groups had a significant decrease from basal score. In the ECT group the PANSS total score decreased 8.78%, from 81.23 to 74.75 (p - 0.042), while the positive subscale had a mean reduction of 19% (19.31 to 16.17, p = 0.006). In the Sham group, the mean reduction of PANSS total score was 15.27% (96.80 to 87.43; p = 0.036), and the PANSS positive subscale decreased 27.81% (22.90 to 19.14, p = 0.008). The CGI score in ECT group decreased 23.0% (5.23 to 4.17; p = 0.001) and decreased 24.31% in the Sham ECT group (5.80 to 4.86; p = 0.004). Discussion: In this pilot study, we found no difference between the groups.
  • conferenceObject
    PILOT DOUBLE BLIND, PLACEBO CONTROLLED AND RANDOMIZED STUDY TO ASSESS ELECTROCONVULSIVE THERAPY EFFICACY AS AUGMENTING STRATEGY TO CLOZAPINE IN SUPER-REFRACTORY SCHIZOPHRENIA
    (2015) MELZER-RIBEIRO, Debora Luciana; RIGONATTI, Sergio Paulo; KAYO, Monica; RIBEIRO, Rafael Bernardon; AVRICHIR, Belquiz; FORTES, Marisa; CAMARGO, Maria Emilia; ELKIS, Helio