JOEL CLAUDIO HEIMANN
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Clínica Médica, Faculdade de Medicina - Docente
LIM/16 - Laboratório de Fisiopatologia Renal, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/16 - Laboratório de Fisiopatologia Renal, Hospital das Clínicas, Faculdade de Medicina - Líder
20 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 20
conferenceObject Fine particulate matter in the inspired air within the limits recommended by WHO alters placental structure(2014) SOTO, Sonia; LOPES, Karen; VERAS, Mariana; HEIMANN, JoelconferenceObject Myocardial AT1 gene expression is increased in a model of left ventricular hypertrophy induced by high salt intake(2013) PEREIRA, Rafael Canavel; KATAYAMA, Isis Akemi; HEIMANN, Joel ClaudioObjective: To evaluate gene expression of the renin-angiotensin system components in a model of left ventricular hypertrophy induced by high salt intake demonstrated in a previous study. Methods: Wistar rats were fed normal (NS1.3% NaCl) or high (HS 8%) salt diet since weaning. From the 7th week of age, two HS subgroups received hydralazine or losartan (HZ 15 and LOS 20mg/kg/day). Angiotensinogen, renin, ACE, ACE2, AT1 and AT2 gene expression in left ventricle were measured. Data are reported as mean±SEM. Means in row with superscripts without a common letter differ, P<0.05. Conclusion: High salt intake increases AT1 gene expression, however it is prevented by losartan treatment.conferenceObject Effect of an angiotensin II type 2 receptor agonist on myocardial hypertrophy and fibrosis induced by high salt diet(2017) DOPONA, Ellen Priscila Brito; ROCHA, Veronica Favoni; OLIVEIRA, Ivone Braga de; FURUKAWA, Luzia Naoko Shinohara; HEIMANN, Joel ClaudioconferenceObject Small litter size at birth is associated with insulin resistance and low energy expenditure in adulthood(2013) TAVARES, Neuziane Kloos Amorim; AGUIAR, Fernanda de Jesus; FURUKAWA, Luzia Naoko; HEIMANN, Joel ClaudioObjective: To evaluate the effect of litter size standardization at birth on adult metabolic parameters.Methods: Female Wistar rats became pregnant at 12 weeks of age. Offspring were divided into control(C), G8(8) and G4(4 newborns/litter) groups. At 12 weeks of age, food intake (FI,g/day), glucose (G,mg/dL), insulin (I,pM), cholesterol (Chol,mg/dL), triacylglycerols (TAG,mg/dL) levels, white and brown adipose tissue (BAT) masses (g/100g) adiposity index (AI,% body weight) were determined. Conclusion: Results suggest that changes in litter size is associated with energy balance, carbohydrate and lipid disorders, insulin resistance and alterations in blood pressure in adult male and female.conferenceObject Fine particulate matter in the air within the limits recommended by WHO alters placental structure(2015) SOTO, Sonia; MARCHESI, Guilherme; LOPES, Karen; VERAS, Mariana; HEIMANN, JoelconferenceObject Salt intake during pregnancy influences offspring organ growth(2014) PERES, Maria; OLIVEIRA, Ivone de; FURUKAWA, Luzia; GUIMARAES, Carina; HEIMANN, JoelconferenceObject Effects of exposure do air pollution on placental structure(2013) SOTO, Sonia de Fatima; LOPES, Karen; VERAS, Mariana Matera; HEIMANN, JoelconferenceObject Transgenerational Effects of High Salt Diet During Gestation(2016) PERES, Maria Angelica; OLIVEIRA, Ivone Braga de; FURUKAWA, Luzia Naoko Shinohara; HEIMANN, JoelconferenceObject Mitochondria function and structure in brown adipose tissue is influenced by maternal low salt intake during the perinatal period(2012) LOPES, Karen Lucasechi; SANTOS, Elisabete Alcantara Dos; FURUKAWA, Luzia Naoko Shinohara; HEIMANN, Joel ClaudioconferenceObject Lysine Specific Demethylase-1 Deficiency Accelerates the Development of Hypertension and Renal Damage During Long Term Sodium Intake(2019) KATAYAMA, Isis Akemi; CULLINANE, Danielle L.; WILLIAMS, Gordon H.; HEIMANN, Joel Claudio; POJOGA, Luminita H.