BARBARA MARIA IANNI
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
conferenceObject Whole exome sequencing of Chagas disease cardiomyopathy families reveals accumulation of rare variants in mitochondrial and inflammation-associated genes(2019) CUNHA-NETO, E.; MARQUET, S.; FRADE, A. Farage; FERREIRA, A. Mota; OUARHACHE, M.; IANNI, B.; FERREIRA, L. Rodrigues Pinto; RIGAUD, V. Oliveira-Carvalho; ALMEIDA, R. Ribeiro; CANDIDO, D.; TORRES, M.; GALLARDO, F.; FERNANDES, R.; MADY, C.; BUCK, P.; CARDOSO, C.; SANTOS-JUNIOR, O. R.; OLIVEIRA, L. C.; OLIVEIRA, C. D. L.; NUNES, M. do Carmo; ABEL, L.; KALIL, J.; RIBEIRO, A. L. P.; SABINO, E. C.; CHEVILLARD, C.conferenceObject SERUM ACTIVE COLLAGENASE FROM PATHOGENIC ARCHAEAL COLLAGENASE MAY CAUSE HEART FAILURE IN CHAGASIC PATIENTS(2019) HIGUCHI, Maria De Lourdes; KAWAKAMI, Joyce; IKEGAMI, Renata; REIS, Marcia; MORENO, Camila R.; PEREIRA, Jaqueline; IANNI, Barbara; BUCK, Paula; SANTOS, Marilia; BOCCHI, Edimar- IMPACT OF AIR POLLUTION ON MYOCARDIAL REMODELING IN CHAGA'S DISEASE(2019) FONSECA, Keila; PESSOA, Fernanda; MADY, Charles; HOTTA, Viviane; RIBEIRO, Orlando N.; FERNANDES, Fabio; IANNI, Barbara; SALDIVA, Paulo; RAMIRES, Felix
conferenceObject Three-dimensional Cardiac Mechanics for Prediction of Events in Chagas Disease(2019) HOTTA, Viviane T.; ABDUCH, Maria Cristina D.; VIEIRA, Marcelo Luiz C.; IANNI, Barbara M.; MADY, Charles; BOCCHI, Edimar A.conferenceObject Air pollution on myocardial remodeling in acute phase of Chagas disease in experimental model.(2019) FONSECA, Keila; PESSOA, F. G.; MADY, C.; HOTTA, V. T.; RIBEIRO, O. N.; FERNANDES, F.; IANNI, B. M.; SALDIVA, P. H. N.; RAMIRES, F. J. A.- Dysregulation of insulin levels in Chagas heart disease is associated with altered adipocytokine levels(2019) DABARIAN, Andre Luiz; MADY, Charles; BARBOSA-FERREIRA, Joao Marcos; IANNI, Barbara Maria; HOTTA, Viviane Tiemi; RAMIRES, Felix Jose Alvarez; LOPES, Heno Ferreira; BUCK, Paula de Cassia; PESSOA, Fernanda Gallinaro; FONSECA, Keila Cardoso Barbosa; NOGUEIRA, Adriana Ramos; FERNANDES, FabioMetabolic, inflammatory, and autonomic nervous system (ANS) dysfunction are present in patients with heart failure. However, whether these changes are due to left ventricular dysfunction or heart failure etiology is unknown. We evaluated metabolism and inflammatory activity in patients with idiopathic dilated cardiomyopathy (IDC) and Chagas cardiomyopathy (CHG) and their correlation with the ANS. Forty-six patients were divided into 3 groups: IDC, CHG, and control. We evaluated adiponectin, leptin, insulin, interleukin-6, and tumor necrosis factor-alpha. ANS were analyzed by heart rate variability in time and frequency domains on a 24-hour Holter monitor. Levels of glucose, cholesterol, leptin, and adiponectin did not show differences between groups. Insulin levels were lower in CHG group (5.4 +/- 3.3 mu U/mL) when compared with control (8.0 +/- 4.9 mu U/mL) and IDC (9.9 +/- 5.0 mu U/mL) groups (p = 0.007). Insulin was positively associated with LFr/HFr ratio (r = 0.562; p = 0.029) and with the LFr component (r = 0.562; p = 0.029) and negatively associated with adiponectin (r = -0.603; p = 0.017) in CHG group. The addition of an adiponectin unit reduced average insulin by 0.332 mu g/mL. Insulin levels were decreased in the CHG group when compared with the IDC group and were associated with ANS indexes and adiponectin levels.