ANA MARIA RIBEIRO DE CASTRO DUARTE

(Fonte: Lattes)
Índice h a partir de 2011
5
Projetos de Pesquisa
Unidades Organizacionais
LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina

Resultados de Busca

Agora exibindo 1 - 2 de 2
  • article 7 Citação(ões) na Scopus
    Atlantic Forest Malaria: A Review of More than 20 Years of Epidemiological Investigation
    (2021) BUERY, Julyana Cerqueira; ALENCAR, Filomena Euridice Carvalho de; DUARTE, Ana Maria Ribeiro de Castro; LOSS, Ana Carolina; VICENTE, Creuza Rachel; FERREIRA, Lucas Mendes; FUX, Blima; MEDEIROS, Marcia Melo; CRAVO, Pedro; AREZ, Ana Paula; CERUTTI JUNIOR, Crispim
    In the south and southeast regions of Brazil, cases of malaria occur outside the endemic Amazon region near the Atlantic Forest in some coastal states, where Plasmodium vivax is the recognized parasite. Characteristics of cases and vectors, especially Anopheles (Kerteszia) cruzii, raise the hypothesis of a zoonosis with simians as reservoirs. The present review aims to report on investigations of the disease over a 23-year period. Two main sources have provided epidemiological data: the behavior of Anopheles vectors and the genetic and immunological aspects of Plasmodium spp. obtained from humans, Alouatta simians, and Anopheles spp. mosquitoes. Anopheles (K.) cruzii is the most captured species in the forest canopy and is the recognized vector. The similarity between P. vivax and Plasmodium simium and that between Plasmodium malariae and Plasmodium brasilianum shared between simian and human hosts and the involvement of the same vector in the transmission to both hosts suggest interspecies transfer of the parasites. Finally, recent evidence points to the presence of Plasmodium falciparum in a silent cycle, detected only by molecular methods in asymptomatic individuals and An. (K.) cruzii. In the context of malaria elimination, it is paramount to assemble data about transmission in such non-endemic low-incidence areas.
  • article 5 Citação(ões) na Scopus
    Simian malaria: a narrative review on emergence, epidemiology andthreatto global malaria elimination
    (2023) FORNACE, Kimberly M.; LAPORTA, Gabriel Zorello; VYTHILINGHAM, Indra; CHUA, Trock Hing; CHUA, rock Hing; AHMED, Kamruddin; JEYAPRAKASAM, Nantha K.; DUARTE, Ana Maria Ribeiro de Castro; AMIR, Amirah; PHANG, Wei Kit; DRAKELEY, Chris; SALLUM, Maria Anice M.; LAU, Yee Ling
    Simian malaria from wild non-human primate populations is increasingly recognised as a public health threat and is now the main cause of human malaria in Malaysia and some regions of Brazil. In 2022, WHO changed malaria elimination certification guidelines to require non-negligible risks of simian malaria in people, leaving many countries with no pathway to elimination. We review the global distribution and drivers of simian malaria and identify priorities for diagnosis, treatment, surveillance, and control. Environmental change is driving closer interactions between humans and wildlife, with malaria parasites from non-human primates spilling over into human populations and human malaria parasites spilling back into wild non-human primate populations. These complex transmission cycles require new molecular and epidemiological approaches to track parasite spread. Current methods of malaria control are ineffective, with wildlife reservoirs and primarily outdoor-biting mosquito vectors urgently requiring the development of novel control strategies. Without these, simian malaria has the potential to undermine malaria elimination globally.