CARLOS EDUARDO ROCHITTE
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/64, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/64, Hospital das Clínicas, Faculdade de Medicina - Líder
18 resultados
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Agora exibindo 1 - 10 de 18
- Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations(2019) MAGALHAES, Tiago Augusto; CURY, Roberto Caldeira; CERCI, Rodrigo Julio; PARGA FILHO, Jose Rodrigues; GOTTLIEB, Ilan; NACIF, Marcelo Souto; PINTO, Ibraim Masciarelli; ROCHITTE, Carlos Eduardo; VILAS-BOAS, Fabio; SCHVARTZMAN, Paulo R.Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia.
- The Best Articles of 2022 in the Arquivos Brasileiros de Cardiologia and Revista Portuguesa de Cardiologia(2023) OLIVEIRA, Glaucia Maria Moraes de; FONTES-CARVALHO, Ricardo; CARDIM, Nuno; ROCHITTE, Carlos Eduardo
- Diagnostic accuracy of static CT perfusion for the detection of myocardial ischemia. A systematic review and meta-analysis(2016) SORGAARD, Mathias Holm; KOFOED, Klaus Fuglsang; LINDE, Jesper James; GEORGE, Richard Thomas; ROCHITTE, Carlos Eduardo; FEUCHTNER, Gudrun; LIMA, Joao A. C.; ABDULLA, JawdatObjectives: The aim of this study is to provide a meta-analysis of all published studies assessing the diagnostic accuracy of stress CT myocardial perfusion imaging (CTP) in patients suspected of or with known coronary artery disease. This analysis is limited to static stress CTP. Methods: Systematic literature review and meta-analysis of studies examining the diagnostic accuracy of static CTP imaging alone or combined with coronary CT angiography (CTA) in comparison to single photon emission computed tomography (SPECT), magnetic resonance perfusion (MRP), and/or invasive coronary angiography with and without fractional flow reserve (FFR). Results: The search revealed 19 eligible studies including 1188 patients. Pooled results showed that CTP had a good agreement with SPECT and MRP. On a per-patient level, sensitivity, specificity and AUC were 0.85 (95% CI: 0.70-0.93), 0.81 (95% CI: 0.59-0.93), 0.90 (95% CI: 0.87-0.92). On a per-artery level, sensitivity, specificity and AUC were 0.80 (95% CI: 0.67-0.88), 0.81 (95% CI: 0.72-0.88) and 0.87 (95% CI: 0.84-0.90). When invasive coronary angiography was used as reference standard, combined coronary CTA and CTP compared to coronary CTA alone significantly improved the specificity from 0.62 (95% CI: 0.52-0.70) to 0.84 (95% CI: 0.74-0.91) on a per-patient level (p = 0.008) and from 0.72 (95% CI: 0.63-0.79) to 0.90 (95% CI: 0.85-0.93) on a per-artery level (p = 0.0001) without significant decrease in sensitivity (p = 0.59 and p = 0.23, respectively). Conclusion: In selected patients, static CT myocardial perfusion has high diagnostic accuracy to detecting myocardial ischemia. Specificity increases significantly when CT myocardial perfusion is combined with coronary CFA.
- The role of cardiovascular magnetic resonance in takotsubo syndrome(2016) PLACIDO, Rui; LOPES, Bernardo Cunha; ALMEIDA, Ana G.; ROCHITTE, Carlos E.Takotsubo syndrome (TS) is a transient form of left ventricular dysfunction associated with a distinctive contraction pattern in the absence of significant coronary artery disease triggered by stressful events. Several aspects of its clinical profile have been described but it still remains difficult to quickly establish the diagnosis at admission. Cardiovascular magnetic resonance (CMR) has achieved great improvements in the last years, which in turn has made this imaging technology more attractive in the diagnosis and evaluation of TS. With its superior tissue resolution and dynamic imaging capabilities, CMR is currently the most useful imaging technique in this setting. In this review, we propose to comprehensively define the role of CMR in the evaluation of patients with TS and to summarize a set of criteria suitable for diagnostic decision making in this clinical setting.
- Deposit Diseases as Differential Diagnosis of Left Ventricular Hypertrophy in Patients with Heart Failure and Preserved Systolic Function(2019) FERNANDES, Fabio; ANTUNES, Murillo Oliveira; HOTTA, Viviane Tiemi; ROCHITTE, Carlos Eduardo; MADY, CharlesHeart failure with preserved systolic function is the main clinical manifestations of patients with ventricular hypertrophy. Conventional treatment is based on the improvement of diastolic dysfunction and congestion. However, no drug has been shown to be effective in the survival of these patients. Thus, it is important to look for the etiology of ventricular hypertrophy with the aim of a treatment directed to the underlying disease.
- The Top 10 Original Articles Published in the Arquivos Brasileiros de Cardiologia and in the Revista Portuguesa de Cardiologia in 2019(2020) OLIVEIRA, Glaucia Maria Moraes de; FONTES-CARVALHO, Ricardo; GONCALVES, Lino; CARDIM, Nuno; ROCHITTE, Carlos Eduardo
- The Year in Cardiology 2018: ABC Cardiol and RPC at a glance(2019) FONTES-CARVALHO, Ricardo; OLIVEIRA, Glaucia Maria Moraes de; GONCALVES, Lino; ROCHITTE, Carlos Eduardo
- 2021 Top 10 Articles in the Arquivos Brasileiros de Cardiologia and the Revista Portuguesa de Cardiologia(2022) FONTES-CARVALHO, Ricardo; OLIVEIRA, Glaucia Maria Moraes de; GONCALVES-TEIXEIRA, Pedro; ROCHITTE, Carlos Eduardo; CARDIM, Nuno
- Cardiovascular Magnetic Resonance for Patients With COVID-19(2022) PETERSEN, Steffen E.; FRIEDRICH, Matthias G.; LEINER, Tim; ELIAS, Matthew D.; FERREIRA, Vanessa M.; FENSKI, Maximilian; FLAMM, Scott D.; FOGEL, Mark; GARG, Ria; HALUSHKA, Marc K.; HAYS, Allison G.; KAWEL-BOEHM, Nadine; KRAMER, Christopher M.; NAGEL, Eike; NTUSI, Ntobeko A. B.; OSTENFELD, Ellen; PENNELL, Dudley J.; RAISI-ESTABRAGH, Zahra; REEDER, Scott B.; ROCHITTE, Carlos E.; STAREKOVA, Jitka; SUCHA, Dominika; TAO, Qian; SCHULZ-MENGER, Jeanette; BLUEMKE, David A.COVID-19 is associated with myocardial injury caused by ischemia, inflammation, or myocarditis. Cardiovascular magnetic resonance (CMR) is the noninvasive reference standard for cardiac function, structure, and tissue composition. CMR is a potentially valuable diagnostic tool in patients with COVID-19 presenting with myocardial injury and evidence of cardiac dysfunction. Although COVID-19-related myocarditis is likely infrequent, COVID-19-related cardiovascular histopathology findings have been reported in up to 48% of patients, raising the concern for long-term myocardial injury. Studies to date report CMR abnormalities in 26% to 60% of hospitalized patients who have recovered from COVID-19, including functional impairment, myocardial tissue abnormalities, late gadolinium enhancement, or pericardial abnormalities. In athletes post-COVID-19, CMR has detected myocarditis-like abnormalities. In children, multisystem inflammatory syndrome may occur 2 to 6 weeks after infection; associated myocarditis and coronary artery aneurysms are evaluable by CMR. At this time, our understanding of COVID-19-related cardiovascular involvement is incomplete, and multiple studies are planned to evaluate patients with COVID-19 using CMR. In this review, we summarize existing studies of CMR for patients with COVID-19 and present ongoing research. We also provide recommendations for clinical use of CMR for patients with acute symptoms or who are recovering from COVID-19. Crown
- Cardiovascular Imaging and Interventional Procedures in Patients with Novel Coronavirus Infection(2020) COSTA, Isabela Bispo Santos da Silva; ROCHITTE, Carlos Eduardo; CAMPOS, Carlos M.; BARBERATO, Silvio Henrique; OLIVEIRA, Glaucia Maria Moraes de; LOPES, Marcelo Antonio Cartaxo Queiroga; NOMURA, Cesar Higa; ABIZAID, Alexandre A.; CERRI, Giovanni; KALIL FILHO, Roberto; HAJJAR, Ludhmila AbrahaoThe coronavirus disease 2019 (COVID-19) pandemic is a huge challenge to the health system because of the exponential increase in the number of individuals affected. The rational use of resources and correct and judicious indication for imaging exams and interventional procedures are necessary, prioritizing patient, healthcare personnel, and environmental safety. This review was aimed at guiding health professionals in safely and effectively performing imaging exams and interventional procedures.