CARLOS EDUARDO ROCHITTE
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/64, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/64, Hospital das Clínicas, Faculdade de Medicina - Líder
18 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 18
- Radiologic-Electrocardiography Correlation in Wellens Syndrome(2021) FONSECA, Eduardo Kaiser Ururahy Nunes; HERINGER FILHO, Nevelton; MONTEMOR, Marcelo L.; AVILA, Luiz Francisco Rodrigues de; ROCHITTE, Carlos Eduardo
- Fulvio Pileggi: An Icon of Brazilian Cardiology(2021) LUZ, Protasio L. da; MADY, Charles; KALIL FILHO, Roberto; ROCHITTE, Carlos Eduardo
- Position Statement on Diagnosis and Treatment of Cardiac Amyloidosis-2021(2021) V, Marcus Simoes; FERNANDES, Fabio; MARCONDES-BRAGA, Fabiana G.; SCHEINBERG, Philip; CORREIA, Edileide de Barros; ROHDE, Luis Eduardo P.; BACAL, Fernando; ALVES, Silvia Marinho Martins; MANGINI, Sandrigo; BIOLO, Andreia; BECK-DA-SILVA, Luis; SZOR, Roberta Shcolnik; MARQUES JUNIOR, Wilson; OLIVEIRA, Acary Souza Bulle; CRUZ, Marcia Waddington; BUENO, Bruno Vaz Kerges; HAJJAR, Ludhmila Abrahao; ISSA, Aurora Felice Castro; RAMIRES, Felix Jose Alvarez; COELHO FILHO, Otavio Rizzi; SCHMIDT, Andre; PINTO, Ibraim Masciarelli Francisco; ROCHITTE, Carlos Eduardo; VIEIRA, Marcelo Luiz Campos; MESQUITA, Claudio Tinoco; RAMOS, Celso Dario; SOARES-JUNIOR, Jose; ROMANO, Minna Moreira Dias; MATHIAS JUNIOR, Wilson; GARCIA, Marcelo Iorio; MONTERA, Marcelo Westerlund; MELO, Marcelo Dantas Tavares de; SILVA, Sandra Marques E; GARIBALDI, Pedro Manoel Marques; ALENCAR, Aristoteles Comte de; LOPES, Renato Delascio; AVILA, Diane Xavier de; VIANA, Denizar; SARAIVA, Jose Francisco Kerr; CANESIN, Manoel Fernandes; OLIVEIRA, Glaucia Maria Moraes de; MESQUITA, Evandro Tinoco
- Natural History of Adapted Leaman Score Assessing Coronary Artery Disease Progression by Computed Tomography Angiography: A 7-Year Follow-Up Report(2021) HIDEO-KAJITA, Alexandre; GARCIA-GARCIA, Hector M.; RUBARTH, Rodrigo; WOPPERER, Samuel; OZAKI, Yuichi; FREIRE, Antonio Fernando Diniz; CAVALCANTE, Rafael; BITTENCOURT, Marcio; DAN, Kazuhiro; PINHEIRO, Thais L.; FALCAO, Breno A. A.; FALCAO, Joao Luis A.; SOARES, Paulo; RIBEIRO, Expedito; ROCHITTE, Carlos E.; LEMOS, Pedro AlvesBackground: Coronary computed tomographic angiography (CCTA) provides a non-invasive assessment of the coronary artery tree. Computed Tomography - adapted Leaman Score (CT-LeSc) has been shown to be an independent predictor of cardiac events in coronary artery disease (CAD) patients with a score greater than 5 (high). Purpose: To investigate the relationship between CT-LeSc and the progression of CAD and to provide vessel- and segment-level CAD qualification and quantification at baseline and 7-year follow-up. Methods: Patients with multivessel CAD and CCTA assessments at baseline and follow-up were included. The CT-LeSc analysis was performed in a paired fashion. The patient-level scores and the differences between each phase were assessed by 2 analysts in an independent core laboratory. Results: This study analyzed 248 coronary segments from 17 patients with a mean follow-up interval of 75 +/- 0.6 years. The mean CT-LeSc at baseline and follow-up were 14.6 +/- 42 and 16.9 +/- 15, respectively, with an absolute increase of 2.3 +/- 1.8. The mean cumulative increase of new lesions was 0.2 = 02 per year. Over time, 14.6% of the non-obstructive lesions became obstructive, and 15.0% of the non-calcified plaques became calcified. There were 29 new lesions found at follow-up, and out of these, 16 were obstructive and 19 were non-calcified. Conclusion: In patients at high risk for cardiac events, as determined by CT-LeSc, there was an increase in CT-LeSc, obstructive lesions, and calcified plaques over the 7-year follow-up period. Most of the new lesions were obstructive and non-calcified. This is the first report showing long-term serial imaging CCTA changes in a high-risk population.
conferenceObject Impact of left ventricular fibrosis and longitudinal systolic strain on outcomes in low gradient aortic stenosis(2021) FUKUI, M.; ANNABI, M. S.; ROSA, V. E. E.; RIBEIRO, H. B.; TARASOUTCHI, F.; SHELBERT, E. B.; BERGLER-KLEIN, J.; MASCHERBAUER, J.; ROCHITTE, C. E.; PIBAROT, P.; CAVALCANTE, J. L.- Position Statement on Indications and the Safe Reintroduction of Cardiovascular Imaging Methods in the COVID-19 Scenario-2021(2021) BECK, Adenalva Lima de Souza; BARBERATO, Silvio Henrique; ALMEIDA, Andre Luiz Cerqueira de; GRAU, Claudia R. Pinheiro de Castro; LOPES, Marly Maria Uellendahl; LIMA, Ronaldo de Souza Leao; CERCI, Rodrigo Julio; ALBRICKER, Ana Cristina Lopes; BARROS, Fanilda Souto; OLIVEIRA, Alessandra Joslin; LIRA, Edgar Bezerra de; MIGLIORANZA, Marcelo Haertel; VIEIRA, Marcelo Luiz Campos; PENA, Jose Luiz Barros; STRABELLI, Tania Mara Varejao; BIHAN, David Costa de Souza Le; TSUTSUI, Jeane Mike; ROCHITTE, Carlos Eduardo
- Brazilian Position Statement on the Use Of Multimodality Imaging in Cardio-Oncology-2021(2021) MELO, Marcelo Dantas Tavares de; PAIVA, Marcelo Goulart; SANTOS, Maria Veronica Camara; ROCHITTE, Carlos Eduardo; MOREIRA, Valeria de Melo; SALEH, Mohamed Hassan; BRANDAO, Simone Cristina Soares; GALLAFRIO, Claudia Cosentino; GOLDWASSER, Daniel; GRIPP, Eliza de Almeida; PIVETA, Rafael Bonafim; SILVA, Tonnison Oliveira; SANTO, Thais Harada Campos Espirito; FERREIRA, Waldinai Pereira; SALEMI, Vera Maria Cury; CAUDURO, Sanderson A.; BARBERATO, Silvio Henrique; LOPES, Heloisa M. Christovam; PENA, Jose Luiz Barros; RACHED, Heron Rhydan Saad; MIGLIORANZA, Marcelo Haertel; PINHEIRO, Aurelio Carvalho; VRANDECIC, Barbara Athayde Linhares Martins; CRUZ, Cecilia Beatriz Bittencourt Viana; NOMURA, Cesar Higa; CERBINO, Fernanda Mello Erthal; COSTA, Isabela Bispo Santos da Silva; COELHO FILHO, Otavio Rizzi; CARNEIRO, Adriano Camargo de Castro; BURGOS, Ursula Maria Moreira Costa; FERNANDES, Juliano Lara; UELLENDAHL, Marly; CALADO, Eveline Barros; SENRA, Tiago; ASSUNCAO, Bruna Leal; FREIRE, Claudia Maria Vilas; MARTINS, Cristiane Nunes; SAWAMURA, Karen Saori Shiraishi; BRITO, Marcio Miranda; JARDIM, Maria Fernanda Silva; BERNARDES, Renata Junqueira Moll; DIOGENES, Tereza Cristina; VIEIRA, Lucas de Oliveira; MESQUITA, Claudio Tinoco; LOPES, Rafael Willain; SEGUNDO NETO, Elry Medeiros Vieira; RIGO, Leticia; MARIN, Valeska Leite Siqueira; SANTOS, Marcelo Jose; GROSSMAN, Gabriel Blacher; QUAGLIATO, Priscila Cestari; ALCANTARA, Monica Luiza de; TEODORO, Jose Aldo Ribeiro; ALBRICKER, Ana Cristina Lopes; BARROS, Fanilda Souto; AMARAL, Salomon Israel do; PORTO, Carmen Lucia Lascasas; BARROS, Marcio Vinicius Lins; SANTOS, Simone Nascimento Dos; CANTISANO, Armando Luis; PETISCO, Ana Claudia Gomes Pereira; BARBOSA, Jose Eduardo Martins; VELOSO, Orlando Carlos Gloria; SPINA, Salvador; PIGNATELLI, Ricardo; HAJJAR, Ludhmilla Abrahao; KALIL FILHO, Roberto; LOPES, Marcelo Antonio Cartaxo Queiroga; VIEIRA, Marcelo Luiz Campos; ALMEIDA, Andre Luiz Cerqueira
conferenceObject Multimodality imaging and systemic biomarkers in classical low-flow low-gradient aortic stenosis: key findings for cardiac remodeling evaluation(2021) LOPES, M. A. A. A. M. L.; CAMPOS, C. M.; ROSA, V. E. E.; SAMPAIO, R. O.; MORAIS, T. C.; BRITO, F. S.; VIEIRA, M. L. C.; MATHIAS, W.; MEDEIROS, H. N. A. A.; SANTIS, A. S. A. L.; ROCHITTE, C. E.; RIBEIRO, M. H.; SANTOS, L. M.; ABIZAID, A.; TARASOUTCHI, F.- 2020 Top 10 Original Articles in the Arquivos Brasileiros de Cardiologia and the Revista Portuguesa de Cardiologia(2021) FONTES-CARVALHO, Ricardo; OLIVEIRA, Glaucia Maria Moraes de; CARDIM, Nuno; ROCHITTE, Carlos Eduardo
- Cooling as an Adjunctive Therapy to Percutaneous Intervention in Acute Myocardial Infarction: COOL-MI InCor Trial(2021) DALLAN, Luis Augusto Palma; GIANNETTI, Natali Schiavo; ROCHITTE, Carlos Eduardo; POLASTRI, Thatiane Facholi; MARTIN, Claudia Yanet Bernoche San; HAJJAR, Ludhmila Abrahao; NICOLAU, Jose Carlos; JR, Mucio Tavares de Oliveira; DAE, Michael; SILVA, Expedito Eustaquio Ribeiro da; KALIL FILHO, Roberto; LEMOS, Pedro Alves; TIMERMAN, SergioEndovascular Therapeutic hypothermia (ETH) reduces the damage caused by postischemia reperfusion injury syndrome in cardiopulmonary arrest and has already established its role in patients with sudden death; however, its role in ST-segment elevation myocardial infarction (STEMI) remains controversial. The objectives of this study were to investigate the safety, feasibility, and 30-day efficacy of rapid induction of therapeutic hypothermia as adjunctive therapy to percutaneous coronary intervention (PCI) in patients with anterior and inferior STEMIs. This was a prospective, controlled, randomized, two-arm, prospective, interventional study of patients admitted to the emergency department within 6 hours of angina onset, with anterior or inferior STEMI eligible for PCI. Subjects were randomized to the hypothermia group (primary PCI+ETH) or to the control group (primary PCI) at a 4:1 ratio. The ETH was induced by 1 L cold saline (1-4 degrees C) associated with the Proteus (TM) System, by cooling for at least 18 minutes before coronary reperfusion with a target temperature of 32 degrees C +/- 1 degrees C. Maintenance of ETH was conducted for 1-3 hours, and active reheating was done at a rate of 1 degrees C/h for 4 hours. Primary safety outcomes were the feasibility of ETH in the absence of (1) door-to-balloon (DTB) delay; (2) major adverse cardiac events (MACE) within 30 days after randomization. The primary outcomes of effectiveness were infarct size (IS) and left ventricular ejection fraction (LVEF) at 30 days. An as-treated statistical analysis was performed. Fifty patients were included: 35 (70%) randomized to the hypothermia group and 15 (30%) to the control group. The mean age was 58 +/- 12 years; 78% were men; and associated diseases were 60% hypertension, 42% diabetes, and 72% dyslipidemia. The compromised myocardial wall was anterior in 38% and inferior in 62%, and the culprit vessels were left anterior descending artery (LAD) (40%), right coronary artery (38%), and left circumflex (18%). All 35 patients who attempted ETH (100%) had successful cooling, with a mean endovascular coronary reperfusion temperature of 33.1 degrees C +/- 0.9 degrees C. The mean ischemic time was 375 +/- 89.4 minutes in the hypothermia group and 359.5 +/- 99.4 minutes in the control group. The mean DTB was 92.1 +/- 20.5 minutes in the hypothermia group and 87 +/- 24.4 minutes in the control group. The absolute difference of 5.1 minutes was not statistically significant (p = 0.509). The MACE rates were similar between both groups (21.7% vs. 20% respectively,p = 0.237). In the comparison between the hypothermia and control groups, no statistically significant differences were observed at 30 days between mean IS (13.9% +/- 8% vs. 13.8% +/- 10.8%, respectively,p = 0.801) and mean final LVEF (43.3% +/- 11.2% vs. 48.3 +/- 10.9%, respectively;p = 0.194). Hypothermia as an adjunctive therapy to primary PCI in STEMI is feasible and can be implemented without delay in coronary reperfusion. Hypothermia was safe regarding the incidence of MACE at 30 days. However, there was a higher incidence of arrhythmia and in-hospital infection in the hypothermia group, with no increase in mortality. Regarding efficacy, there was no difference in IS or LVEF at 30 days that would suggest additional myocardial protection with ETH.ClinicalTrials.gov:NCT02664194.