JOAO MARCOS SALGE
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- Does modified incremental step test evaluate maximal exercise capacity in moderate to severe subjects with asthma?(2019) BARBOSA, Renata; SILVA, Ronaldo; CAMARGO, Simone; CORSO, Simone Dal; SALGE, Joao Marcos; FONSECA, Alfredo Jose; STELMACH, Rafael; CARVALHO, Celso
conferenceObject Dynamic Hyperinflation and Exercise Performance in Non-Cystic Fibrosis Bronchiectasis: Clinical, Radiological and Functional Correlations(2019) MAIORANO, M. C.; FERNANDES, F. L. A.; SALGE, J. M.; STELMACH, R.; CUKIER, A.; ATHANAZIO, R. A.- Evaluation of lung function in patients submitted to total laryngectomy(2019) CASTRO, Mario A.; DEDIVITIS, Rogerio A.; SALGE, Joao M.; MATOS, Leandro L.; CERNEA, Claudio R.Introduction: The post-laryngectomy state is characterized by several alterations in lung function. A reliable estimation of lung function can be very useful in laryngectomees to prevent postoperative complications and to evaluate the results of the treatment. Objective: Characterize the presence of respiratory functional disorders and the functional pattern of laryngectomees through the use of an extratracheal device. Methods: This transversal study included 50 patients submitted to total laryngectomy at least 6 months prior to this investigation, as the treatment of choice for laryngeal cancer. Results: 56% percent of the participants had altered breathing pattern, distributed as follows: 14 with obstructive pattern with no air trapping, 11 with obstructive pattern with air trapping and only 3 with restrictive pattern. On average, the diffusion decreased (74.3%) and airway resistance increased (121.7%) when compared to the expected average values for the Brazilian individuals. Conclusion: Most patients submitted to total laryngectomy present altered lung function, usually the obstructive type, frequently associated to a history of smoking. (C) 2018 Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervico-Facial.
- Pulmonary Hypertension in Pulmonary Langerhans Cell Histiocytosis: prevalence and the role of Cardiopulmonary Exercise Testing and echocardiogram in predicting it(2019) HEIDEN, Glaucia Itamaro; SOBRAL, Juliana Barbosa; ALVES JR., Jose Leonidas; SALGE, Joao Marcos; ALBUQUERQUE, Andre Luis; FERNANDES, Caio Julio Cesar; KAIRALLA, Ronaldo; CARVALHO, Carlos Roberto Ribeiro; SOUZA, Rogerio; BALDI, Bruno Guedes
- Effects of weight loss on dynamic hyperinflation in obese women asthmatics(2019) SILVA, Aline Grandi; FREITAS, Patricia Duarte; FERREIRA, Palmira Gabriele; STELMACH, Rafael; CARVALHO-PINTO, Regina Maria; SALGE, Joao Marcos; MARTINS, Milton Arruda; CARVALHO, Celso R. F.Obese adults with asthma are more likely to develop dynamic hyperinflation (DH) and expiratory flow limitation (EFL) than nonobese asthmatics, and weight-loss seems to improve the breathing mechanics during exercise. However, studies evaluating the effect of weight loss on DH in obese adults with asthma have not been performed. We sought to evaluate the effect of a weight loss program on DH in obese adults with asthma. Forty-two asthma patients were enrolled in a weight loss program (diet, psychological support, and exercise) and were subsequently divided into two groups according to the percentage of weight loss: a >= 5% group (n = 19) and a <5% group (n = 23). Before and after the intervention. DH and EFL (constant load exercise), health-related quality of life (HRQoL). asthma control, quadriceps muscle strength and endurance, body composition, and lung function were assessed. Both groups exhibited a decrease of >= 10% in inspiratory capacity (DH) before intervention, and only the >= 5% group showed clinical improvement in DH compared with the <5% group postintervention (-9.1 +/- 14.5% vs. -125 +/- 13.5%, respectively). In addition, the >= 5% group displayed a significant delay in the onset of both DH and EH, and a clinically significant improvement in HRQoL and asthma control. Furthermore, a correlation was observed between reduced waist circumference and increased inspiratory capacity (r = -0.45, P = 0.05) in the >= 5% group. In conclusion, a weight-loss of >= 5% of the body weight improves DH, which is associated with waist circumference in obese adults with asthma. In addition, the group with greater weight-loss showed a delayed onset of DH and EFL during exercise and improved asthma clinical control and HRQoL. NEW & NOTEWORTHY This is the first study to evaluate dynamic hyperinflation (DH) after a weight loss program in obese patients with asthma. Our results demonstrate that moderate weight loss can improve DH in obese patients with asthma that is associated with a decrease in abdominal fat. Moreover, a minimum of 5% in weight loss delays the onset of DH and expiratory flow limitation besides inducing a clinical improvement in asthma quality of life and clinical control.