ANA CRISTINA SAYURI TANAKA
Índice h a partir de 2011
5
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
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conferenceObject RESTRICTIVE AND HYPERTROPHIC CARDIOMYOPATHIES AS INDICATION FOR HEART TRANSPLANTATION: CLINICAL OUTCOME IN A SINGLE CENTER(2013) TANAKA, Ana Cristina; MIURA, Nana; THOMAZ, Ana Maria; AIELLO, Vera Demarchi; BENEVENUTI, Luiz; TAVARES, Glaucia; NOMURA, Cesar; JATENE, Marcelo Biscegli; AZEKA, EstelaPURPOSE: The purpose of this study was evaluate the prevalence and outcome of restrictive and hypertrophic cardiomyopathies in a cohort of pediatric heart transplantation. METHOD: To evaluate the prevalence and clinical outcome of children with restrictive and hypertrophic cardiomyopathies submitted heart transplantation. RESULTS: From october 1992 to 2012, 115 patients were submitted heart transplantation. 120 transplants were performed at Heart Institute (InCor) University São Paulo Medical School. Seventeen (14,7%) of these patients hat restrictive cardiomyopathy/hypertrophic cardiomyopathy and have undergone to heart transplantation. The mean age was 10,4 years. Survival was 76,4%. Follow-up period ranged from 26 days to 6,6 years. CONCLUSION: Restrictive and hypertrophic cardiomyopathies can be an indication for heart transplantation a favorable outcome.- I DIRETRIZ DE INSUFICIÊNCIA CARDÍACA (IC) E TRANSPLANTE CARDÍACO, NO FETO, NA CRIANÇA E EM ADULTOS COM CARDIOPATIA CONGÊNITA, DA SOCIEDADE BRASILEIRA DE CARDIOLOGIA(2014) AZEKA, E.; JATENE, M. B.; JATENE, I. B.; HOROWITZ, E. S. K.; BRANCO, K. C.; SOUZA NETO, J. D.; MIURA, N.; MATTOS, S.; AFIUNE, J. Y.; TANAKA, A. C.; SANTOS, C. C. L.; GUIMARAES, I. C. B.; MANSO, P. H.; PELLIZARI, R. C. R. S.; SANTOS, M. V. C.; THOMAZ, A. M.; CRISTOFANI, L. M.; RIBEIRO, A. C. L.; KULIKOWSKI, L. D.; SAMPAIO, M. C.; PEREIRA, A. C.; SOARES, A. M.; SOARES JUNIOR, J.; OH, G. H. Y.; MOREIRA, V; MOTA, C. C. C.; AFIUNE, C. M. C.; PEDRA, C.; PEDRA, S.; PEDROSA, A.; GUIMARAES, V; CANEO, L. F.; FERREIRO, C. R.; CAVALHEIRO FILHO, C.; STEFANELLO, B.; NEGRAO, C. E.; TURQUETTO, A. L. R.; MESQUITA, S. M. F.; MAEDA, W. T.; ZORZANELLI, L.; PANAJOTOPOLOS, N.; SIQUEIRA, A. W. S.; GALAS, F. R. B.; HAJJAR, L. A.; BENVENUTI, L. A.; VINCENZI, P.; ODONE, V; LOPES, M. H.; V, T. M. Strabelli; FRANCHI, S. M.; TAKEUTI, A. D.; DUARTE, M. F.; LEON, R. G. P.; HERMIDA, R. P. M.; SORPRESO, I. C. E.; SOARES JUNIOR, J. M.; MELO, N. R.; BARACAT, E. C.; BORTOLOTTO, M. R. F. L.; SCANAVACCA, M.; SHIMODA, M. S.; FORONDA, G.; ROMANO, B. W.; SILVA, D. B.; OMURA, M. M.; BARBEIRO, C. P. M.; VINHOLE, A. R. G.; PALOMO, J. S. H.; GONCALVES, M. A. B.; REIS, I. C. F.; OLIVEIRA, L. G.; RIBEIRO, C. C.; ISOSAKI, M.; VIEIRA, L. P.; FELTRIM, M. I. Z.; MANOEL, L. A.; ABUD, K. C. O.; PASCHOTTO, D. R.; NEVES, I. L. I.; SENAHA, L. E.; GARCIA, A. C. C. N.; CIPRIANO, S. L.; SANTOS, V. C.; FERRAZ, A. S.; MOREIRA, A. E. L. C.; PAULO, A. R. S. A. De; DUQUE, A. M. P. C.; TRINDADE, E.; BACAL, F.; AULER JUNIOR, J. O. C.; ALMEIDA, D. R.
conferenceObject SIBLINGS WITH RESTRICTIVE SYNDROME AND HYPERTROPHIC CARDIOMYOPATHY: A RARE CASE OF SUCCESSFUL HEART TRANSPLANTATION(2013) AZEKA, Estela; KAWASAKA, Ana Laura B. C.; TANAKA, Ana Cristina S.; PEREIRA, Alexandre C.; AIELLO, Vera D.; JATENE, Marcelo B.PURPOSE: To report the cases of siblings with restrictive syndrome who underwent heart transplantation and whose hearts had histological characteristics of hypertrophic cardiomyopathy (HCM). METHOD: Case1) A 7 year-old boy with recurrent pneumonias and cardiomegaly. Echocardiography showed features of restrictive cardiomyopathy. No pericardial commitment was found. Due to refractory congestive heart failure he was listed and successfully transplanted at the age 14. The analysis of the explanted heart revealed diffuse myocite disarray, with no septal asymmetry or subaortic obstruction. He is currently in clinical follow up for 5 years. Case 2) A 10 year-old female with exertion dyspnea, cyanosis and vomits. Due to the family history, she was referred for investigation. Restrictive cardiomyopathy was diagnosed. She was listed for heart transplant and successfully transplanted at the age of 13. The analysis of the explanted heart showed mild thickening of ventricular walls with no asymmetries or subaortic obstruction and several areas of myocyte disarray and fibrosis. She is currently in clinical follow up for 2 years. Blood samples of our patients were tested for mutations in genes MYH7, MYBPC and Troponin I (most frequently related to HCM in Brazil), but no alterations were found. CONCLUSION: HCM is a genetic condition related to mutations in genes that encode components of the sarcomere. It can rarely present with features of restrictive syndrome. Heart transplant is the therapeutic option for refractory congestive heart failure, before the evolution to pulmonary hypertension, with good clinical outcome.- Heart Transplantation in Children and Adults With Congenital Heart Disease: 3 Decades of Evolution(2023) AZEKA, Estela; SIQUEIRA, Adailson Wagner Da Silva; TANAKA, Ana Cristina; MASSOTI, Maria Raquel Brigoni; MIANA, Leonardo; ZORZANELLI, Leina; GUIMARAES, Vanessa; PENHA, Juliano; CANEO, Luiz Fernando; TANAMATI, Carla; MIURA, Nana; JATENE, Marcelo BiscegliHeart transplantation is the treatment of choice for children and adults with congenital heart disease. We report the heart transplant single-center experience. The number of transplantations has increased over the last 3 decades. The Kaplan-Meier survival curves in the first, second, and third decades at 5 and 10 years were 69% and 59%, 62% and 52%, and 66% and 60%, respectively.
- RESTRICTIVE SYNDROME AND HYPERTROPHIC CARDIOMIOPATHY AS INDICATION FOR HEART TRANSPLANTATION: CLINICAL OUTCOME IN A SINGLE CENTER(2013) TANAKA, Ana Cristina; MIURA, Nana; THOMAZ, Ana Maria; FERNANDES, Marcos; VALE, Natalia Freitas de Deus; AIELLO, Vera; BENVENUTI, Luiz; TAVARES, Glaucia; NOMURA, Cesar; JATENE, Marcelo; AZEKA, EstelaOBJECTIVES: The purpose of this study was to evaluate the prevalence and outcome of restrictive syndrome in a cohort of pediatric heart transplantation. MATERIAL AND METHODS: To evaluate the prevalence and clinical outcome of children with restrictive syndrome and hypertrophic cardiomiopathy submitted to heart transplantation. RESULTS: From October 1992 to 2012, 115 patients were submitted to heart transplantation. One hundred and twenty transplants were performed at Heart Institute (InCor) University of Sao Paulo Medical School. Seventeen (14.7%) of these patients had restrictive syndrome and have undergone to heart transplantation. The mean age was 10.4 yrs. Survival was 76.4%. Follow up period ranged from 26 days to 6.6 yrs. CONCLUSION: Restrictive syndrome and hypertrophic cardiomyopathy can be an indication for heart transplantation with a favorable outcome.
- Clinical recommendations for postoperative care after heart transplantation in children: 21 years of a single-center experience(2014) AZEKA, Estela; JATENE, Marcelo Biscegli; TANAKA, Ana Cristina; GALAS, Filomena Regina; HAJJAR, Ludhmilla Abrahao; MIURA, Nana; AULER JUNIOR, Jose Otavio CostaHeart transplantation is an option for children with complex congenital heart disease and cardiomyopathies. A patient's quality of life and long-term survival depend on successful management of the surgical complications and adverse side effects of immunosuppression. The purpose of this review was to summarize the practical management of postoperative care in this patient population and to make recommendations for the future.