MARIA CAROLINA FERES DE ALMEIDA SOEIRO
Índice h a partir de 2011
7
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
10 resultados
Resultados de Busca
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bookPart Ecocardiograma na emergência(2018) SOEIRO, Maria Carolina Feres de Almeida; HOTTA, Viviane Tiemi; VIEIRA, Marcelo Luiz Campos; JúNIOR, Wilson Mathias- High tumour burden, delayed diagnosis and history of cardiovascular disease may be associated with carcinoid heart disease(2018) ALVES, Carolina; MESQUITA, Marcella; SILVA, Carolina; SOEIRO, Maria; HAJJAR, Ludhmila; RIECHELMANN, Rachel P.Background: Patients with carcinoid syndrome (CS) may present carcinoid heart disease (CHD) but prognostic factors are not entirely understood. Patients and Methods: Retrospective study of patients with metastatic neuroendocrine tumours (NETs) and CS and/or abnormal 24-hour-urinary 5-hydroxiindolacetic acid. CHD was defined as moderate to severe tricuspid or pulmonary regurgitation in the echocardiogram. Results: The frequency of CHD among 42 patients was 38% (95% confidence interval [CI]: 23%-54%). CHD was associated with higher volume of liver metastases (odds ratio [OR] 13.86, 95% CI: 2.57-74.68, p = 0.002). Time from CS symptoms to NET diagnosis was borderline significant (p = 0.08). When CHD was defined as at least mild tricuspide regurgitation, the frequency of CHD was 45% and it was associated with cardiovascular comorbidities (OR: 6.58, 95% CI: 1.09; 39.78, p = 0.040). Conclusion: CHD was frequent among patients with CS, significantly associated with high liver tumour burden, and likely linked to the history of cardiovascular disease and longer time of CS.
bookPart Síndrome coronária aguda em pacientes diabéticos(2018) SOEIRO, Alexandre de Matos; SOEIRO, Maria Carolina Feres de Almeida; JúNIOR, Múcio Tavares de Oliveira; HAJJAR, Ludhmila Abrahão- Is There Any Relationship between TSH Levels and Prognosis in Acute Coronary Syndrome?(2018) SOEIRO, Alexandre de Matos; ARAUJO, Victor Arrais; VELLA, Julia Pitombo; BOSSA, Aline Siqueira; BISELLI, Bruno; LEAL, Tatiana de Carvalho Andreucci Torres; SOEIRO, Maria Carolina Feres de Almeida; SERRANO JR., Carlos V.; MUELLER, Christian; OLIVEIRA JUNIOR, Mucio Tavares deBackground: Some small studies have related higher levels of thyrotropin (TSH) to potentially worse prognosis in acute coronary syndromes. However, this relationship remains uncertain. Objective: To analyze the outcomes of patients with acute coronary syndromes in relation to the value of TSH at admission. Methods: Observational and retrospective study with 505 patients (446 in group I [TSH <= 4 mIU/L] and 59 in group II [TSH > 4 mIU/L]) with acute coronary syndromes between May 2010 and May 2014. We obtained data about comorbidities and the medications used at the hospital. The primary endpoint was in-hospital all-cause death. The secondary endpoint included combined events (death, non-fatal unstable angina or myocardial infarction, cardiogenic shock, bleeding and stroke). Comparisons between groups were made by one-way ANOVA and chi-square test. Multivariate analysis was determined by logistic regression. Analyses were considered significant when p < 0.05. Results: Significant differences between groups I and II were observed regarding the use of enoxaparin (75.2% vs. 57.63%, p = 0.02) and statins (84.08% vs. 71.19%, p < 0.0001), previous stroke (5.83% vs. 15.25%, p = 0.007), combined events (14.80% vs. 27.12%, OR = 3.05, p = 0.004), cardiogenic shock (4.77% vs. 6.05%, OR = 4.77, p = 0.02) and bleeding (12.09% vs. 15.25%, OR = 3.36, p = 0.012). Conclusions: In patients with acute coronary syndromes and TSH > 4 mIU/L at admission, worse prognosis was observed, with higher incidences of in-hospital combined events, cardiogenic shock and bleeding.
bookPart Síndrome coronária aguda em pacientes diabéticos(2018) SOEIRO, Alexandre de Matos; SOEIRO, Maria Carolina Feres de Almeida; OLIVEIRA JR., Múcio Tavares de; HAJJAR, Ludhmila Abrahão- CardioER (R) - Using smartphone medical applications as an aid to clinical decision-making - are we ready for this?(2018) SOEIRO, Alexandre de Matos; LEAL, Tatiana de Carvalho Andreucci Torres; BOSSA, Aline Siqueira; SOEIRO, Maria Carolina Feres de Almeida; SERRANO JR., Carlos Vicente; OLIVEIRA JR., Mucio Tavares
conferenceObject High Hepatic Tumor Burden and History of Cardiovascular Comorbidities Are Associated with Carcinoid Heart Disease: A Multicenter and Multinational Study(2018) RIECHELMANN, R.; MESQUITA, M.; ALVES, C.; SILVA, C.; SOEIRO, M.; LUCA, R.; ANGEL, M.; CONNOR, J. M. O'- Prognostic Differences between Men and Women with Acute Coronary Syndrome. Data from a Brazilian Registry(2018) SOEIRO, Alexandre de Matos; SILVA, Pedro Gabriel Melo de Barros e; ROQUE, Eduardo Alberto de Castro; BOSSA, Aline Siqueira; BISELLI, Bruno; LEAL, Tatiana de Carvalho Andreucci Torres; SOEIRO, Maria Carolina Feres de Almeida; PITTA, Fabio Grunspun; V, Carlos Serrano Jr; JR, Mucio Tavares OliveiraBackground: Gender-related differences have been reported in patients with acute coronary syndrome. The description of this comparative finding in a Brazilian registry has not yet been documented. Objective: To compare male vs. female patients regarding the baseline characteristics, coronary findings, treatment and in-hospital and long-term prognosis. Methods: This is a retrospective, multicenter and observational study that included 3,745 patients (2,437 males and 1,308 females) between May 2010 and May 2015. The primary in-hospital outcome was all-cause mortality. The secondary outcome consisted of combined events (cardiogenic shock, reinfarction, death, stroke and bleeding). The comparison between groups was performed using the chi-square and the t test, considering p < 0.05 as significant. In the long term, mortality and combined events were assessed using the Kaplan-Meier method, with a mean follow-up of 8.79 months. Results: The mean age was 60.3 years for males and 64.6 for females (p < 0.0001). The most prevalent risk factor was systemic arterial hypertension in 72.9% of the women and 67.8% of the men (p = 0.001). Percutaneous coronary intervention was carried out in 44.9% of the males and 35.4% of the females (p < 0.0001), and coronary artery bypass grafting (CABG) was performed in 17% of the males and 11.8% of females (p < 0.0001), with a higher prevalence of three-vessel coronary artery disease in males (27.3% vs. 16.2%, p < 0.0001). Approximately 79.9% of the female patients received a diagnosis of acute coronary syndrome without ST-segment elevation, while in the male patients, this diagnosis was attained in 71.5% (p < 0.0001). No significant differences were observed between the groups in the short and long term, regarding both mortality and the combined events. Conclusion: Several gender-related differences were observed in patients with acute coronary syndrome regarding the demographic characteristics, coronary artery disease pattern and implemented treatment. However, the prognostic evolution was similar between the groups.
bookPart Ecocardiograma na emergência(2018) SOEIRO, Maria Carolina Feres de Almeida; HOTTA, Viviane Tiemi; VIEIRA, Marcelo Luiz Campos; MATHIAS JR., Wilson- Sensitive Troponin I Assay in Patients with Chest Pain - Association with Significant Coronary Lesions with or Without Renal Failure(2018) SOEIRO, Alexandre de Matos; GUALANDRO, Danielle Menosi; BOSSA, Aline Siqueira; ZULLINO, Cindel Nogueira; BISELLI, Bruno; SOEIRO, Maria Carolina Feres de Almeida; LEAL, Tatiana de Carvalho Andreucci Torres; SERRANO JR., Carlos Vicente; OLIVEIRA JUNIOR, Mucio Tavares deIntroduction: Despite having higher sensitivity as compared to conventional troponins, sensitive troponins have lower specificity, mainly in patients with renal failure. Objective: Study aimed at assessing the sensitive troponin I levels in patients with chest pain, and relating them to the existence of significant coronary lesions. Methods: Retrospective, single-center, observational. This study included 991 patients divided into two groups: with (N = 681) and without (N = 310) significant coronary lesion. For posterior analysis, the patients were divided into two other groups: with (N = 184) and without (N = 807) chronic renal failure. The commercial ADVIA Centaur (R) TnI-Ultra assay (Siemens Healthcare Diagnostics) was used. The ROC curve analysis was performed to identify the sensitivity and specificity of the best cutoff point of troponin as a discriminator of the probability of significant coronary lesion. The associations were considered significant when p < 0.05. Results: The median age was 63 years, and 52% of the patients were of the male sex. The area under the ROC curve between the troponin levels and significant coronary lesions was 0.685 (95% CI: 0.65 -0.72). In patients with or without renal failure, the areas under the ROC curve were 0.703 (95% CI: 0.66 - 0.74) and 0.608 (95% CI: 0.52 - 0.70), respectively. The best cutoff points to discriminate the presence of significant coronary lesion were: in the general population, 0.605 ng/dL (sensitivity, 63.4%; specificity, 67%); in patients without renal failure, 0.605 ng/dL (sensitivity, 62.7%; specificity, 71%); and in patients with chronic renal failure, 0.515 ng/dL (sensitivity, 80.6%; specificity, 42%). Conclusion: In patients with chest pain, sensitive troponin I showed a good correlation with significant coronary lesions when its level was greater than 0.605 ng/dL. In patients with chronic renal failure, a significant decrease in specificity was observed in the correlation of troponin levels and severe coronary lesions.