LIVER TRANSPLANTATION IN CHILDREN: 14 YEARS OF EXPERIENCE WITH LIVING DONORS

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorANDRADE, Wagner de Castro
dc.contributor.authorVELHOTE, Manoel Carlos Prieto
dc.contributor.authorAYOUB, Ali Abdul Rahman
dc.contributor.authorSILVA, Marcos Marques da
dc.contributor.authorGIBELLI, Nelson Elias Mendes
dc.contributor.authorPINHO-APEZZATO, Maria Lucia de
dc.contributor.authorTANNURI, Ana Cristina Aoun
dc.contributor.authorBARROS, Fabio de
dc.contributor.authorRICARDI, Luis Roberto Schlaich
dc.contributor.authorMOREIRA, Daniel de Albuquerque Rangel
dc.contributor.authorMIYATANI, Helena Thie
dc.contributor.authorPEREIRA, Paulo Renato Alencar
dc.contributor.authorTANNURI, Uenis
dc.date.accessioned2013-10-11T21:15:09Z
dc.date.available2013-10-11T21:15:09Z
dc.date.issued2013
dc.description.abstractOBJECTIVES: Report on the experience with 170 living donors in pediatric liver transplantation. MATERIAL AND METHODS: Retrospective analysis of the medical records of donors operated between June 1998 and October 2012. RESULTS: Over the past 14 yrs, 169 liver transplants were performed in pediatric recipients of living donor grafts. In a potential left lateral segment donor, there was a minor injury in the right branch of portal vein, repaired without consequences for the patient, but resulting in abortion of the transplant. From the remaining donors, 151 left lateral segments (89.34%), 17 left lobes (10.06%) and 1 right lobe (0.6%) were removed. Donor age ranged from 16 to 53 yrs and weight ranged from 47 to 106 kg. Transfusion of blood products was required in 14 donors (8.3%). The mean hospital stay was 5 days. Complications were identified in 21 patients (12.4%): 11 showed intense dyspeptic symptoms and abdominal pain (two patients underwent reoperation), seven presented minor bile leaks, and three developed extra-peritoneal infection (incision abscess, phlebitis and pneumonia). There was no mortality in this series. Eight grafts (4.7%) had primary dysfunction, resulting in death of the recipient (three cases of fulminant hepatitis, one metabolic disease carrier, one Alagille Syndrome carrier and three cases of biliary atresia in infants under 1 yr of age). CONCLUSION: Living-related liver transplantation in children generates low risk and morbidity for the donors of left lobe or left lateral segment grafts, with good outcomes for the recipients, eliminating the disadvantages of the waiting list for cadaveric grafts.
dc.description.conferencedateNOV 08-09, 2012
dc.description.conferencelocalSao Paulo, BRAZIL
dc.description.conferencename1st Brazilian Symposium of Pediatric Transplantation
dc.description.indexMEDLINE
dc.identifier.citationPEDIATRIC TRANSPLANTATION, v.17, n.2, p.194-194, 2013
dc.identifier.doi10.1111/petr.12037
dc.identifier.issn1397-3142
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/2648
dc.language.isoeng
dc.publisherWILEY-BLACKWELL
dc.relation.ispartofPediatric Transplantation
dc.rightsrestrictedAccess
dc.rights.holderCopyright WILEY-BLACKWELL
dc.subject.wosPediatrics
dc.subject.wosTransplantation
dc.titleLIVER TRANSPLANTATION IN CHILDREN: 14 YEARS OF EXPERIENCE WITH LIVING DONORS
dc.typeconferenceObject
dc.type.categorymeeting abstract
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalRICARDI, Luis Roberto Schlaich:Univ Sao Paulo, Fac Med, Pediat Surg & Liver Transplantat Div, Dept Pediat,Hosp Clin,Inst Criancca, Sao Paulo, Brazil
hcfmusp.contributor.author-fmusphcWAGNER DE CASTRO ANDRADE
hcfmusp.contributor.author-fmusphcMANOEL CARLOS PRIETO VELHOTE
hcfmusp.contributor.author-fmusphcALI ABDUL RAHMAN AYOUB
hcfmusp.contributor.author-fmusphcMARCOS MARQUES DA SILVA
hcfmusp.contributor.author-fmusphcNELSON ELIAS MENDES GIBELLI
hcfmusp.contributor.author-fmusphcMARIA LUCIA DE PINHO APEZZATO
hcfmusp.contributor.author-fmusphcANA CRISTINA AOUN TANNURI
hcfmusp.contributor.author-fmusphcFABIO DE BARROS
hcfmusp.contributor.author-fmusphcDANIEL DE ALBUQUERQUE RANGEL MOREIRA
hcfmusp.contributor.author-fmusphcHELENA THIE MIYATANI
hcfmusp.contributor.author-fmusphcPAULO RENATO DE ALENCAR PEREIRA
hcfmusp.contributor.author-fmusphcUENIS TANNURI
hcfmusp.description.beginpage194
hcfmusp.description.endpage194
hcfmusp.description.issue2
hcfmusp.description.volume17
hcfmusp.origemWOS
hcfmusp.origem.wosWOS:000315467000032
hcfmusp.publisher.cityHOBOKEN
hcfmusp.publisher.countryUSA
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Comunicações em Eventos - FM/MCG
Comunicações em Eventos - FM/MPE
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Comunicações em Eventos - LIM/26
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