Immune complexes as a tool for strongyloidiasis immunodiagnosis in kidney and liver transplant candidate

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCORRAL, Marcelo A.
dc.contributor.authorGONCALVES, Ana Lucia R.
dc.contributor.authorCOSTA, Idessania N.
dc.contributor.authorABDALA, Edson
dc.contributor.authorPIERROTTI, Ligia C.
dc.contributor.authorCHIEFFI, Pedro Paulo
dc.contributor.authorCOSTA-CRUZ, Julia Maria
dc.contributor.authorGRYSCHEK, Ronaldo Cesar B.
dc.contributor.authorPAULA, Fabiana Martins
dc.date.accessioned2022-08-12T17:07:49Z
dc.date.available2022-08-12T17:07:49Z
dc.date.issued2022
dc.description.abstractStrongyloidiasis is a chronic and asymptomatic infection in immunocompetent patients. Immunocompromised patients, such as organ transplant candidates, can develop severe forms of this disease, and the best way to prevent progression to these forms is early diagnosis. Serological techniques using specific IgG and immune complexes (IC) detection can help in the diagnosis of these patients. This study aimed to detect specific anti-Strongyloides IC and IgG antibodies in kidney transplant (KT) and liver transplant (LT) candidates. A total of 100 blood samples was collected from transplant candidates (50 blood samples each from KT and LT candidates). Serum was obtained and analysed using enzyme-linked immunosorbent assay for IC and IgG detections. The IC levels showed frequencies of 18% and 2% in the KT and LT groups, respectively, whereas anti-Strongyloides IgG was detected in 34% and 12% of KT and LT candidates, respectively. The correlation between IC and IgG detection is poor in KT candidates, while in LT candidates, there is a significant positive correlation. The detection of IC can be an additional tool for the diagnosis of strongyloidiasis, especially when associated with the detection of specific IgG anti-Strongyloides antibodies.eng
dc.description.indexMEDLINEeng
dc.description.sponsorshipFundac~ao de Amparo a Pesquisa do Estado de S~ao Paulo [FAPESP 2010/51110-0]
dc.identifier.citationPARASITE IMMUNOLOGY, v.44, n.7, article ID e12920, 5p, 2022
dc.identifier.doi10.1111/pim.12920
dc.identifier.eissn1365-3024
dc.identifier.issn0141-9838
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/48443
dc.language.isoeng
dc.publisherWILEYeng
dc.relation.ispartofParasite Immunology
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright WILEYeng
dc.subjecthuman strongyloidiasiseng
dc.subjectimmune complexeseng
dc.subjectimmunodiagnosticeng
dc.subjecttransplant candidateseng
dc.subject.otherdiagnosiseng
dc.subject.othervenezuelensiseng
dc.subject.wosImmunologyeng
dc.subject.wosParasitologyeng
dc.titleImmune complexes as a tool for strongyloidiasis immunodiagnosis in kidney and liver transplant candidateeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalGONCALVES, Ana Lucia R.:Univ Fed Uberlandia, Lab Diagnost Parasitoses, Uberlandia, MG, Brazil
hcfmusp.author.externalCOSTA, Idessania N.:Univ Estadual Londrina, Dept Ciencias Patol, Lab Imunoparasitol Doencas Negligenciadas & Canc, Londrina, Parana, Brazil
hcfmusp.author.externalCHIEFFI, Pedro Paulo:Fac Ciencias Med Santa Casa Sao Paulo, Sao Paulo, SP, Brazil
hcfmusp.author.externalCOSTA-CRUZ, Julia Maria:Univ Fed Uberlandia, Lab Diagnost Parasitoses, Uberlandia, MG, Brazil
hcfmusp.citation.scopus0
hcfmusp.contributor.author-fmusphcMARCELO ANDREETTA CORRAL
hcfmusp.contributor.author-fmusphcEDSON ABDALA
hcfmusp.contributor.author-fmusphcLIGIA CAMERA PIERROTTI
hcfmusp.contributor.author-fmusphcRONALDO CESAR BORGES GRYSCHEK
hcfmusp.contributor.author-fmusphcFABIANA MARTINS DE PAULA
hcfmusp.description.articlenumbere12920
hcfmusp.description.issue7
hcfmusp.description.volume44
hcfmusp.origemWOS
hcfmusp.origem.pubmed35430739
hcfmusp.origem.scopus2-s2.0-85129605459
hcfmusp.origem.wosWOS:000792215200001
hcfmusp.publisher.cityHOBOKENeng
hcfmusp.publisher.countryUSAeng
hcfmusp.relation.referenceAbanyie FA, 2018, TRANSPL INFECT DIS, V20, DOI 10.1111/tid.12865eng
hcfmusp.relation.referenceBatista MV, 2011, TROP MED INT HEALTH, V16, P1134, DOI 10.1111/j.1365-3156.2011.02816.xeng
hcfmusp.relation.referenceBoggild A K, 2016, Can Commun Dis Rep, V42, P12eng
hcfmusp.relation.referenceBosqui LR, 2018, PARASITOLOGY, V145, P1090, DOI 10.1017/S0031182017002232eng
hcfmusp.relation.referenceBosqui LR, 2021, PARASITE IMMUNOL, V43, DOI 10.1111/pim.12793eng
hcfmusp.relation.referenceBuonfrate D, 2020, PATHOGENS, V9, DOI 10.3390/pathogens9060468eng
hcfmusp.relation.referenceCorral MA, 2019, ACTA TROP, V190, P357, DOI 10.1016/j.actatropica.2018.12.020eng
hcfmusp.relation.referenceCorral MA, 2015, REV INST MED TROP SP, V57, P77, DOI 10.1590/S0036-46652015000100011eng
hcfmusp.relation.referencede Carvalho CA, 2013, ACTA TROP, V125, P128, DOI 10.1016/j.actatropica.2012.10.010eng
hcfmusp.relation.referencede Paula FM, 2016, REV INST MED TROP SP, V58, DOI 10.1590/S1678-9946201658063eng
hcfmusp.relation.referencede Paula FM, 2013, REV INST MED TROP SP, V55, P291, DOI 10.1590/S0036-46652013000400013eng
hcfmusp.relation.referenceEslahi AV, 2021, PATHOG GLOB HEALTH, V115, P7, DOI 10.1080/20477724.2020.1851922eng
hcfmusp.relation.referenceFrank Michael M., 2009, P79, DOI 10.1007/978-4-431-88315-9_6eng
hcfmusp.relation.referenceGarcia LS., 2001, DIAGNOSTIC MED PARAS, V4theng
hcfmusp.relation.referenceGoncalves ALR, 2016, J HELMINTHOL, V90, P342, DOI 10.1017/S0022149X15000346eng
hcfmusp.relation.referenceGoncalves ALR, 2012, PARASITOLOGY, V139, P956, DOI 10.1017/S0031182012000054eng
hcfmusp.relation.referenceGoncalves AAS, 2018, PARASITOL INT, V67, P644, DOI 10.1016/j.parint.2018.06.007eng
hcfmusp.relation.referenceGoncalves ALR, 2012, EXP PARASITOL, V130, P205, DOI 10.1016/j.exppara.2012.01.007eng
hcfmusp.relation.referenceLevenhagen MA, 2014, ACTA TROP, V135, P33, DOI 10.1016/j.actatropica.2014.03.015eng
hcfmusp.relation.referenceLOWRY OH, 1951, J BIOL CHEM, V193, P265eng
hcfmusp.relation.referenceMachado ER, 2003, MEM I OSWALDO CRUZ, V98, P849, DOI 10.1590/S0074-02762003000600024eng
hcfmusp.relation.referenceMendonca SCL, 2006, ACTA TROP, V99, P102, DOI 10.1016/j.actatropica.2006.06.006eng
hcfmusp.relation.referenceMiglioli-Galvao L, 2020, PLOS NEGLECT TROP D, V14, DOI 10.1371/journal.pntd.0007998eng
hcfmusp.relation.referenceMiguel CB, 2020, DIS MARKERS, V2020, DOI 10.1155/2020/4086929eng
hcfmusp.relation.referenceOlsen A, 2009, T ROY SOC TROP MED H, V103, P967, DOI 10.1016/j.trstmh.2009.02.013eng
hcfmusp.relation.referenceRoxby AC, 2009, CLIN INFECT DIS, V49, P1411, DOI 10.1086/630201eng
hcfmusp.relation.referenceSchar F, 2013, PLOS NEGLECT TROP D, V7, DOI 10.1371/journal.pntd.0002288eng
hcfmusp.relation.referenceSekhawat V, 2020, HISTOPATHOLOGY, V77, P156, DOI 10.1111/his.14111eng
hcfmusp.relation.referenceTeixeira MCA, 2016, BIOMED RES INT, V2016, DOI 10.1155/2016/4872473eng
hcfmusp.relation.referenceToledo B, 2019, CLINICS, V74, DOI 10.6061/clinics/2019/e698eng
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublication7ab579f4-aa79-49bb-8139-b4645a1e7dd9
relation.isAuthorOfPublication8f2a0908-530e-4109-9a31-d275670247f7
relation.isAuthorOfPublicationedd4167d-0bc8-4227-a85a-577e4a8c6d04
relation.isAuthorOfPublication7ec8d577-b8db-4d87-b541-6def85d667e6
relation.isAuthorOfPublication5d56e1dd-5ba9-4f59-bce7-1fcdf19f3114
relation.isAuthorOfPublication.latestForDiscovery7ab579f4-aa79-49bb-8139-b4645a1e7dd9
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
art_CORRAL_Immune_complexes_as_a_tool_for_strongyloidiasis_immunodiagnosis_2022.PDF
Tamanho:
1.1 MB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - FM/MIP
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - IMT
Artigos e Materiais de Revistas Científicas - LIM/47