Esophagojejunal anastomotic fistula: a major issue after radical total gastrectomy

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorBARCHI, Leandro Cardoso
dc.contributor.authorRAMOS, Marcus Fernando Kodama Pertille
dc.contributor.authorPEREIRA, Marina Alessandra
dc.contributor.authorDIAS, Andre Roncon
dc.contributor.authorRIBEIRO-JUNIOR, Ulysses
dc.contributor.authorZILBERSTEIN, Bruno
dc.contributor.authorCECCONELLO, Ivan
dc.date.accessioned2019-09-23T14:18:07Z
dc.date.available2019-09-23T14:18:07Z
dc.date.issued2019
dc.description.abstractGastric cancer surgery has evolved considerably over the past years, with substantial improvement on outcomes. Meanwhile, esophagojejunal anastomotic fistula (EJF) continues to impair postoperative results. This study aimed to assess EJF regarding its incidence, risk factors, management and the impact on overall survival. We retrospectively analyzed 258 consecutive patients who underwent total or completion gastrectomy for GC from 2009 and 2017. Clinicopathological characteristics analysis was performed comparing patients who developed EJF with patients with other clinical or surgical complications, as well as patients without any postoperative complications. Fifteen (5.8%) patients had EJF and 81 (31.4%) had other complications (including other surgical fistulas). The median time of EJF diagnosis was on the eighth postoperative day (range 3-76). Completion gastrectomy (p = 0.048) and longer hospital stay (p < 0.001) were associated with the occurrence of EJF. The surgical mortality of patients with EJF was higher than in non-EJF patients (26.7% vs. 4.5%; p < 0.001). Nine patients were treated conservatively and six required surgery. The mortality rate of EJF was 11.1% and 50% in patients who underwent conservative and surgical treatment, respectively. Patients with other complications and patients with EJF had worse survival compared to patients without any complication (p = 0.004 and p = 0.013, respectively). Completion gastrectomy is the main risk factor for EJF occurrence. Still, EJF is associated with high postoperative mortality, longer hospital stay and has a negative impact on long-term survival.eng
dc.description.indexMEDLINEeng
dc.identifier.citationUPDATES IN SURGERY, v.71, n.3, p.429-438, 2019
dc.identifier.doi10.1007/s13304-019-00659-8
dc.identifier.eissn2038-3312
dc.identifier.issn2038-131X
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/33485
dc.language.isoeng
dc.publisherSPRINGER-VERLAG ITALIA SRLeng
dc.relation.ispartofUpdates in Surgery
dc.rightsrestrictedAccesseng
dc.rights.holderCopyright SPRINGER-VERLAG ITALIA SRLeng
dc.subjectStomach neoplasmseng
dc.subjectGastrectomyeng
dc.subjectPostoperative complicationseng
dc.subjectDigestive system fistulaeng
dc.subject.otherlong-term survivaleng
dc.subject.othergastric-cancereng
dc.subject.otherpostoperative complicationseng
dc.subject.otherleakageeng
dc.subject.otherriskeng
dc.subject.otheresophagealeng
dc.subject.otherresectioneng
dc.subject.othersurgeryeng
dc.subject.otherimpacteng
dc.subject.otherclassificationeng
dc.subject.wosSurgeryeng
dc.titleEsophagojejunal anastomotic fistula: a major issue after radical total gastrectomyeng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.citation.scopus11
hcfmusp.contributor.author-fmusphcLEANDRO CARDOSO BARCHI
hcfmusp.contributor.author-fmusphcMARCUS FERNANDO KODAMA PERTILLE RAMOS
hcfmusp.contributor.author-fmusphcMARINA ALESSANDRA PEREIRA
hcfmusp.contributor.author-fmusphcANDRE RONCON DIAS
hcfmusp.contributor.author-fmusphcULYSSES RIBEIRO JUNIOR
hcfmusp.contributor.author-fmusphcBRUNO ZILBERSTEIN
hcfmusp.contributor.author-fmusphcIVAN CECCONELLO
hcfmusp.description.beginpage429
hcfmusp.description.endpage438
hcfmusp.description.issue3
hcfmusp.description.volume71
hcfmusp.origemWOS
hcfmusp.origem.pubmed31161587
hcfmusp.origem.scopus2-s2.0-85067054536
hcfmusp.origem.wosWOS:000479252600004
hcfmusp.publisher.cityMILANeng
hcfmusp.publisher.countryITALYeng
hcfmusp.relation.referenceAloia TA, 2014, J SURG ONCOL, V110, P107, DOI 10.1002/jso.23626eng
hcfmusp.relation.referenceAurello P, 2015, AM SURGEON, V81, P450eng
hcfmusp.relation.referenceBarchi LC, 2019, ABCD-ARQ BRAS CIR DI, V32, DOI 10.1590/0102-672020180001e1425eng
hcfmusp.relation.referenceBarchi LC, 2016, TRANSL GASTROENT HEP, V1, DOI 10.21037/tgh.2016.12.05eng
hcfmusp.relation.referenceBarchi LC, 2016, ABCD-ARQ BRAS CIR DI, V29, P117, DOI 10.1590/0102-6720201600020013eng
hcfmusp.relation.referenceBudisin N, 2001, J SURG ONCOL, V77, P35, DOI 10.1002/jso.1063eng
hcfmusp.relation.referenceBusweiler LAD, 2017, J SURG ONCOL, V115, P738, DOI 10.1002/jso.24562eng
hcfmusp.relation.referenceCarboni F, 2016, J GASTROINTEST ONCOL, V7, P515, DOI 10.21037/jgo.2016.06.02eng
hcfmusp.relation.referenceCHARLSON ME, 1987, J CHRON DIS, V40, P373, DOI 10.1016/0021-9681(87)90171-8eng
hcfmusp.relation.referenceDasari BVM, 2014, ANN SURG, V259, P852, DOI 10.1097/SLA.0000000000000564eng
hcfmusp.relation.referenceDeguchi Y, 2012, WORLD J SURG, V36, P1617, DOI 10.1007/s00268-012-1559-3eng
hcfmusp.relation.referenceDindo D, 2004, ANN SURG, V240, P205, DOI 10.1097/01.sla.0000133083.54934.aeeng
hcfmusp.relation.referenceGirard E, 2014, J VISC SURG, V151, P441, DOI 10.1016/j.jviscsurg.2014.10.004eng
hcfmusp.relation.referenceGong WB, 2017, INT J SURG, V47, P18, DOI 10.1016/j.ijsu.2017.09.019eng
hcfmusp.relation.referenceHyodo M, 2007, DIGEST SURG, V24, P169, DOI 10.1159/000102100eng
hcfmusp.relation.referenceIrlbeck T, 2017, ANAESTHESIST, V66, P5, DOI 10.1007/s00101-016-0246-4eng
hcfmusp.relation.referenceJapanese Gastric Canc Assoc, 2017, GASTRIC CANCER, V20, P1, DOI 10.1007/s10120-016-0622-4eng
hcfmusp.relation.referenceKim SH, 2015, J GASTRIC CANCER, V15, P167, DOI 10.5230/jgc.2015.15.3.167eng
hcfmusp.relation.referenceRamos MFKP, 2019, ABCD-ARQ BRAS CIR DI, V32, DOI 10.1590/0102-672020190001e1435eng
hcfmusp.relation.referenceRamos MFKP, 2018, INT J SURG, V53, P366, DOI 10.1016/j.ijsu.2018.03.082eng
hcfmusp.relation.referenceLang H, 2000, EUR J SURG ONCOL, V26, P168, DOI 10.1053/ejso.1999.0764eng
hcfmusp.relation.referenceLi QG, 2013, WORLD J GASTROENTERO, V19, P4060, DOI 10.3748/wjg.v19.i25.4060eng
hcfmusp.relation.referenceMasoomi H, 2011, ARCH SURG-CHICAGO, V146, P1048, DOI 10.1001/archsurg.2011.203eng
hcfmusp.relation.referenceMessager M, 2017, EJSO-EUR J SURG ONC, V43, P258, DOI 10.1016/j.ejso.2016.06.394eng
hcfmusp.relation.referenceMeyer L, 2005, LANGENBECK ARCH SURG, V390, P510, DOI 10.1007/s00423-005-0575-2eng
hcfmusp.relation.referenceMigita K, 2012, J GASTROINTEST SURG, V16, P1659, DOI 10.1007/s11605-012-1932-4eng
hcfmusp.relation.referenceNomura S, 2000, GASTRIC CANCER, V3, P97, DOI 10.1007/PL00011703eng
hcfmusp.relation.referenceOh SJ, 2009, J GASTROINTEST SURG, V13, P239, DOI 10.1007/s11605-008-0716-3eng
hcfmusp.relation.referenceOnodera H, 2004, DIGEST SURG, V21, P146, DOI 10.1159/000078381eng
hcfmusp.relation.referencePasquer A, 2016, ANN SURG, V264, P823, DOI 10.1097/SLA.0000000000001768eng
hcfmusp.relation.referencePournaras DJ, 2018, WORLD J SURG, V42, P2507, DOI 10.1007/s00268-018-4463-7eng
hcfmusp.relation.referenceRamos MFKP, 2015, ABCD-ARQ BRAS CIR DI, V28, P216, DOI 10.1590/S0102-67202015000300018eng
hcfmusp.relation.referenceSano T, 2002, BRIT J SURG, V89, P123eng
hcfmusp.relation.referenceSelby LV, 2017, JAMA SURG, V152, P953, DOI 10.1001/jamasurg.2017.1718eng
hcfmusp.relation.referenceSelby LV, 2015, J AM COLL SURGEONS, V220, P863, DOI 10.1016/j.jamcollsurg.2015.01.058eng
hcfmusp.relation.referenceSierzega M, 2010, BRIT J SURG, V97, P1035, DOI 10.1002/bjs.7038eng
hcfmusp.relation.referenceTakahashi Hitoshi, 2006, Masui, V55, P79eng
hcfmusp.relation.referenceTakeuchi M, 2016, BMC SURG, V16, DOI 10.1186/s12893-016-0168-8eng
hcfmusp.relation.referenceTu RH, 2017, EJSO-EUR J SURG ONC, V43, P485, DOI 10.1016/j.ejso.2016.11.022eng
hcfmusp.relation.referenceTurkyilmaz A, 2010, SURG LAPARO ENDO PER, V20, P10, DOI 10.1097/SLE.0b013e3181cdebf4eng
hcfmusp.relation.referenceWashington K, 2010, ANN SURG ONCOL, V17, P3077, DOI 10.1245/s10434-010-1362-zeng
hcfmusp.relation.referenceWeidenhagen R, 2008, SURG ENDOSC, V22, P1818, DOI 10.1007/s00464-007-9706-xeng
hcfmusp.relation.referenceYoo HM, 2011, J SURG ONCOL, V104, P734, DOI 10.1002/jso.22045eng
hcfmusp.relation.referenceZilberstein B, 2014, ABCD-ARQ BRAS CIR DI, V27, P133, DOI 10.1590/S0102-67202014000200010eng
hcfmusp.relation.referenceZilberstein B, 2013, ABCD-ARQ BRAS CIR DI, V26, P2, DOI 10.1590/S0102-67202013000100002eng
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