Long Term Follow-Up of Drug Eluting Versus Bare Metal Stents in the Treatment of Saphenous Vein Graft Lesions
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Citações na Scopus
7
Tipo de produção
article
Data de publicação
2013
Título da Revista
ISSN da Revista
Título do Volume
Editora
WILEY-BLACKWELL
Autores
POZETTI, Antonio H.
CAMPOS, Carlos A.
LOPES, Augusto C.
ELLIS, Stephen G.
Citação
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, v.82, n.7, p.E856-E863, 2013
Resumo
Introduction: The safety and effectiveness of drug-eluting stent (DES) compared with bare metal stents (BMS) for the treatment of saphenous vein graft (SVG) disease is controversial, especially because of the lack of long-term follow-up. The aim of this study was to address the late outcome of DES versus BMS for the treatment of SVG lesions. Methods: A matched, case-control study included 82 patients in each group. Patients groups were matched by gender, age, clinical presentation, and diabetes. The primary study end point was occurrence of major adverse cardiovascular events (MACE). Secondary end points included death, cardiac death, myocardial infarction (MI), and target vessel revascularization (TVR). Results: Clinical and angiographic characteristics were similar between the groups. At 6 months, TVR (hazard ratio [HR] 6.12, 95% confidence interval [CI] 1.39 to 26.93, P = 0.05), and MACE (HR 2.54, 95% CI 1.08 to 5.98, P = 0.04) were higher in the BMS group. At 4 years the risks of MI (P = 0.21), TVR (P = 0.99), and MACE (P = 0.21) were similar between both groups. However, the rates of death (HR 2.74, 95% CI 1.11 to 6.74, P = 0.04) and cardiac death (HR 4.26, 95% CI 1.59 to 11.35, P = 0.01) were significantly higher in the BMS group. Conclusions: These results suggest that the use of DES compared with BMS in the treatment of SVG lesions reduces TVR and MACE at 6 months of follow-up, a benefit that was lost over the next 3-4 years. (C) 2012 Wiley Periodicals, Inc.
Palavras-chave
drug eluting stents, bare metal stents, saphenous vein grafts, percutaneous coronary intervention, long term follow-up
Referências
- Applegate RJ, 2008, CATHETER CARDIO INTE, V72, P7, DOI 10.1002/ccd.21566
- Assali Abid, 2008, EuroIntervention, V4, P108, DOI 10.4244/EIJV4I1A18
- Baldwin DE, 2010, AM J CARDIOL, V106, P946, DOI 10.1016/j.amjcard.2010.05.025
- BOURASSA MG, 1985, CIRCULATION, V72, P71
- Brilakis ES, 2011, JACC-CARDIOVASC INTE, V4, P176, DOI 10.1016/j.jcin.2010.10.003
- Brilakis ES, 2009, J AM COLL CARDIOL, V53, P919, DOI 10.1016/j.jacc.2008.11.029
- Brilakis ES, 2010, EUROINTERVENTION, V5, P722, DOI 10.4244/EIJV5I6A119
- Brilakis ES, 2010, JACC-CARDIOVASC INTE, V3, P1068, DOI 10.1016/j.jcin.2010.07.009
- Brodie BR, 2009, JACC-CARDIOVASC INTE, V2, P1105, DOI 10.1016/j.jcin.2009.08.020
- Brunner-La Rocca HP, 2007, EUR HEART J, V28, P719, DOI 10.1093/eurheartj/ehl490
- Chakravarty T, 2012, CATHETER CARDIO INTE, V79, P903, DOI 10.1002/ccd.23187
- Coolong A, 2008, CIRCULATION, V117, P790, DOI 10.1161/CIRCULATIONAHA.106.651232
- deJaegere PP, 1996, J AM COLL CARDIOL, V28, P89, DOI 10.1016/0735-1097(96)00104-0
- Ellis SG, 1997, AM J CARDIOL, V79, P1460
- FITZGIBBON GM, 1991, J AM COLL CARDIOL, V17, P1075
- Gioia G, 2008, CATHETER CARDIO INTE, V72, P13, DOI 10.1002/ccd.21599
- Hakeem A, 2011, CATHETER CARDIO INTE, V77, P343, DOI 10.1002/ccd.22720
- Jeger RV, 2009, CARDIOLOGY, V112, P49, DOI 10.1159/000137699
- Lee MS, 2011, AM J CARDIOL, V105, P1076
- Mehilli J, 2011, LANCET, V378, P1071, DOI 10.1016/S0140-6736(11)61255-5
- Morice M, 2002, NEW ENGL J MED, V346, P1773, DOI 10.1056/NEJMoa012843
- Moses JW, 2003, NEW ENGL J MED, V349, P1315, DOI 10.1056/NEJMoa035071
- Nauta ST, 2012, CATHETER CARDIO INTE, V79, P912, DOI 10.1002/ccd.23145
- NWASOKWA ON, 1995, ANN INTERN MED, V123, P528
- Okabe T, 2008, AM J CARDIOL, V102, P530, DOI 10.1016/j.amjcard.2008.04.041
- Pucelikova T, 2008, AM J CARDIOL, V101, P63, DOI 10.1016/j.amjcard.2007.07.048
- Ramana RK, 2008, CATHETER CARDIO INTE, V71, P886, DOI 10.1002/ccd.21552
- Sanchez-Recalde A, 2010, EUROINTERVENTION, V6, P149, DOI 10.4244/
- Savage MP, 1997, NEW ENGL J MED, V337, P740, DOI 10.1056/NEJM199709113371103
- Singh M, 2005, AM J CARDIOL, V96, P907, DOI 10.1016/j.amjcard.2005.05.045
- Stone GW, 2004, NEW ENGL J MED, V350, P221, DOI 10.1056/NEJMoa032441
- Testa L, 2010, EUROINTERVENTION, V6, P527, DOI 10.4244/EIJ30V6I4A87
- van Twisk Piet-Hein, 2008, EuroIntervention, V4, P311, DOI 10.4244/EIJV4I3A57
- Vermeersch P, 2006, J AM COLL CARDIOL, V48, P2423, DOI 10.1016/j.jacc.2006.09.021
- Vermeersch P, 2007, J AM COLL CARDIOL, V50, P261, DOI 10.1016/j.jacc.2007.05.010
- Vignali L, 2008, AM J CARDIOL, V101, P947, DOI 10.1016/j.amjcard.2007.11.055
- Wiisanen ME, 2010, JACC-CARDIOVASC INTE, V3, P1262, DOI 10.1016/j.jcin.2010.08.019