Anti-reflux versus conventional self-expanding metal stents in the palliation of esophageal cancer: A systematic review and meta-analysis

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article
Data de publicação
2022
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GEORG THIEME VERLAG KG
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ENDOSCOPY INTERNATIONAL OPEN, v.10, n.10, p.E1406-E1416, 2022
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Background and study aims Self-expanding metal stents (SEMS) are an effective palliative endoscopic therapy to reduce dysphagia in esophageal cancer. Gastroesophageal reflux disease (GERD) is a relatively common complaint after non-valved conventional SEMS placement. Therefore, valved self-expanding metal stents (SEMS-V) were designed to reduce the rate of GERD symptoms. We aimed to perform a systematic review and meta-analysis comparing the two stents. Material and methods This was a systematic review and meta-analysis including only randomized clinical trials (RCT) comparing the outcomes between SEMS-V and non-valved self-expanding metal stents (SEMS-NV) following the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. The risk of bias was assessed using the Cochrane Risk of Bias 2 tool. Data were analyzed with Review Manager Software. Quality of evidence was evaluated using Grading of Recommendations Assessment, Development, and Evaluation guidelines. Results Ten randomized clinical trials including a total of 467 patients, 234 in the SEMS-V group and 233 in the SEMS-NV group, were included. There were no statistically significant differences regarding GERD qualitative analysis (RD -0.17; 95% CI -0.67, 0.33; P= 0.5) and quantitative analysis (SMD -0.22; 95% CI -0.53, 0.08; P=0.15) technical success (RD -0.03; 95% CI -0.07, 0.01; P= 0.16), dysphagia improvement (RD -0.07; 95% CI -0.19, 0.06; P=0.30), and adverse events (RD 0.07; 95% CI -0.07, 0.20; P= 0.32). Conclusions Both SEMS-V and SEMS-NV are safe and effective in the palliation of esophageal cancer with similar rates of GERD, dysphagia relief, technical success, adverse events, stent migration, stent obstruction, bleeding, and improvement of the quality of life.
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Referências
  1. Ahmed O, 2021, CLIN GASTROENTEROL H, V19, P1780, DOI 10.1016/j.cgh.2021.03.046
  2. Al-Kaabi A, 2022, ACTA ONCOL, V61, P545, DOI 10.1080/0284186X.2021.2024878
  3. BLAZEBY JM, 1995, GUT, V37, P505, DOI 10.1136/gut.37.4.505
  4. Blomberg J, 2010, SCAND J GASTROENTERO, V45, P208, DOI 10.3109/00365520903443860
  5. Coron E, 2016, ENDOSC INT OPEN, V4, pE730, DOI 10.1055/s-0042-106960
  6. Cumpston M, 2019, COCHRANE DB SYST REV, DOI 10.1002/14651858.ED000142
  7. Dua KS, 2019, GASTROINTEST ENDOSC, V90, P64, DOI 10.1016/j.gie.2019.01.013
  8. Elliott JA, 2022, DIS ESOPHAGUS, V35, DOI 10.1093/dote/doab094
  9. Global Cancer Observatory, CANC TOD INT AG RES
  10. Homs MYV, 2004, GASTROINTEST ENDOSC, V60, P695, DOI 10.1016/S0016-5107(04)02047-4
  11. Hourneaux G, 2001, Acta Gastroenterol Latinoam, V31, P13
  12. Hozo SP., 2005, BMC MED RES METHODOL, V5, P13, DOI [10.1186/1471-2288-5-13, DOI 10.1186/1471-2288-5-13]
  13. IntHout J, 2016, BMJ OPEN, V6, DOI 10.1136/bmjopen-2015-010247
  14. Kaduthodil MJ., 2011, CARDIOVASC INTER RAD, V34, P492
  15. Khalafallah A, 2010, MEDITERR J HEMATOL I, V2, DOI [10.1136/bmj.l4898, 10.4084/MJHID.2010.005]
  16. Kumar S, 2022, DIS ESOPHAGUS, V35, DOI 10.1093/dote/doab085
  17. Laasch HU, 2002, RADIOLOGY, V225, P359, DOI 10.1148/radiol.2252011763
  18. Law R, 2018, SURG ENDOSC, V32, P675, DOI 10.1007/s00464-017-5720-9
  19. Mudumbi S, 2014, ENDOSCOPY, V46, P1106, DOI 10.1055/s-0034-1377916
  20. Osugi H, 2002, SURG ENDOSC, V16, P1478, DOI 10.1007/s00464-001-9235-y
  21. Page MJ, 2021, BMJ-BRIT MED J, V372, DOI [10.1136/bmj.n71, 10.1016/j.ijsu.2021.105906]
  22. Pandit S, 2019, WORLD J GASTRO ENDOS, V11, P271, DOI 10.4253/wjge.v11.i4.271
  23. Power C, 2007, DIS ESOPHAGUS, V20, P466, DOI 10.1111/j.1442-2050.2007.00696.x
  24. Reijm AN, 2019, ENDOSCOPY, V51, P18, DOI 10.1055/a-0644-2495
  25. Sabharwal T, 2008, J GASTROEN HEPATOL, V23, P723, DOI 10.1111/j.1440-1746.2008.05396.x
  26. Saito E, 2022, CANCER MED-US, V11, P1347, DOI 10.1002/cam4.4528
  27. Saranovic D, 2005, DIS ESOPHAGUS, V18, P230, DOI 10.1111/j.1442-2050.2005.00484.x
  28. Schoppmeyer K, 2007, DIS ESOPHAGUS, V20, P89, DOI 10.1111/j.1442-2050.2007.00646.x
  29. SEER Cancer Statistics Factsheets, SEER CANC STAT FACTS
  30. Senturk M, 2021, GASTROENT RES PRACT, V2021, DOI 10.1155/2021/8034948
  31. Shim CS, 2005, ENDOSCOPY, V37, P335, DOI 10.1055/s-2005-861113
  32. Spaander MCW, 2021, ENDOSCOPY, V53, P751, DOI 10.1055/a-1475-0063
  33. Spaander MCW, 2016, ENDOSCOPY, V48, P939, DOI 10.1055/s-0042-114210
  34. Turner D, 2021, GASTROENTEROLOGY, V160, P1570, DOI 10.1053/j.gastro.2020.12.031
  35. van Rossum PSN, 2018, NAT REV GASTRO HEPAT, V15, P235, DOI 10.1038/nrgastro.2017.162
  36. Vermeulen Bram D, 2018, Curr Treat Options Gastroenterol, V16, P260, DOI 10.1007/s11938-018-0181-3
  37. Wenger U, 2006, SURG ENDOSC, V20, P1675, DOI 10.1007/s00464-006-0088-2
  38. Yakoub D, 2008, WORLD J SURG, V32, P1996, DOI 10.1007/s00268-008-9654-1
  39. Yang ZM, 2021, J LAPAROENDOSC ADV S, V31, P783, DOI 10.1089/lap.2020.0666
  40. Zhao CL, 2021, VIDEOSURGERY MINIINV, V16, P633, DOI 10.5114/wiitm.2021.104205