Acute management of unstable angina and non-ST segment elevation myocardial infarction

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSILVA, Fernando Morita Fernandes
dc.contributor.authorPESARO, Antonio Eduardo Pereira
dc.contributor.authorFRANKEN, Marcelo
dc.contributor.authorWAJNGARTEN, Mauricio
dc.date.accessioned2016-02-24T17:24:29Z
dc.date.available2016-02-24T17:24:29Z
dc.date.issued2015
dc.description.abstractNon-ST segment elevation coronary syndrome usually results from instability of an atherosclerotic plaque, with subsequent activation of platelets and several coagulation factors. Its treatment aims to reduce the ischemic pain, limiting myocardial damage and decreasing mortality. Several antiplatelet and anticoagulation agents have been proven useful, and new drugs have been added to the therapeutic armamentarium in the search for higher anti-ischemic efficacy and lower bleeding rates. Despite the advances, the mortality, infarction and readmission rates remain high.
dc.description.abstractA síndrome coronária sem supradesnivelamento do ST geralmente resulta da instabilização de uma placa aterosclerótica, com subsequente ativação plaquetária e de diversos fatores de coagulação. O tratamento visa aliviar a dor isquêmica, limitar o dano miocárdico e diminuir a mortalidade. Diversos agentes antiagregantes e anticoagulantes provaram sua utilidade, e novas drogas passaram a compor o arsenal terapêutico, buscando maior eficácia anti-isquêmica e menores índices de sangramento. Apesar dos avanços, as taxas de mortalidade, infarto e reinternação ainda permanecem elevadas.
dc.description.indexMEDLINE
dc.identifier.citationEINSTEIN-SAO PAULO, v.13, n.3, p.454-461, 2015
dc.identifier.doi10.1590/S1679-45082015RW3172
dc.identifier.eissn2317-6385
dc.identifier.issn1679-4508
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/13124
dc.language.isoeng
dc.publisherInstituto Israelita de Ensino e Pesquisa Albert Einstein
dc.relation.ispartofEinstein (São Paulo)
dc.rightsopenAccess
dc.rights.holderCopyright Instituto Israelita de Ensino e Pesquisa Albert Einstein
dc.subjectAngina, unstable
dc.subjectMyocardial infarction
dc.subjectChest pain
dc.subjectMyocardial ischemia/drug therapy
dc.subjectAngina instável
dc.subjectInfarto do miocárdio
dc.subjectDor no peito
dc.subjectIsquemia miocárdica/quimioterapia
dc.titleAcute management of unstable angina and non-ST segment elevation myocardial infarction
dc.title.alternativeTratamento atual da síndrome coronária aguda sem supradesnivelamento do segmento ST
dc.typearticle
dc.type.categoryreview
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.author.externalSILVA, Fernando Morita Fernandes:Hospital Israelita Albert Einstein, Brazil
hcfmusp.author.externalPESARO, Antonio Eduardo Pereira:Hospital Israelita Albert Einstein, Brazil
hcfmusp.author.externalFRANKEN, Marcelo:Hospital Israelita Albert Einstein, Brazil
hcfmusp.citation.scopus9
hcfmusp.contributor.author-fmusphcMAURICIO WAJNGARTEN
hcfmusp.description.beginpage454
hcfmusp.description.endpage461
hcfmusp.description.issue3
hcfmusp.description.volume13
hcfmusp.origemWOS
hcfmusp.origem.pubmed26466065
hcfmusp.origem.scieloSCIELO:S1679-45082015000300454
hcfmusp.origem.scopus2-s2.0-84961037761
hcfmusp.origem.wosWOS:000421356600021
hcfmusp.publisher.citySão Paulo
hcfmusp.publisher.countryBRAZIL
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hcfmusp.scopus.lastupdate2024-04-12
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relation.isAuthorOfPublication.latestForDiscovery190dca9d-4517-4a03-af80-7277a0804b67
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