Comparação entre medidas objetivas do tabagismo e tabagismo autodeclarado em pacientes com asma ou DPOC: será que nossos pacientes dizem a verdade?
Carregando...
Citações na Scopus
47
Tipo de produção
article
Data de publicação
2015
Título da Revista
ISSN da Revista
Título do Volume
Editora
SOC BRASILEIRA PNEUMOLOGIA TISIOLOGIA
Citação
JORNAL BRASILEIRO DE PNEUMOLOGIA, v.41, n.2, p.124-132, 2015
Resumo
Objective: Smoking prevalence is frequently estimated on the basis of self-reported smoking status. That can lead to an underestimation of smoking rates. The aim of this study was to evaluate the difference between self-reported smoking status and that determined through the use of objective measures of smoking at a pulmonary outpatient clinic. Methods: This was a cross-sectional study involving 144 individuals: 51 asthma patients, 53 COPD patients, 20 current smokers, and 20 never-smokers. Smoking status was determined on the basis of self-reports obtained in interviews, as well as through tests of exhaled carbon monoxide (eCO) and urinary cotinine. Results: All of the asthma patients and COPD patients declared they were not current smokers. In the COPD and asthma patients, the median urinary cotinine concentration was 167 ng/mL (range, 2-5,348 ng/mL) and 47 ng/mL (range, 5-2,735 ng/mL), respectively (p < 0.0001), whereas the median eCO level was 8 ppm (range, 0-31 ppm) and 5 ppm (range, 2-45 ppm), respectively (p < 0.05). In 40 (38%) of the patients with asthma or COPD (n = 104), there was disagreement between the self-reported smoking status and that determined on the basis of the urinary cotinine concentration, a concentration > 200 ng/mL being considered indicative of current smoking. In 48 (46%) of those 104 patients, the self-reported non-smoking status was refuted by an eCO level > 6 ppm, which is also considered indicative of current smoking. In 30 (29%) of the patients with asthma or COPD, the urinary cotinine concentration and the eCO level both belied the patient claims of not being current smokers. Conclusions: Our findings suggest that high proportions of smoking pulmonary patients with lung disease falsely declare themselves to be nonsmokers. The accurate classification of smoking status is pivotal to the treatment of lung diseases. Objective measures of smoking could be helpful in improving clinical management and counseling.
Palavras-chave
Asthma, Pulmonary disease, chronic obstructive, Cotinine, Carbon monoxide, Smoking
Referências
- Corbo GM, 2006, RESPIRATION, V73, P277, DOI 10.1159/000092081
- Cornette A, 1996, REV MAL RESPIR, V13, P405
- Cunnington AJ, 2002, POSTGRAD MED J, V78, P233, DOI 10.1136/pmj.78.918.233
- Deveci SE, 2004, RESP MED, V98, P551, DOI 10.1016/j.rmed.2003.11.018
- Dias SA, 2009, J BRAS PNEUMOL, V35, P261, DOI 10.1590/S1806-37132009000300011
- Gallus S, 2011, TOB CONTROL, V20, P34, DOI 10.1136/tc.2009.034132
- GLASGOW RE, 1993, ADDICT BEHAV, V18, P511, DOI 10.1016/0306-4603(93)90068-K
- Gorber SC, 2009, NICOTINE TOB RES, V11, P12, DOI 10.1093/ntr/ntn010
- Haufroid V, 1998, INT ARCH OCC ENV HEA, V71, P162, DOI 10.1007/s004200050266
- Kharitonov SA, 2001, AM J RESP CRIT CARE, V163, P1693
- Lores Obradors L, 1999, ARCH BRONCONEUMOL, V35, P219
- Malta DC, 2010, J BRAS PNEUMOL, V36, P75, DOI 10.1590/S1806-37132010000100013
- Middleton ET, 2000, CHEST, V117, P758, DOI 10.1378/chest.117.3.758
- Miller MR, 2005, EUR RESPIR J, V26, P319, DOI 10.1183/09031936.05.00034805
- MURRAY RP, 1993, AM J PUBLIC HEALTH, V83, P1251, DOI 10.2105/AJPH.83.9.1251
- Nakajima M, 2000, J CHROMATOGR B, V742, P211, DOI 10.1016/S0378-4347(00)00149-3
- Prado GF, 2011, CLINICS, V66, P65, DOI 10.1590/S1807-59322011000100012
- Price DB, 2006, RESPIRATION, V73, P285, DOI 10.1159/000090142
- Santos UP, 2001, J PNEUMOL, V27, P231
- Sato S, 2003, CHEST, V124, P1749, DOI 10.1378/chest.124.5.1749
- Scanlon PD, 2000, AM J RESP CRIT CARE, V161, P381
- Signorello LB, 2009, DIS MARKERS, V27, P187, DOI 10.3233/DMA-2009-0661
- Thomson NC, 2004, EUR RESPIR J, V24, P822, DOI 10.1183/09031936.04.00039004
- Tinkelman DG, 2006, RESPIRATION, V73, P296, DOI 10.1159/000090141
- Togores B, 2000, EUR RESPIR J, V15, P177, DOI 10.1034/j.1399-3003.2000.15a32.x
- Tricker AR, 2003, TOXICOLOGY, V183, P151, DOI 10.1016/S0300-483X(02)00513-9
- Vestbo J, 2013, AM J RESP CRIT CARE, V187, P347, DOI 10.1164/rccm.201204-0596PP
- Zielinska-Danch W, 2007, BIOMARKERS, V12, P484, DOI 10.1080/13547500701421341