Effects of continuous positive airway pressure on depression and anxiety symptoms in patients with obstructive sleep apnoea: results from the sleep apnoea cardiovascular Endpoint randomised trial and meta-analysis

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art_ZHENG_Effects_of_continuous_positive_airway_pressure_on_depression_2019.PDF (1.21 MB)
Citações na Scopus
38
Tipo de produção
article
Data de publicação
2019
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER
Autores
ZHENG, Danni
XU, Ying
YOU, Shoujiang
HACKETT, Maree L.
WOODMAN, Richard J.
LI, Qiang
WOODWARD, Mark
LOFFLER, Kelly A.
RODGERS, Anthony
Citação
ECLINICALMEDICINE, v.11, p.89-96, 2019
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Whether continuous positive airway pressure (CPAP) treatment can improve depression or anxiety symptoms in obstructive sleep apnoea (OSA) patients remains uncertain. Methods: Secondary analysis of the Sleep Apnea Cardiovascular Endpoints (SAVE) trial, combined with a systematic review of randomised evidence. The SAVE secondary analyses involved 2410 patients with co-existing moderate-severe OSA and established cardiovascular disease randomly allocated to CPAP treatment plus usual care or usual care alone and followed up for 3.7 (SD 1.6) years. We evaluated the effect of CPAP treatment on depression and anxiety caseness (scores >= 8 on the Hospital Anxiety and Depression Scale depression and anxiety subscales [HADS-D and HADS-A]) for OSA patients. Findings: CPAP treatment was associated with reduced odds of depression caseness (adjusted odds ratio [OR] 0.80, 95% confidence interval [CI] 0.65-0.98, P=0.031) compared to usual care in the SAVE trial and the treatment effect was greater in those with pre-existing depression symptoms. A systematic review of 20 randomised trials including 4255 participants confirmed a benefit of CPAP in reducing depression symptoms in OSA patients: the overall effect (standardised mean difference) was -0.18 (95% CI -0.24 to -0.12). No effect of CPAP treatment on anxiety caseness was found both in patients of the SAVE study (adjusted OR 0.98, 95% CI 0.78-1.24, P = 0.89) and the systematic review. Interpretation: CPAP reduces depression symptoms in patients with co-existing OSA and CVD independently of improvements in sleepiness. (C) 2019 Published by Elsevier Ltd.
Palavras-chave
Continuous positive airway pressure, Depression, Anxiety, Mood, Obstructive sleep apnoea, OSA, Cardiovascular diseases
URI
https://observatorio.fm.usp.br/handle/OPI/40574
Referências
  1. Aaronson JA, 2016, J CLIN SLEEP MED, V12, P533, DOI 10.5664/jcsm.5684
  2. Bardwell Wayne A, 2007, Behav Sleep Med, V5, P21, DOI 10.1207/s15402010bsm0501_2
  3. Barnes M, 2004, AM J RESP CRIT CARE, V170, P656, DOI 10.1164/rccm.200311-1571OC
  4. Beck AT, 1996, J PERS ASSESS, V67, P588, DOI 10.1207/s15327752jpa6703_13
  5. BJELLAND I, 2002, J PSYCHOSOM RES, V0052
  6. Canessa N, 2011, AM J RESP CRIT CARE, V183, P1419, DOI 10.1164/rccm.201005-0693OC
  7. Cipriani Andrea, 2018, Focus (Am Psychiatr Publ), V16, P420, DOI 10.1176/appi.focus.16407
  8. COOK RJ, 1995, BRIT MED J, V310, P452, DOI 10.1136/bmj.310.6977.452
  9. Drudi LM, 2018, JAMA CARDIOL, V3, P191, DOI 10.1001/jamacardio.2017.5064
  10. Engleman HM, 1997, THORAX, V52, P114, DOI 10.1136/thx.52.2.114
  11. Engleman HM, 1999, AM J RESP CRIT CARE, V159, P461, DOI 10.1164/ajrccm.159.2.9803121
  12. ENGLEMAN HM, 1994, LANCET, V343, P572, DOI 10.1016/S0140-6736(94)91522-9
  13. Engleman HM, 1998, THORAX, V53, P341, DOI 10.1136/thx.53.5.341
  14. Feng Y, 2015, NPJ PRIM CARE RESP M, V25, DOI 10.1038/npjpcrm.2015.5
  15. Gupta MA, 2016, SLEEP MED REV, V28, P55, DOI 10.1016/j.smrv.2015.07.002
  16. Gupta MA, 2015, J CLIN SLEEP MED, V11, P165, DOI 10.5664/jcsm.4466
  17. Haensel A, 2007, SLEEP BREATH, V11, P239, DOI 10.1007/s11325-007-0115-0
  18. Harris M, 2009, SLEEP MED REV, V13, P437, DOI 10.1016/j.smrv.2009.04.001
  19. Henke KG, 2001, AM J RESP CRIT CARE, V163, P911, DOI 10.1164/ajrccm.163.4.9910025
  20. Iftikhar IH, 2015, J CLIN SLEEP MED, V11, P475, DOI 10.5664/jcsm.4610
  21. Kahn M, 2013, INT J PSYCHOPHYSIOL, V89, P218, DOI 10.1016/j.ijpsycho.2013.05.010
  22. Kendzerska T, 2017, EUR RESPIR J, V49, DOI 10.1183/13993003.01361-2016
  23. Lee IS, 2012, SLEEP MED, V13, P161, DOI 10.1016/j.sleep.2011.09.005
  24. Lesperance F, 2002, CIRCULATION, V105, P1049, DOI 10.1161/hc0902.104707
  25. Lyall LM, 2018, LANCET PSYCHIAT, V5, P507, DOI 10.1016/S2215-0366(18)30139-1
  26. Marshall NS, 2005, THORAX, V60, P427, DOI 10.1136/thx.2004.032078
  27. Martinez-Ceron E, 2016, AM J RESP CRIT CARE, V194, P476, DOI 10.1164/rccm.201510-1942OC
  28. Martinez-Ceron E, 2016, SLEEP MED REV, V25, P121, DOI 10.1016/j.smrv.2015.03.002
  29. McEvoy RD, 2016, NEW ENGL J MED, V375, P919, DOI 10.1056/NEJMoa1606599
  30. Moher D, 2009, PLOS MED, V6, DOI [10.1371/journal.pmed.1000097, 10.1136/bmj.b2535, 10.1016/j.ijsu.2010.02.007]
  31. MONTGOMERY SA, 1979, BRIT J PSYCHIAT, V134, P382, DOI 10.1192/bjp.134.4.382
  32. Montserrat JM, 2001, AM J RESP CRIT CARE, V164, P608, DOI 10.1164/ajrccm.164.4.2006034
  33. Nyenhuis DL, 1999, J CLIN PSYCHOL, V55, P79, DOI 10.1002/(SICI)1097-4679(199901)55:1<79::AID-JCLP8>3.0.CO;2-7
  34. Ohayon MM, 2003, J CLIN PSYCHIAT, V64, P1195, DOI 10.4088/JCP.v64n1009
  35. Patil SP, 2019, J CLIN SLEEP MED, V15, P301, DOI 10.5664/jcsm.7638
  36. Povitz M, 2014, PLOS MED, V11, DOI 10.1371/journal.pmed.1001762
  37. Quan SF, 2011, SLEEP, V34, P303, DOI 10.1093/sleep/34.3.303
  38. Redline S, 1998, AM J RESP CRIT CARE, V157, P858, DOI 10.1164/ajrccm.157.3.9709042
  39. Rodway GW, 2010, SLEEP, V33, P260, DOI 10.1093/sleep/33.2.260
  40. Ryan CM, 2011, STROKE, V42, P1062, DOI 10.1161/STROKEAHA.110.597468
  41. Sandberg O, 2001, J AM GERIATR SOC, V49, P391, DOI 10.1046/j.1532-5415.2001.49081.x
  42. Saunamaeki T, 2007, ACTA NEUROL SCAND, V116, P277, DOI 10.1111/j.1600-0404.2007.00901.x
  43. Sharafkhaneh A, 2005, SLEEP, V28, P1405, DOI 10.1093/sleep/28.11.1405
  44. Stafford L, 2007, GEN HOSP PSYCHIAT, V29, P417, DOI 10.1016/j.genhosppsych.2007.06.005
  45. The Cochrane Collaboration, ASSESSING RISK BIAS
  46. Wheaton AG, 2012, SLEEP, V35, P461, DOI 10.5665/sleep.1724
  47. YESAVAGE JA, 1983, J PSYCHIATR RES, V17, P37, DOI 10.1016/0022-3956(82)90033-4
  48. Yu BH, 1999, J PSYCHIAT RES, V33, P427, DOI 10.1016/S0022-3956(99)00020-5
  49. Yu J, 2017, JAMA-J AM MED ASSOC, V318, P156, DOI 10.1001/jama.2017.7967
  50. Zhao YY, 2017, SLEEP, V40, DOI 10.1093/sleep/zsx040
  51. ZIGMOND AS, 1983, ACTA PSYCHIAT SCAND, V67, P361, DOI 10.1111/j.1600-0447.1983.tb09716.x

Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - FM/MCP
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/63
Artigos e Materiais de Revistas Científicas - ODS/03