Lidocaine 5% patch in the treatment of localized neuropathic pain due to nerve compression. Case reports

dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorLIGGIERI, André
dc.contributor.authorPALLADINI, Mariana
dc.date.accessioned2024-05-02T12:13:06Z
dc.date.available2024-05-02T12:13:06Z
dc.date.issued2023
dc.description.abstractABSTRACT BACKGROUND AND OBJECTIVES: Neuropathic pain is a chronic condition with a significant burden for patients, society, and healthcare systems. Due to neuropathic complexity, its management must be different than the one for nociceptive pain. First-line systemic treatments may be associated with dose-dependent adverse events and drug-drug interactions. On the other hand, topical treatments have less systemic adverse events, with the 5% lidocaine transdermal patch being recommended for firstor second line of treatment for neuropathic pain according to various international guidelines. The aim of this study is to present three cases of localized neuropathic pain due to nerve compression managed with 5% lidocaine transdermal patch. CASE REPORTS: The cases of three adult patients (>40 years old) with pain or tingling for a long period of time and their outcomes with treatment with 5% lidocaine transdermal patch for a prolonged duration were investigated. All three cases report a significant improvement in pain. CONCLUSION: The results of the reported cases revealed that a 5% lidocaine transdermal patch represents an effective, safe and tolerable and noninvasive option for the management of localized neuropathic pain due to peripheric nerve compression.eng
dc.description.abstractRESUMO JUSTIFICATIVA E OBJETIVOS: A dor neuropática é uma condição crônica com impactos significativos para o paciente, a sociedade e o sistema de saúde. Pela sua complexidade neuropática, a sua abordagem deve ser diferente da dor nociceptiva. Os tratamentos sistêmicos de primeira linha para a dor neuropática podem estar associados à incidência de eventos adversos dose-dependentes e interações farmacológicas. Por outro lado, os fármacos tópicos apresentam menor incidência de eventos adversos sistêmicos, sendo o emplastro de lidocaína a 5% recomendado como primeira ou segunda linha de tratamento para essa condição em diversos guidelines internacionais. O objetivo deste estudo foi apresentar três casos clínicos de dor neuropática localizada por compressão nervosa manejados com o emplastro de lidocaína a 5%. RELATO DOS CASOS: Três pacientes com idade superior a 40 anos e queixas de dor ou parestesia de longa duração foram manejados com emplastro de lidocaína a 5% em tratamento prolongado, com melhora da intensidade de dor expressiva. CONCLUSÃO: Os resultados dos casos reportados revelaram que o emplastro de lidocaína a 5% se apresentou como uma opção terapêutica eficaz, segura, bem tolerada e não invasiva no manejo da dor neuropática localizada por compressão nervosa periférica.por
dc.description.indexDimensions
dc.description.indexScielo
dc.identifier.citationBRJP, v.6, n.2, p.215-219, 2023
dc.identifier.doi10.5935/2595-0118.20230040-en
dc.identifier.issn2595-3192
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/76694
dc.language.isoengpor
dc.publisherSociedade Brasileira para o Estudo da Doreng
dc.relation.ispartofBrJP
dc.rightsopenAccesseng
dc.rights.holderCopyright Sociedade Brasileira para o Estudo da Doreng
dc.subjectLidocaineeng
dc.subjectNerve compressioneng
dc.subjectNeuropathic paineng
dc.subjectPaineng
dc.subjectCompressão nervosaeng
dc.subjectDoreng
dc.subjectDor neuropáticaeng
dc.subjectLidocaínaeng
dc.subject.wosHealth Care Sciences & Serviceseng
dc.titleLidocaine 5% patch in the treatment of localized neuropathic pain due to nerve compression. Case reportseng
dc.title.alternativeEmplastro de lidocaína a 5% no tratamento da dor neuropática localizada por compressão nervosa. Relato de casoseng
dc.typearticleeng
dc.type.categoryoriginal articleeng
dc.type.versionpublishedVersioneng
dspace.entity.typePublication
hcfmusp.author.externalPALLADINI, Mariana:Paulista Pain Center, Brazil; SBED Cannabinoid Committee, Brazil; NeuPSIG IASP, Brazil; SBED Neuropathic Pain Committee, Brazil; Neuropathic Pain Treatise, Brazil; Hospital Israelita Albert Einstein, Brazil
hcfmusp.contributor.author-fmusphcANDRE CICONE LIGGIERI
hcfmusp.description.beginpage215
hcfmusp.description.endpage219
hcfmusp.description.issue2
hcfmusp.description.volume6
hcfmusp.origemsciELO
hcfmusp.origem.dimensionspub.1163179511
hcfmusp.origem.scieloSCIELO:S2595-31922023000300215
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