Stroke lesion in cortical neural circuits and post-stroke incidence of major depressive episode: A 4-month prospective study

Imagem de Miniatura
Arquivos
art_TERRONI_Stroke_lesion_in_cortical_neural_circuits_and_poststroke_2011.PDF (360.92 KB)
Citações na Scopus
88
Tipo de produção
article
Data de publicação
2011
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
INFORMA HEALTHCARE
Autores
IOSIFESCU, Dan V.
Citação
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, v.12, n.7, p.539-548, 2011
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective. Little is known about the relevance of lesion in neural circuits reported to be associated with major depressive disorder. We investigated the association between lesion stroke size in the limbic-cortical-striatal-pallidal-thalamic (LCSPT) circuit and incidence of major depressive episode (MDE). Methods. We enrolled 68 patients with first-ever ischemic stroke and no history of major depressive disorder. Neurological and psychiatric examinations were performed at three time-points. We diagnosed major depressive episode, following DSM-IV criteria. Lesion location and volume were determined with magnetic resonance imaging, using a semi-automated method based on the Brodmann Cytoarchitectonic Atlas. Results. Twenty-one patients (31%) experienced major depressive episode. Larger lesions in the left cortical regions of the LCSPT circuit (3,760 vs. 660 mm(3); P = 0.004) were associated with higher incidence of MDE. Secondary analyses revealed that major depressive episode was associated with larger lesions in areas of the medial prefrontal cortex including the ventral (BA24) and dorsal anterior cingulate cortex (BA32) and subgenual cortex (BA25); and also the subiculum (BA28/36) and amygdala (BA34). Conclusions Our findings indicate that depression due to stroke is aetiologically related to the disruption of the left LCSPT circuit and support the relevance of the medial prefrontal cortex dysfunction in the pathophysiology of depression.
Palavras-chave
Cingulate gyrus, depression disorder, magnetic resonance imaging, prefrontal cortex, stroke
URI
https://observatorio.fm.usp.br/handle/OPI/22880
Referências
  1. American Psychiatric Association, 1994, DIAGN STAT MAN MENT
  2. Vataja R, 2004, J NEUROPSYCH CLIN N, V16, P156, DOI 10.1176/appi.neuropsych.16.2.156
  3. Fu CHY, 2004, ARCH GEN PSYCHIAT, V61, P877, DOI 10.1001/archpsyc.61.9.877
  4. Rorden C, 2000, BEHAV NEUROL, V12, P191
  5. HOCHBERG Y, 1988, BIOMETRIKA, V75, P800, DOI 10.1093/biomet/75.4.800
  6. Soares JC, 1997, J PSYCHIAT RES, V31, P393, DOI 10.1016/S0022-3956(97)00016-2
  7. Hackett ML, 2005, STROKE, V36, P2296, DOI 10.1161/01.STR.0000183622.75135.a4
  8. WILLIAMS JBW, 1988, ARCH GEN PSYCHIAT, V45, P742
  9. CUMMINGS JL, 1993, ARCH NEUROL-CHICAGO, V50, P873
  10. Bhogal SK, 2004, STROKE, V35, P794, DOI 10.1161/01.STR.0000117237.98749.26
  11. Friston KJ, 1996, CEREB CORTEX, V6, P156, DOI 10.1093/cercor/6.2.156
  12. BROTT T, 1989, STROKE, V20, P864
  13. Bessa JM, 2009, MOL PSYCHIATR, V14, P764, DOI 10.1038/mp.2008.119
  14. Bar M, 2009, TRENDS COGN SCI, V13, P456, DOI 10.1016/j.tics.2009.08.009
  15. Carson AJ, 2000, LANCET, V356, P122, DOI 10.1016/S0140-6736(00)02448-X
  16. Caeiro L, 2006, J PSYCHIATR NEUROSCI, V31, P377
  17. ROBINSON RG, 1984, BRAIN, V107, P81, DOI 10.1093/brain/107.1.81
  18. FAZEKAS F, 1987, AM J ROENTGENOL, V149, P351
  19. Pizzagalli D, 2001, AM J PSYCHIAT, V158, P405, DOI 10.1176/appi.ajp.158.3.405
  20. ANDERSEN G, 1995, ACTA PSYCHIAT SCAND, V92, P193, DOI 10.1111/j.1600-0447.1995.tb09567.x
  21. Goldapple K, 2004, ARCH GEN PSYCHIAT, V61, P34, DOI 10.1001/archpsyc.61.1.34
  22. ASTROM M, 1993, STROKE, V24, P976
  23. Lustman PJ, 2005, J DIABETES COMPLICAT, V19, P113, DOI 10.1016/j.jdiacomp.2004.01.002
  24. [Anonymous], 1989, STROKE, V20, P1407
  25. BAXTER LR, 1989, ARCH GEN PSYCHIAT, V46, P243
  26. Bar M, 2007, HIPPOCAMPUS, V17, P420, DOI 10.1002/hipo.20287
  27. Sheline YI, 2009, P NATL ACAD SCI USA, V106, P1942, DOI 10.1073/pnas.0812686106
  28. Mayberg HS, 2000, BIOL PSYCHIAT, V48, P830, DOI 10.1016/S0006-3223(00)01036-2
  29. Drevets WC, 2008, BRAIN STRUCT FUNCT, V213, P93, DOI 10.1007/s00429-008-0189-x
  30. Chen CH, 2008, NEUROPSYCHOPHARMACOL, V33, P1909, DOI 10.1038/sj.npp.1301593
  31. Hasler G, 2008, ARCH GEN PSYCHIAT, V65, P521, DOI 10.1001/archpsyc.65.5.521
  32. VanEssen DC, 1997, J NEUROSCI, V17, P7079
  33. Johansen-Berg H, 2008, CEREB CORTEX, V18, P1374, DOI 10.1093/cercor/bhm167
  34. Brody AL, 1999, PSYCHIAT RES-NEUROIM, V91, P127, DOI 10.1016/S0925-4927(99)00034-7
  35. Ongur D, 2003, J COMP NEUROL, V460, P425, DOI 10.1002/cne.10609
  36. DREVETS WC, 1992, J NEUROSCI, V12, P3628
  37. Ongur D, 2000, CEREB CORTEX, V10, P206, DOI 10.1093/cercor/10.3.206
  38. Mayberg HS, 1997, NEUROREPORT, V8, P1057, DOI 10.1097/00001756-199703030-00048
  39. Peluso MAM, 2009, PSYCHIAT RES-NEUROIM, V173, P158, DOI 10.1016/j.pscychresns.2009.03.006
  40. [Anonymous], 2009, MOL PSYCHIATR
  41. Beblo T, 1999, NEUROPSY NEUROPSY BE, V12, P236
  42. Brodmann K., 1909, BRODMANNS LOCALISATI, P298
  43. Conforto AB, 2008, ARQ NEURO-PSIQUIAT, V66, P308, DOI 10.1590/S0004-282X2008000300004
  44. Evans AC, 1993, P IEEE NUCL SCI S ME
  45. First MB, 1995, STRUCTURED CLIN INTE
  46. FOLSTEIN MF, 1975, J PSYCHIAT RES, V12, P189, DOI 10.1016/0022-3956(75)90026-6
  47. Herndon R, 1997, HDB NEUROLOGY RATING
  48. HERRMANN M, 1995, STROKE, V26, P850
  49. Iosifescu DV, 2007, J NERV MENT DIS, V195, P175, DOI 10.1097/01.nmd.0000253820.69362.87
  50. Iosifescu DV, 2006, BRIT J PSYCHIAT, V188, P180, DOI 10.1192/bjp.188.2.180
  51. Jamerson Brenda D, 2003, Psychopharmacol Bull, V37, P67
  52. MAYBERG HS, 1988, AM J PSYCHIAT, V145, P937
  53. RAMASUBBU R, 1994, CAN J PSYCHIAT, V39, P596
  54. ROBINSON RG, 1984, STROKE, V15, P510
  55. Singh A, 1998, CAN J PSYCHIAT, V43, P921
  56. SPALLETTA G, 2005, AM J GERIATR PSYCHIA, V13, P108, DOI 10.1176/appi.ajgp.13.2.108
  57. Talairach J., 1988, COPLANAR STEREOTAXIC
  58. Terroni LDN, 2009, REV BRAS PSIQUIATR, V31, P202, DOI 10.1590/S1516-44462009000300004
  59. Terroni Luisa de Marillac Niro, 2003, Rev. Assoc. Med. Bras., V49, P450, DOI 10.1590/S0104-42302003000400040
  60. Van Essen DC, 1998, P NATL ACAD SCI USA, V95, P788, DOI 10.1073/pnas.95.3.788
  61. Vataja R, 2001, ARCH GEN PSYCHIAT, V58, P925, DOI 10.1001/archpsyc.58.10.925
  62. Yu Lifa, 2004, Kaohsiung Journal of Medical Sciences, V20, P372

Coleções
Artigos e Materiais de Revistas Científicas - FM/MDR
Artigos e Materiais de Revistas Científicas - FM/MNE
Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InRad
Artigos e Materiais de Revistas Científicas - LIM/21
Carregar mais