Low bone mineral density among HIV-infected patients in Brazil

Página do item simplificado
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorCHABA, Daniela Cardeal da Silva
dc.contributor.authorSOARES, Lismeia R.
dc.contributor.authorPEREIRA, Rosa M. R.
dc.contributor.authorRUTHERFORD, George W.
dc.contributor.authorASSONE, Tatiane
dc.contributor.authorTAKAYAMA, Liliam
dc.contributor.authorFONSECA, Luiz A. M.
dc.contributor.authorDUARTE, Alberto J. S.
dc.contributor.authorCASSEB, Jorge
dc.date.accessioned2018-03-06T15:15:01Z
dc.date.available2018-03-06T15:15:01Z
dc.date.issued2017
dc.description.abstractDecrease in bone mineral density (BMD) has been a complication among people living with HIV/AIDS. To investigate the prevalence of osteopenia/osteoporosis among HIV-infected people living in Sao Paulo city, we studied 108 HIV-infected patients (79 men and 29 women). We extracted data from patients' medical records and BMD was measured by dual-energy X-ray absorptiometry (DXA). Median age of participants was 42 years (interquartile range [IQR] 36-48 years), and the median time since HIV diagnosis was 4.01 years (IQR 2-11 years). Patients had acquired HIV primarily by the sexual route (men who have sex with men 44%, heterosexual 49%). Median age, duration of HIV infection, duration of ART and CD4 nadir were similar for men and women. Plasma viral load was undetectable for 53 patients (49%). Median CD4 T cell count was 399 cells/mu L (IQR 247 - 568). Twenty five patients (23%) had LBMD, and there was no statistically significant difference between men and women (<-1). The associated risk factors for LBMD were older age (>= 50 years old) and smoking with a RR of 3.87 and 2.80, respectively. Thus, despite the lack of statistically significant relationship between the use of ART and LBMD or between duration of ART and LBMD, these factors should be addressed in larger studies.
dc.description.indexMEDLINE
dc.description.sponsorshipHIV Research Trust Scholarship (HIVRT) [HIVRT11-074]
dc.description.sponsorshipUniversity of California San Francisco from U.S. National Institutes of Health (NIH) Fogarty International Center (FIC) [D43TW005799]
dc.description.sponsorshipNational Institute of Mental Health (NIMH) International Traineeships in AIDS Prevention Studies (ITAPS) [R25MH064712]
dc.identifier.citationREVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO, v.59, article ID UNSP e89, 5p, 2017
dc.identifier.doi10.1590/S1678-9946201759089
dc.identifier.eissn1678-9946
dc.identifier.issn0036-4665
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/25497
dc.language.isoeng
dc.publisherINST MEDICINA TROPICAL SAO PAULO
dc.relation.ispartofRevista do Instituto de Medicina Tropical de Sao Paulo
dc.rightsopenAccess
dc.rights.holderCopyright INST MEDICINA TROPICAL SAO PAULO
dc.subjectHIV
dc.subjectBone mineral
dc.subjectOsteoporosis
dc.subjectRisk factors
dc.subject.otherbody-mass index
dc.subject.othersao-paulo city
dc.subject.otherantiretroviral therapy
dc.subject.otherrisk-factors
dc.subject.otherprevalence
dc.subject.otherosteoporosis
dc.subject.otherfracture
dc.subject.otherpopulation
dc.subject.otheroutpatient
dc.subject.otherosteopenia
dc.subject.wosTropical Medicine
dc.titleLow bone mineral density among HIV-infected patients in Brazil
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryEstados Unidos
hcfmusp.affiliation.countryisous
hcfmusp.author.externalCHABA, Daniela Cardeal da Silva:Univ Sao Paulo, Fac Med, Hosp Clin, Ambulatorio Imunodeficiencia Secundaria, Sao Paulo, SP, Brazil; Univ Sao Paulo, Fac Med, Lab Invest Med Neurol LIM 56, Sao Paulo, SP, Brazil; Univ Calif San Francisco, Global Hlth Sci, San Francisco, CA 94143 USA
hcfmusp.author.externalSOARES, Lismeia R.:Univ Fed Rio de Janeiro, Cursos Nutr, Rio De Janeiro, RJ, Brazil
hcfmusp.author.externalRUTHERFORD, George W.:Univ Calif San Francisco, Global Hlth Sci, San Francisco, CA 94143 USA
hcfmusp.citation.scopus8
hcfmusp.contributor.author-fmusphcROSA MARIA RODRIGUES PEREIRA
hcfmusp.contributor.author-fmusphcTATIANE ASSONE CASSEB
hcfmusp.contributor.author-fmusphcLILIAM TAKAYAMA GUERRA
hcfmusp.contributor.author-fmusphcLUIZ AUGUSTO MARCONDES FONSECA
hcfmusp.contributor.author-fmusphcALBERTO JOSE DA SILVA DUARTE
hcfmusp.contributor.author-fmusphcJORGE SIMAO DO ROSARIO CASSEB
hcfmusp.description.articlenumberUNSP e89
hcfmusp.description.volume59
hcfmusp.origemWOS
hcfmusp.origem.pubmed29267597
hcfmusp.origem.scieloSCIELO:S0036-46652017005000253
hcfmusp.origem.scopus2-s2.0-85041726464
hcfmusp.origem.wosWOS:000418613300015
hcfmusp.publisher.citySAO PAULO
hcfmusp.publisher.countryBRAZIL
hcfmusp.relation.referenceAlcalde R, 2012, VIROL J, V9, DOI 10.1186/1743-422X-9-156
hcfmusp.relation.referenceAraújo Denizar Vianna, 2005, Arq Bras Endocrinol Metab, V49, P897, DOI 10.1590/S0004-27302005000600007
hcfmusp.relation.referenceBaim S, 2008, J CLIN DENSITOM, V11, P75, DOI 10.1016/j.jocd.2007.12.007
hcfmusp.relation.referenceBonjoch A, 2010, AIDS, V24, P2827, DOI 10.1097/QAD.0b013e328340a28d
hcfmusp.relation.referenceBortolon PC, 2011, CAD SAUDE PUBLICA, V27, P733, DOI 10.1590/S0102-311X2011000400012
hcfmusp.relation.referenceBow CH, 2011, OSTEOPOROSIS INT, V22, P2799, DOI 10.1007/s00198-010-1490-0
hcfmusp.relation.referenceBrown TT, 2007, AIDS, V21, P1830, DOI 10.1097/QAD.0b013e3282703837
hcfmusp.relation.referenceBrown TT, 2006, AIDS, V20, P2165, DOI 10.1097/QAD.0b013e32801022eb
hcfmusp.relation.referenceCasseb J, 2012, REV INST MED TROP SP, V54, P257, DOI 10.1590/S0036-46652012000500004
hcfmusp.relation.referenceCazanave C, 2008, AIDS, V22, P395, DOI 10.1097/QAD.0b013e3282f423dd
hcfmusp.relation.referenceChitu-Tisu C. E., 2016, GERMS, V6, P50
hcfmusp.relation.referenceCotter AG, 2014, AIDS, V28, P2051, DOI 10.1097/QAD.0000000000000353
hcfmusp.relation.referenceEleftheriou KI, 2013, BONE, V52, P17, DOI 10.1016/j.bone.2012.09.003
hcfmusp.relation.referenceGrinsztejn B, 2013, PLOS ONE, V8, DOI 10.1371/journal.pone.0059768
hcfmusp.relation.referenceJones S, 2008, OSTEOPOROSIS INT, V19, P913, DOI 10.1007/s00198-007-0524-8
hcfmusp.relation.referenceLangkilde A, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0051698
hcfmusp.relation.referenceMalta M, 2015, BMC PUBLIC HEALTH, V15, DOI 10.1186/s12889-015-1530-y
hcfmusp.relation.referenceNunn AS, 2007, PLOS MED, V4, P1804, DOI 10.1371/journal.pmed.0040305
hcfmusp.relation.referenceNeto LFSP, 2011, J CLIN DENSITOM, V14, P434, DOI 10.1016/j.jocd.2011.06.004
hcfmusp.relation.referenceSales SH, 2015, SCI REP-UK, V5, DOI 10.1038/srep12990
hcfmusp.relation.referenceSchafer JJ, 2013, PHARMACOTHERAPY, V33, P665, DOI 10.1002/phar.1257
hcfmusp.relation.referenceSoares LR, 2015, REV INST MED TROP SP, V57, P105, DOI 10.1590/S0036-46652015000200002
hcfmusp.relation.referenceYin M, 2005, OSTEOPOROSIS INT, V16, P1345, DOI 10.1007/s00198-005-1845-0
hcfmusp.relation.referenceYong MK, 2011, JAIDS-J ACQ IMM DEF, V57, P205, DOI 10.1097/QAI.0b013e31821ecf4c
hcfmusp.relation.referenceYoung B, 2011, CLIN INFECT DIS, V52, P1061, DOI 10.1093/cid/ciq242
hcfmusp.relation.referenceZhang N, 2016, BIOSCI TRENDS, V10, P277, DOI 10.5582/bst.2016.01081
hcfmusp.scopus.lastupdate2024-05-10
relation.isAuthorOfPublicationa7d269ab-50f5-415f-a84f-b03f05f2093c
relation.isAuthorOfPublicationa2deec8d-19aa-48b1-bc11-ff5379f63e5e
relation.isAuthorOfPublication304910b3-77c3-4190-bd44-bb12480cd373
relation.isAuthorOfPublicatione3cb5925-7539-4ac9-aae8-04df78bc1048
relation.isAuthorOfPublication8e4f2c15-06a5-444b-826d-84576403144e
relation.isAuthorOfPublicationdb8fd0fe-568d-426b-b59b-955d4d21c0a9
relation.isAuthorOfPublication.latestForDiscoverya7d269ab-50f5-415f-a84f-b03f05f2093c
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
art_CHABA_Low_bone_mineral_density_among_HIVinfected_patients_in_2017.PDF
Tamanho:
169.1 KB
Formato:
Adobe Portable Document Format
Descrição:
publishedVersion (English)
Baixar
Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - FM/MPT
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - IMT
Artigos e Materiais de Revistas Científicas - LIM/17
Artigos e Materiais de Revistas Científicas - LIM/38
Carregar mais