Non-Detection of Human Herpesvirus 8 (HHV-8) DNA in HHV-8-Seropositive Blood Donors from Three Brazilian Regions

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorLEVI, Jose Eduardo
dc.contributor.authorNASCIMENTO, Maria Claudia
dc.contributor.authorSUMITA, Laura Masami
dc.contributor.authorSOUZA, Vanda Akico Ueda Fick de
dc.contributor.authorFREIRE, Wilton S.
dc.contributor.authorMAYAUD, Philippe
dc.contributor.authorPANNUTI, Claudio S.
dc.date.accessioned2017-11-27T16:28:13Z
dc.date.available2017-11-27T16:28:13Z
dc.date.issued2011
dc.description.abstractHuman herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is the etiologic agent of all forms of Kaposi's sarcoma, primary effusion lymphoma and the plasmablastic cell variant of multicentric Castleman disease. In endemic areas of sub-Saharan Africa, blood transfusions have been associated with a substantial risk of HHV-8 transmission. By contrast, several studies among healthy blood donors from North America have failed to detect HHV-8 DNA in samples of seropositive individuals. In this study, using a real-time PCR assay, we investigated the presence of HHV-8 DNA in whole-blood samples of 803 HHV-8 blood donors from three Brazilian states (Sao Paulo, Amazon, Bahia) who tested positive for HHV-8 antibodies, in a previous multicenter study. HHV-8 DNA was not detected in any sample. Our findings do not support the introduction of routine HHV-8 screening among healthy blood donors in Brazil. (WC = 140).
dc.description.indexMEDLINE
dc.description.sponsorshipConselho Nacional de Desenvolvimento Cientifico e Technologico (CNPq)
dc.description.sponsorshipagency of the Brazilian Ministry of Science and Technology [304879/2003-7, 305258/2006-0, 473867/2006-0]
dc.description.sponsorshipUK's Department for International Development (DFID)
dc.description.sponsorshipHIV in Developing Countries of the LSHTM
dc.identifier.citationPLOS ONE, v.6, n.8, article ID e23546, 4p, 2011
dc.identifier.doi10.1371/journal.pone.0023546
dc.identifier.issn1932-6203
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/23052
dc.language.isoeng
dc.publisherPUBLIC LIBRARY SCIENCE
dc.relation.ispartofPlos One
dc.rightsopenAccess
dc.rights.holderCopyright PUBLIC LIBRARY SCIENCE
dc.subject.otherhuman-herpesvirus type-8
dc.subject.otherlatent class analysis
dc.subject.otherkaposis-sarcoma
dc.subject.othermononuclear-cells
dc.subject.otherrisk-factors
dc.subject.otherviral load
dc.subject.othertransmission
dc.subject.othertransfusion
dc.subject.otherprevalence
dc.subject.otherinfection
dc.subject.wosMultidisciplinary Sciences
dc.titleNon-Detection of Human Herpesvirus 8 (HHV-8) DNA in HHV-8-Seropositive Blood Donors from Three Brazilian Regions
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryInglaterra
hcfmusp.affiliation.countryisogb
hcfmusp.author.externalMAYAUD, Philippe:London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London WC1, England
hcfmusp.citation.scopus15
hcfmusp.contributor.author-fmusphcJOSE EDUARDO LEVI
hcfmusp.contributor.author-fmusphcMARIA CLAUDIA DO NASCIMENTO
hcfmusp.contributor.author-fmusphcLAURA MASAMI SUMITA
hcfmusp.contributor.author-fmusphcVANDA AKICO UEDA
hcfmusp.contributor.author-fmusphcWILTON SANTOS FREIRE
hcfmusp.contributor.author-fmusphcCLAUDIO SERGIO PANNUTI
hcfmusp.description.articlenumbere23546
hcfmusp.description.issue8
hcfmusp.description.volume6
hcfmusp.origemWOS
hcfmusp.origem.pubmed21858163
hcfmusp.origem.scopus2-s2.0-79961178006
hcfmusp.origem.wosWOS:000293773300032
hcfmusp.publisher.citySAN FRANCISCO
hcfmusp.publisher.countryUSA
hcfmusp.relation.referenceKrishnan HH, 2004, J VIROL, V78, P3601, DOI 10.1128/JVI.78.7.3601-3620.2004
hcfmusp.relation.referenceHudnall SD, 2003, TRANSFUSION, V43, P85, DOI 10.1046/j.1537-2995.2003.00272.x
hcfmusp.relation.referenceUldrick TS, 2011, CANCER LETT, V305, P150, DOI 10.1016/j.canlet.2011.02.006
hcfmusp.relation.referenceBlackbourn DJ, 1997, LANCET, V349, P609, DOI 10.1016/S0140-6736(96)10004-0
hcfmusp.relation.referencePolstra AM, 2003, J CLIN MICROBIOL, V41, P5488, DOI 10.1128/JCM.41.12.5488-5491.2003
hcfmusp.relation.referenceDedicoat M, 2003, BRIT J CANCER, V88, P1, DOI 10.1038/sj.bjc.660745
hcfmusp.relation.referenceHudnall SD, 2008, TRANSFUSION, V48, P1180, DOI 10.1111/j.1537-2995.2008.01685.x
hcfmusp.relation.referenceQu LR, 2010, TRANSFUSION, V50, P1050, DOI 10.1111/j.1537-2995.2009.02559.x
hcfmusp.relation.referenceBelec L, 1998, TRANSFUSION, V38, P771, DOI 10.1046/j.1537-2995.1998.38898375517.x
hcfmusp.relation.referenceBigoni B, 1996, J INFECT DIS, V173, P542
hcfmusp.relation.referenceBrown EE, 2006, CANCER, V107, P2282, DOI 10.1002/cncr.22236
hcfmusp.relation.referenceBrown EE, 2005, INT J EPIDEMIOL, V34, P1110, DOI 10.1093/ije/dyi131
hcfmusp.relation.referenceCannon MJ, 2009, J INFECT DIS, V199, P1592, DOI 10.1086/598859
hcfmusp.relation.referenceEnbom M, 2002, J MED VIROL, V68, P264, DOI 10.1002/jmv.10183
hcfmusp.relation.referenceEngels EA, 2000, INT J CANCER, V88, P1003, DOI 10.1002/1097-0215(20001215)88:6<1003::AID-IJC26>3.0.CO;2-9
hcfmusp.relation.referenceEngels EA, 1999, J NATL CANCER I, V91, P1773, DOI 10.1093/jnci/91.20.1773
hcfmusp.relation.referenceFerreira S, 2003, TRANSFUSION, V43, P1764, DOI 10.1111/j.0041-1132.2003.00602.x
hcfmusp.relation.referenceHladik W, 2006, NEW ENGL J MED, V355, P1331, DOI 10.1056/NEJMoa055009
hcfmusp.relation.referenceLam LL, 2002, J CLIN MICROBIOL, V40, P325, DOI 10.1128/JCM.40.02.325-329.2002
hcfmusp.relation.referenceMartro E, 2004, J VIROL, V78, P11707, DOI 10.1128/JVI.78.21.11707-11714.2004
hcfmusp.relation.referenceMbulaiteye SM, 2003, J NATL CANCER I, V95, P1330, DOI 10.1093/jnci/djg039
hcfmusp.relation.referenceNascimento MC, 2007, J CLIN MICROBIOL, V45, P715, DOI 10.1128/JCM.01264-06
hcfmusp.relation.referenceNascimento MC, 2008, J MED VIROL, V80, P1202, DOI 10.1002/jmv.21188
hcfmusp.relation.referencePellett PE, 2003, TRANSFUSION, V43, P1260, DOI 10.1046/j.1537-2995.2003.00490.x
hcfmusp.relation.referenceQu L, 2011, VOX SANG, V100, P267, DOI 10.1111/j.1423-0410.2010.01404.x
hcfmusp.relation.referenceStramer SL, 2009, TRANSFUSION, V49, p1S, DOI 10.1111/j.1537-2995.2009.02279.x
hcfmusp.relation.referenceVitale F, 2000, EPIDEMIOL INFECT, V125, P671, DOI 10.1017/S0950268800004726
hcfmusp.scopus.lastupdate2024-05-17
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