Liver resection and transplantation offer similar 5-year survival for Child-Pugh-Turcotte A HCC-patients with a single nodule up to 5 cm: A multicenter, exploratory analysis

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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
dc.contributor.authorSILVA, M. F.
dc.contributor.authorSAPISOCHIN, G.
dc.contributor.authorSTRASSER, S. I.
dc.contributor.authorHEWA-GEEGANAGE, S.
dc.contributor.authorCHEN, J.
dc.contributor.authorWIGG, A. J.
dc.contributor.authorJONES, R.
dc.contributor.authorSARAIVA, R.
dc.contributor.authorKIKUCHI, L.
dc.contributor.authorCARRILHO, F.
dc.contributor.authorFONTES, P. R. O.
dc.contributor.authorCHARCO, R.
dc.date.accessioned2013-09-23T16:39:11Z
dc.date.available2013-09-23T16:39:11Z
dc.date.issued2013
dc.description.abstractBackground and aim: The current guideline of the American Association for the Study of Liver Diseases recommends liver resection for Child-Pugh-Turcotte A patients with a single hepatocellular carcinoma, total serum bilirubin <= 1 mg/dL and absence of significant portal hypertension. This subset of patients would have a long-term survival comparable to transplantation. The main aim of this study is to evaluate the survival rates in patients with a single nodule <= 5 cm following resection. Methods: Medical records of 105 Child-Pugh-Turcotte A patients who underwent liver resection between 1997 and 2009 were analyzed in 3 countries. Results: One, 3-, and 5-year survival rate was 97%, 83%, and 66%, respectively, and no variable that can be assessed prior to liver resection predicted survival probabilities. Conclusions: Liver resection offers 5-year survival similar to transplantation for Child-Pugh-Turcotte A patients with hepatocellular carcinoma and a single nodule up to 5 cm, independently of any patient baseline characteristics.
dc.description.indexMEDLINE
dc.identifier.citationEJSO, v.39, n.4, p.386-395, 2013
dc.identifier.doi10.1016/j.ejso.2012.12.011
dc.identifier.issn0748-7983
dc.identifier.urihttps://observatorio.fm.usp.br/handle/OPI/1944
dc.language.isoeng
dc.publisherELSEVIER SCI LTD
dc.relation.ispartofEjso
dc.rightsrestrictedAccess
dc.rights.holderCopyright ELSEVIER SCI LTD
dc.subjectHepatocellular carcinoma
dc.subjectLiver resection
dc.subjectLiver transplantation
dc.subject.otherearly hepatocellular-carcinoma
dc.subject.otherclass-a patients
dc.subject.otherhepatic resection
dc.subject.otherportal-hypertension
dc.subject.othermilan criteria
dc.subject.othersurgical resection
dc.subject.otherprognostic-factors
dc.subject.othercirrhotic-patients
dc.subject.otherrecurrence
dc.subject.otherpressure
dc.subject.wosOncology
dc.subject.wosSurgery
dc.titleLiver resection and transplantation offer similar 5-year survival for Child-Pugh-Turcotte A HCC-patients with a single nodule up to 5 cm: A multicenter, exploratory analysis
dc.typearticle
dc.type.categoryoriginal article
dc.type.versionpublishedVersion
dspace.entity.typePublication
hcfmusp.affiliation.countryAustrália
hcfmusp.affiliation.countryEspanha
hcfmusp.affiliation.countryisoes
hcfmusp.affiliation.countryisoau
hcfmusp.author.externalSILVA, M. F.:Flinders Univ S Australia, Dept Gastroenterol, Adelaide, SA 5001, Australia; Santa Casa Gen Hosp, Dept HBP Surg & Transplantat, BR-90450090 Porto Alegre, RS, Brazil; Univ Fed Ciencias Saude, Postgrad Course Hepatol, Porto Alegre, RS, Brazil
hcfmusp.author.externalSAPISOCHIN, G.:Univ Autonoma Barcelona, Hosp Univ Vall dHebron, Dept HBP Surg & Transplantat, Barcelona, Spain
hcfmusp.author.externalSTRASSER, S. I.:Royal Prince Alfred Hosp, Liver Transplant Unit, Sydney, NSW, Australia
hcfmusp.author.externalHEWA-GEEGANAGE, S.:Royal Prince Alfred Hosp, Liver Transplant Unit, Sydney, NSW, Australia
hcfmusp.author.externalCHEN, J.:Flinders Med Ctr, Liver Transplant Unit, Adelaide, SA, Australia
hcfmusp.author.externalWIGG, A. J.:Flinders Med Ctr, Liver Transplant Unit, Adelaide, SA, Australia
hcfmusp.author.externalJONES, R.:Austin Hosp, Liver Transplant Unit, Melbourne, Vic 3084, Australia
hcfmusp.author.externalSARAIVA, R.:Univ Sao Paulo, Sch Med, Dept Gastroenterol, Sao Paulo, Brazil
hcfmusp.author.externalFONTES, P. R. O.:Santa Casa Gen Hosp, Dept HBP Surg & Transplantat, BR-90450090 Porto Alegre, RS, Brazil; Univ Fed Ciencias Saude, Postgrad Course Hepatol, Porto Alegre, RS, Brazil
hcfmusp.author.externalCHARCO, R.:Univ Autonoma Barcelona, Hosp Univ Vall dHebron, Dept HBP Surg & Transplantat, Barcelona, Spain
hcfmusp.citation.scopus28
hcfmusp.contributor.author-fmusphcLUCIANA OBA ONISHI KIKUCHI
hcfmusp.contributor.author-fmusphcFLAIR JOSE CARRILHO
hcfmusp.description.beginpage386
hcfmusp.description.endpage395
hcfmusp.description.issue4
hcfmusp.description.volume39
hcfmusp.origemWOS
hcfmusp.origem.pubmed23375469
hcfmusp.origem.scopus2-s2.0-84875222199
hcfmusp.origem.wosWOS:000316511800012
hcfmusp.publisher.cityOXFORD
hcfmusp.publisher.countryENGLAND
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